Patents by Inventor Karin Pettenburger

Karin Pettenburger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for screening an expression cDNA clone bank for the detection of polynucleotides
    Patent number: 5837550
    Abstract: The invention relates to a method by which expression cDNA clone banks are screened by means of IgE antibodies derived from the sera of allergic individuals, or by means of monoclonal or polyclonal antibodies. This type of screening is used for the detection of polynucleotides whose open-reading frames code for allergenically active proteins. These proteins are characterized in that their biological activity as allergens is equal to that of plant allergens occurring in nature.
    Type: Grant
    Filed: June 7, 1994
    Date of Patent: November 17, 1998
    Assignee: Biomay Produktions-Und Handelsgesellschaft m.b.H.
    Inventors: Michael Breitenbach, Dietrich Kraft, Helmut Rumpold, Otto Scheiner, Heimo Breiteneder, Karin Pettenburger, Rudolf Valenta
  • Method for screening an expression cDNA clone bank for the detection of polynucleotides
    Patent number: 5786466
    Abstract: The invention relates to a method by which expression cDNA clone banks are screened by means of IgE antibodies derived from the sera of allergic individuals, or by means of monoclonal or polyconal antibodies. This type of screening is used for the detection of polynucleotides whose open-reading frames code for allergenically active proteins. These proteins are characterized in that their biological activity as allergens is equal to that of plant allergens occurring in nature.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 28, 1998
    Assignee: Biomay Produktions-Und Handelsgesellschaft m.b.h.
    Inventors: Michael Breitenbach, Dietrich Kraft, Helmut Rumpold, Otto Scheiner, Heimo Breiteneder, Karin Pettenburger, Rudolf Valenta
  • Method of production of birch pollen allergen P14
    Patent number: 5648242
    Abstract: The invention provides recombinant DNA molecules which code for polypeptides that exhibit the antigenicity of a P14 allergen of birch Betula verrucosa and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. A method is provided that permits purification of P14 allergens or cross reactive allergens by means of binding to poly(L-proline). In addition, methods are described for making the proteins and polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of diseases.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 15, 1997
    Assignee: Biomay Produktions - Und Handelsgesellschaft M.B.H.
    Inventors: Rudolf Valenta, Michael Duchene, Karin Pettenburger, Michael Breitenbach, Dietrich Kraft, Helmut Rumpold, Otto Scheiner
  • Birch pollen allergen P14 for diagnosis and therapy of allergic diseases
    Patent number: 5583046
    Abstract: The invention provides recombinant DNA molecules which code for proteins or polypeptides that exhibit the antigenicity of a P14 allergen of birch Betula verrucosa and other plants of the order Fagales, and for polypeptides comprising at least one epitope thereof, as well as nucleic acids which under stringent conditions hybridize with such DNA sequences or are derivable from such sequences by degeneracy of the genetic code. A method is provided that permits purification of P14 allergens or cross-reactive allergens by means of binding to poly(L-proline). In addition, methods are described for making the proteins and polypeptides coded by these DNA molecules and their use in the diagnosis or therapy of allergic diseases.
    Type: Grant
    Filed: June 6, 1992
    Date of Patent: December 10, 1996
    Assignee: Biomay Biotechnik Produktions Und Handelsgesellschaft m.b.H.
    Inventors: Rudolf Valenta, Michael Duchene, Karin Pettenburger, Michael Breitenbach, Dietrich Kraft, Helmut Rumpold, Otto Scheiner