Patents by Inventor Karine Lelu-Santolaria

Karine Lelu-Santolaria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF IMMUNE DEPRESSION
    Publication number: 20230256057
    Abstract: The present invention is in the field of immunotherapy. The invention provides non-propagative viral vectors comprising a nucleic acid molecule encoding at least a polypeptide having an IL-7 activity, wherein said non-propagative viral vector is for use in the treatment of immune depression induced by sepsis, burn, trauma, major surgery, senescence and/or coronavirus.
    Type: Application
    Filed: July 13, 2021
    Publication date: August 17, 2023
    Applicant: Transgene
    Inventors: Geneviève INCHAUSPE, Perrine MARTIN, Stéphane LEUNG-THEUNG-LONG, Karine LELU-SANTOLARIA, Alexei EVLACHEV, Charles Antoine COUPET, Aurélie RAY, Clarisse DUBOIS
  • IMMUNOTHERAPEUTIC PRODUCT AND MDSC MODULATOR COMBINATION THERAPY
    Publication number: 20190328869
    Abstract: The present invention provides an immunotherapeutic composition for use in combination with one or more MDSC (Myeloid-derived suppressor cells) modulator(s) and a kit of parts comprising such components as well as methods using such components in combination. The invention also provides the use of Phosphodiesterase-5 (PDE5) inhibitors for reversing immunosuppression in chronic infectious diseases. The invention is of very special interest in treating or preventing diseases, especially chronic infectious diseases such as hepatitis B.
    Type: Application
    Filed: October 10, 2017
    Publication date: October 31, 2019
    Applicant: Transgene SA
    Inventors: Karine Lelu-Santolaria, Roland Kratzer, Perrine Martin