Patents by Inventor Karin Przyklenk
Karin Przyklenk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12357841Abstract: A method of treating reperfusion injury in a tissue of a subject in need thereof. The method includes applying light, to the tissue, that inhibits electron transfer from cytochrome c to cytochrome c oxidase (CcO) to molecular oxygen to attenuate creation of reactive oxygen species. The light includes wavelengths in a first wavelength range of 730-770 nm and a second wavelength range of 930-970 nm.Type: GrantFiled: April 27, 2021Date of Patent: July 15, 2025Assignee: Wayne State UniversityInventors: Maik Huettemann, John Kamholz, Icksoo Lee, Karin Przyklenk, Lawrence Grossman, Thomas H. Sanderson
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Publication number: 20210252302Abstract: A method of treating reperfusion injury in a tissue of a subject in need thereof. The method includes applying light, to the tissue, that inhibits electron transfer from cytochrome c to cytochrome c oxidase (CcO) to molecular oxygen to attenuate creation of reactive oxygen species. The light includes wavelengths in a first wavelength range of 730-770 nm and a second wavelength range of 930-970 nm.Type: ApplicationFiled: April 27, 2021Publication date: August 19, 2021Inventors: Maik Huettemann, John Kamholz, Icksoo Lee, Karin Przyklenk, Lawrence Grossman, Thomas H. Sanderson
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Patent number: 11020604Abstract: A method of treating an ischemic event in tissue of a subject in need thereof, includes applying light to a tissue susceptible to ischemic reperfusion injury, the light having a wavelength selected from two wavelength ranges selected from 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm, thereby to reduce ischemic reperfusion injury in the tissue of the subject.Type: GrantFiled: June 27, 2018Date of Patent: June 1, 2021Assignee: Wayne State UniversityInventors: Maik Huttemann, Thomas Sanderson, John Kamholz, Kwaku Nantwi, Karin Przyklenk, Icksoo Lee, Lawrence Grossman
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Publication number: 20180304091Abstract: A method of treating an ischemic event in tissue of a subject in need thereof, includes applying light to a tissue susceptible to ischemic reperfusion injury, the light having a wavelength selected from two wavelength ranges selected from 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm, thereby to reduce ischemic reperfusion injury in the tissue of the subject.Type: ApplicationFiled: June 27, 2018Publication date: October 25, 2018Inventors: Maik Huttemann, Thomas Sanderson, John Kamholz, Kwaku Nantwi, Karin Przyklenk, Icksoo Lee, Lawrence Grossman
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Patent number: 10071261Abstract: A light therapy method, comprising identifying a pathological condition in a patient, selecting at least one light wavelength based on the identified pathological condition, and applying one or a combination of the selected light wavelengths to the patient using a light source.Type: GrantFiled: May 12, 2015Date of Patent: September 11, 2018Assignee: Wayne State UniversityInventors: Maik Huttemann, Thomas Sanderson, John Kamholz, Kwaku Nantwi, Karin Przyklenk, Icksoo Lee, Lawrence Grossman
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Patent number: 9610460Abstract: An exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event. Applying the light to the tissue inhibits cytochrome c oxidase activity. Another exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event and prior to either reoxygenation of the tissue or clinical intervention to reduce cell damage. An exemplary light therapy device includes at least one light source configured to generate light having a wavelength of at least one of approximately 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm.Type: GrantFiled: August 29, 2014Date of Patent: April 4, 2017Assignee: Wayne State UniversityInventors: Maik Huttemann, Icksoo Lee, John Kamholz, Lawrence Grossman, Karin Przyklenk, Thomas Sanderson
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Publication number: 20150246240Abstract: A light therapy method, comprising identifying a pathological condition in a patient, selecting at least one light wavelength based on the identified pathological condition, and applying one or a combination of the selected light wavelengths to the patient using a light source.Type: ApplicationFiled: May 12, 2015Publication date: September 3, 2015Inventors: Maik Huttemann, Thomas Sanderson, John Kamholz, Kwaku Nantwi, Karin Przyklenk, Icksoo Lee, Lawrence Grossman
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Patent number: 8945196Abstract: An exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event. Applying the light to the tissue inhibits cytochrome c oxidase activity. Another exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event and prior to either reoxygenation of the tissue or clinical intervention to reduce cell damage. An exemplary light therapy device includes at least one light source configured to generate light having a wavelength of at least one of approximately 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm.Type: GrantFiled: April 30, 2010Date of Patent: February 3, 2015Assignee: Wayne State UniversityInventors: Maik Huttemann, Icksoo Lee, John Kamholz, Lawrence Grossman, Karin Przyklenk, Thomas Sanderson
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Publication number: 20140371826Abstract: An exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event. Applying the light to the tissue inhibits cytochrome c oxidase activity. Another exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event and prior to either reoxygenation of the tissue or clinical intervention to reduce cell damage. An exemplary light therapy device includes at least one light source configured to generate light having a wavelength of at least one of approximately 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm.Type: ApplicationFiled: August 29, 2014Publication date: December 18, 2014Inventors: Maik Huttemann, Icksoo Lee, John Kamholz, Lawrence Grossman, Karin Przyklenk, Thomas Sanderson
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Publication number: 20110066213Abstract: An exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event. Applying the light to the tissue inhibits cytochrome c oxidase activity. Another exemplary method includes selecting at least one light source configured to generate light at a particular wavelength and applying the light to tissue following an ischemic event and prior to either reoxygenation of the tissue or clinical intervention to reduce cell damage. An exemplary light therapy device includes at least one light source configured to generate light having a wavelength of at least one of approximately 730-770 nm, 850-890 nm, 880-920 nm, and 930-970 nm.Type: ApplicationFiled: April 30, 2010Publication date: March 17, 2011Inventors: Maik Huttermann, Icksoo Lee, John Kamholz, Lawrence Grossman, Karin Przyklenk, Thomas Sanderson