Patents by Inventor Karina A. Orle

Karina A. Orle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NS5A nucleotide sequence variation as a marker for interferon response
    Publication number: 20050260567
    Abstract: Methods and reagents for determining a nucleotide variation at position 937 of the HCV-1a NS5A gene useful in predicting an individual's response to interferon treatment are presented.
    Type: Application
    Filed: April 27, 2005
    Publication date: November 24, 2005
    Inventors: Karina Orle, Andrew Ackrill, Morris Paterson
  • Methods and reagents for the detection of herpes simplex virus, treponema pallidum, and haemophilus ducreyi
    Patent number: 5508168
    Abstract: The present invention provides methods and reagents for the detection and identification of four causative agents of genital ulcerations, herpes simplex virus (HSV) types 1 and 2, Treponema pallidum, and Haemophilus ducreyi. The methods use sequence-specific primers which enable the simultaneous polymeric chain reaction amplification of genomic nucleic acid sequences from HSV types 1 and 2, T. pallidum, and H. ducreyi. Following amplification, sequence-specific oligonucleotide probes are used to detect and distinguish HSV type 1 and 2, T. pallidum, and H. ducreyi nucleic acid.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: April 16, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Karina A. Orle, Judith B. Weiss