Patents by Inventor Karin Langenberg

Karin Langenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vivo method for differentiating human pluripotent stem cells into atrial cardiomyocytes
    Patent number: 11773375
    Abstract: The present invention is in the field of pluripotent stem cells, more particularly cardiomyocytes derived from pluripotent stem cells. The present invention provides a novel method for differentiating human pluripotent stem cells into a population of cardiomyocytes having an atrial phenotype, and use of said atrial cardiomyocytes for screening of drugs, AF disease model, and others. The method of the invention is particularly useful to generate cardiomyocytes having a more developed or mature atrialphenotype and/or to generate higher yield of cardiomyocytes having an atrialphenotype.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: October 3, 2023
    Assignee: Ncardia B.V.
    Inventors: Stefan Robbert Braam, Ana Catarina Martins Grandela, Karin Langenberg
  • IN VIVO METHOD FOR DIFFERENTIATING HUMAN PLURIPOTENT STEM CELLS INTO ATRIAL CARDIOMYOCYTES
    Publication number: 20200216812
    Abstract: The present invention is in the field of pluripotent stem cells, more particularly cardiomyocytes derived from pluripotent stem cells. The present invention provides a novel method for differentiating human pluripotent stem cells into a population of cardiomyocytes having an atrial phenotype, and use of said atrial cardiomyocytes for screening of drugs, AF disease model, and others. The method of the invention is particularly useful to generate cardiomyocytes having a more developed or mature atrialphenotype and/or to generate higher yield of cardiomyocytes having an atrialphenotype.
    Type: Application
    Filed: March 27, 2017
    Publication date: July 9, 2020
    Inventors: Stefan Robbert Braam, Ana Catarina Martins Grandela, Karin Langenberg