Patents by Inventor Karina Cornelia Verhulst

Karina Cornelia Verhulst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant protein production in a human cell
    Publication number: 20090170164
    Abstract: Methods and compositions for the production of recombinant proteins in a human cell line. The methods and compositions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.
    Type: Application
    Filed: November 14, 2008
    Publication date: July 2, 2009
    Applicant: Crucell Holland B.V.
    Inventors: Abraham Bout, Guus Hatebaer, Karina Cornelia Verhulst, Alphonsus Gerarous Llytdehaas, Govert Johan Schonte
  • Recombinant protein production in a human cell
    Patent number: 7491532
    Abstract: Methods and compositions for the production of recombinant proteins in a eukaryotic cell line are disclosed. The methods and compositions are particularly useful for generating stable expression of recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.
    Type: Grant
    Filed: March 1, 2004
    Date of Patent: February 17, 2009
    Assignee: Crucell Holland, B.V.
    Inventors: Abraham Bout, Guus Hateboer, Karina Cornelia Verhulst, Alphonsus Gerardus Uytdehaag, Govert Johan Schouten
  • Recombinant protein production in a human cell
    Patent number: 7470523
    Abstract: Methods and compositions for the production of recombinant proteins in a human cell line. The methods and compositions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: December 30, 2008
    Assignee: Crucell Holland B.V.
    Inventors: Abraham Bout, Guus Hateboer, Karina Cornelia Verhulst, Alphonsus Gerardus Uytdehaag, Govert John Schouten
  • RECOMBINANT PROTEIN PRODUCTION IN A HUMAN CELL
    Publication number: 20080274497
    Abstract: Methods and compositions for the production of recombinant proteins in a eukaryotic cell line are disclosed. The methods and compositions are particularly useful for generating stable expression of recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.
    Type: Application
    Filed: March 1, 2004
    Publication date: November 6, 2008
    Inventors: Abraham Bout, Guus Hateboer, Karina Cornelia Verhulst, Alphonsus Gerardus Uytdehaag, Govert Johan Schouten
  • Recombinant protein production in a human cell
    Patent number: 7132280
    Abstract: Methods and compositions for the production of recombinant proteins in a human cell line. The methods and compositions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: November 7, 2006
    Assignee: Crucell Holland, B.V.
    Inventors: Abraham Bout, Guus Hateboer, Karina Cornelia Verhulst, Alphonsus Gerardus Uytdehaag, Govert Johan Schouten
  • Recombinant protein production in a human cell
    Patent number: 6855544
    Abstract: Methods and compositions for the production of recombinant proteins in a human cell line. The methods and positions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese Hamster Ovary cells.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: February 15, 2005
    Assignee: Crucell Holland B.V.
    Inventors: Guus Hateboer, Karina Cornelia Verhulst, Govert Johan Schouten, Alphonsus Gerardus Uytdehaag, Abraham Bout
  • Recombinant protein production in a human cell
    Publication number: 20030092160
    Abstract: Methods and compositions for the production of recombinant proteins in a human cell line. The methods and compositions are particularly useful for generating stable expression of human recombinant proteins of interest that are modified post-translationally, for example, by glycosylation. Such proteins may have advantageous properties in comparison with their counterparts produced in non-human systems such as Chinese hamster ovary cells.
    Type: Application
    Filed: September 3, 2002
    Publication date: May 15, 2003
    Inventors: Abraham Bout, Guus Hateboer, Karina Cornelia Verhulst, Alphonsus Gerardus Uytdehaag, Govert Johan Schouten