Patents by Inventor Karin Lykke-Hartmann

Karin Lykke-Hartmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR USE IN REGULATING FOLLICLE MATURATION
    Publication number: 20230285375
    Abstract: Compounds and methods for treating infertility or reduced fertility in a female individual are provided, wherein a method includes taking primordial follicles from said individual, treating said follicles in vitro with an NRF2 modulator and re-inserting the treated follicles into said individual. An in vitro method of regulating primordial follicle maturation is provided, wherein the method includes contacting primordial follicles and an NRF2 modulator.
    Type: Application
    Filed: April 10, 2023
    Publication date: September 14, 2023
    Inventors: Karin Lykke-Hartmann, Emil Hagen Ernst, Anders Heuck
  • Compounds for use in regulating follicle maturation
    Patent number: 11666561
    Abstract: A compound and methods are provided for treating, preventing or ameliorating infertility or reduced fertility in an individual, wherein said compound is capable of regulating the activity of Nuclear Factor, Erythroid 2 Like 2 (NFE2L2).
    Type: Grant
    Filed: May 31, 2018
    Date of Patent: June 6, 2023
    Assignee: AARHUS UNIVERSITET
    Inventors: Karin Lykke-Hartmann, Emil Hagen Ernst, Anders Heuck
  • Compounds for promoting follicle maturation
    Publication number: 20230086706
    Abstract: Some analogues (eg. 3-carbamoyl-1-(tetrahydro-2H-pyran-4-yl)pyridin-1-ium, 3-carboxy-1-isopropylpyridin-1-ium, 1-benzyl-3-carbamoylpyridin-1-ium, 3-carbamoyl-1-methylpyridin-1-ium and cyclopamine) are disclosed to treat female infertility as the compounds increase the percentage of primary follicles relative to primordial follicles compared to control samples.
    Type: Application
    Filed: January 8, 2021
    Publication date: March 23, 2023
    Inventors: Karin Lykke-Hartmann, Gary Newton, Duncan Hannah, Robert Downham
  • COMPOUNDS FOR USE IN REGULATING FOLLICLE MATURATION
    Publication number: 20210145809
    Abstract: A compound and methods are provided for treating, preventing or ameliorating infertility or reduced fertility in an individual, wherein said compound is capable of regulating the activity of Nuclear Factor, Erythroid 2 Like 2 (NFE2L2).
    Type: Application
    Filed: May 31, 2018
    Publication date: May 20, 2021
    Inventors: Karin Lykke-Hartmann, Emil Hagen Ernst, Anders Heuck
  • COMPOUNDS FOR USE IN REGULATING FOLLICLE MATURATION
    Publication number: 20200316072
    Abstract: The present invention relates to a compounds and methods for regulating follicle maturation, and the use thereof in treating, preventing or ameliorating an ovulation disorder and methods for treating females having an ovulation disorder.
    Type: Application
    Filed: December 20, 2018
    Publication date: October 8, 2020
    Applicant: AARHUS UNIVERSITET
    Inventors: Karin Lykke-Hartmann, Emil Hagen Ernst, Anders Heuck