Patents by Inventor Karin O. Thomassian

Karin O. Thomassian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MASS SPECTROMETRIC QUANTITATION ASSAY FOR METABOLITES OF LEFLUNOMIDE
    Publication number: 20240118294
    Abstract: A method for determining an amount of teriflunomide in a sample by mass spectrometry includes adding an internal standard to the sample, subjecting the sample to solid phase extraction, purifying the sample by high turbulence liquid chromatography, ionizing the sample to produce one or more teriflunomide ions detectable by mass spectrometry, determining the amount of the one or more teriflunomide ions by mass spectrometry, and using the amount of the one or more ions determined to further determine the amount of teriflunomide in the sample.
    Type: Application
    Filed: December 18, 2023
    Publication date: April 11, 2024
    Inventor: Karin O. Thomassian
  • Mass spectrometric quantitation assay for metabolites of leflunomide
    Patent number: 11879900
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: January 23, 2024
    Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED
    Inventor: Karin O. Thomassian
  • MASS SPECTROMETRIC QUANTITATION ASSAY FOR METABOLITES OF LEFLUNOMIDE
    Publication number: 20220276267
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 1, 2022
    Inventor: Karin O. Thomassian
  • Mass spectrometric quantitation assay for metabolites of leflunomide
    Patent number: 11333673
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: May 17, 2022
    Assignee: Quest Diagnostics Investments Incorporated
    Inventor: Karin O. Thomassian
  • MASS SPECTROMETRIC QUANTITATION ASSAY FOR METABOLITES OF LEFLUNOMIDE
    Publication number: 20200217859
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 9, 2020
    Inventor: Karin O. Thomassian
  • Mass spectrometric quantitation assay for metabolites of leflunomide
    Patent number: 10598676
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: March 24, 2020
    Assignee: Quest Diagnostics Investments Incorporated
    Inventor: Karin O. Thomassian
  • MASS SPECTROMETRIC QUANTITATION ASSAY FOR METABOLITES OF LEFLUNOMIDE
    Publication number: 20180045743
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Application
    Filed: October 11, 2017
    Publication date: February 15, 2018
    Inventor: Karin O. Thomassian
  • Mass spectrometric quantitation for metabolites of leflunomide
    Patent number: 9817005
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: November 14, 2017
    Assignee: Quest Diagnostics Ivestments Incorporated
    Inventor: Karin O. Thomassian
  • MASS SPECTROMETRIC QUANTITATION FOR METABOLITES OF LEFLUNOMIDE
    Publication number: 20160061850
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Application
    Filed: November 2, 2015
    Publication date: March 3, 2016
    Inventor: Karin O. Thomassian
  • Mass spectrometric quantitation assay for metabolites of leflunomide
    Patent number: 9177766
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: November 3, 2015
    Assignee: Quest Diagnostics Investments Incorporated
    Inventor: Karin O. Thomassian
  • MASS SPECTROMETRIC QUANTITATION ASSAY FOR METABOLITES OF LEFLUNOMIDE
    Publication number: 20120171151
    Abstract: Methods are described for determining the amount of metabolites of leflunomide in a sample. More specifically, mass spectrometric methods are described for detecting and quantifying teriflunomide in a sample.
    Type: Application
    Filed: December 7, 2011
    Publication date: July 5, 2012
    Inventor: Karin O. Thomassian