Patents by Inventor Karin Tietje

Karin Tietje has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL INDOLES ARE CANNABINOID RECEPTOR LIGANDS
    Publication number: 20110065685
    Abstract: The present invention provides novel compounds of Formula (I) which are CB2 selective ligands useful for the treatment of pain.
    Type: Application
    Filed: June 14, 2010
    Publication date: March 17, 2011
    Applicant: Abbott Laboratories
    Inventors: Jennifer M. Frost, Karin Tietje, Michael J. Dart, Michael D. Meyer
  • Indoles are cannabinoid receptor ligands
    Patent number: 7750039
    Abstract: The present invention provides novel compounds of Formula (I) which are CB2 selective ligands useful for the treatment of pain.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: July 6, 2010
    Assignee: Abbott Laboratories
    Inventors: Jennifer M. Frost, Karin Tietje, Michael J. Dart, Michael D. Meyer
  • DIAZABICYCLIC CENTRAL NERVOUS SYSTEM ACTIVE AGENTS
    Publication number: 20080097094
    Abstract: Compounds of formula I pharmaceutical compositions of these compounds, and use of said compositions to control synaptic transmission in mammals.
    Type: Application
    Filed: December 15, 2007
    Publication date: April 24, 2008
    Applicant: Abbott Laboratories
    Inventors: Michael Schrimpf, Karin Tietje, Richard Toupence, Jianguo Ji, Anwer Basha, William Bunnelle, Jerome Daanen, Jennifer Frost, Kevin Sippy
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080064699
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L2, are defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 31, 2007
    Publication date: March 13, 2008
    Inventors: Alan Florjancic, Michael Dart, Keith Ryther, Arturo Perez-Medrano, William Carroll, Meena Patel, Karin Tietje, Tongmei Li, Teodozyj Kolasa, Megan Gallagher, Sridhar Peddi, Jennifer Frost, Derek Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080058335
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 30, 2007
    Publication date: March 6, 2008
    Inventors: Alan Florjancic, Michael Dart, Keith Ryther, Arturo Perez-Medrano, William Carroll, Meena Patel, Karin Tietje, Tongmei Li, Teodozyj Kolasa, Megan Gallagher, Sridhar Peddi, Jennifer Frost, Derek Nelson
  • Novel indoles are cannabinoid receptor ligands
    Publication number: 20070037801
    Abstract: The present invention provides novel compounds of Formula (I) which are CB2 selective ligands useful for the treatment of pain.
    Type: Application
    Filed: December 21, 2005
    Publication date: February 15, 2007
    Inventors: Jennifer Frost, Karin Tietje, Michael Dart, Michael Meyer
  • Azabicyclic compounds are central nervous system active agents
    Publication number: 20060287290
    Abstract: Compounds of formula (I) are novel CNS active agents that are useful for treating pain and for treating other disorders associated with the cholinergic system.
    Type: Application
    Filed: August 24, 2006
    Publication date: December 21, 2006
    Inventors: Michael Dart, Xenia Searle, Karin Tietje, Richard Toupence
  • Substituted diazabicycloalkane derivatives
    Publication number: 20050101602
    Abstract: Compounds of formula (I) Z-Ar1—Ar2??(I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by ?7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.
    Type: Application
    Filed: September 16, 2004
    Publication date: May 12, 2005
    Inventors: Anwer Basha, William Bunnelle, Michael Dart, Megan Gallagher, Jianguo Ji, Tao Li, Jennifer Pace, Keith Ryther, Karin Tietje, Kathleen Mortell, Diana Nersesian, Michael Schrimpf
  • Substituted diazabicycloakane derivatives
    Publication number: 20050065178
    Abstract: Compounds of formula (I) Z-Ar1—Ar2??(I) wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from an unsubstituted or substituted 5-membered heteroaryl ring; an unsubstituted or substituted 6-membered heteroaryl ring; 3,4-(methylenedioxy)phenyl; and phenyl substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by ?7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.
    Type: Application
    Filed: September 19, 2003
    Publication date: March 24, 2005
    Inventors: Anwer Basha, William Bunnelle, Michael Dart, Megan Gallagher, Jianguo Ji, Tao Li, Jennifer Pace, Keith Ryther, Karin Tietje
  • Azabicyclic compounds are central nervous system active agents
    Publication number: 20040044029
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: August 14, 2002
    Publication date: March 4, 2004
    Inventors: Michael J. Dart, Xenia B. Searle, Karin Tietje, Richard B. Toupence