Patents by Inventor Karl A. J. Wretlind

Karl A. J. Wretlind has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5244925
    Abstract: The invention relates to emulsions intended for parenteral administration and contaning a hydrophobic phase emulsified in a an aqueous phase. In accordance with the invention, a substantial part of the hydrophobic phase contains one or more alkyl esters of pharmacologically acceptable fatty acids, and particularly their ethyl esters. The emulsions can be used for parenteral nutrient supply and as vehicles for pharmacologically active substances or agents and may also be used for both purposes in combination.
    Type: Grant
    Filed: October 8, 1991
    Date of Patent: September 14, 1993
    Assignee: Kabi Pharmacia Aktiebolag
    Inventors: Karl A. J. Wretlind, Bengt M. Ajaxon
  • Patent number: 4917880
    Abstract: The invention relates to an emulsion for use as an X-ray contrast agent and containing one or more iodinated lipids emulsified in an aqueous phase. The emulsion contains one or more amino acids, fatty acids or their salts, fat-soluble vitamins and/or urea for increasing its stability. Furthermore, the emulsion may contain one or more pharmacologically acceptable oils or fats.By the stability-increasing agent, it has been possible to prepare emulsions of iodinated lipids which can be sterilized in an autoclave and be stored for a long time without the emulsion breaking.
    Type: Grant
    Filed: June 10, 1988
    Date of Patent: April 17, 1990
    Assignee: Kabivitrum AB
    Inventors: Karl A. J. Wretlind, Bengt M. Ajaxon
  • Patent number: 4168308
    Abstract: According to the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.
    Type: Grant
    Filed: November 23, 1977
    Date of Patent: September 18, 1979
    Assignee: Apoteksvarucentralen Vitrum AB
    Inventors: Karl A. J. Wretlind, Stellan Ljungberg, Ivan Hakansson, Bengt M. Ajaxon
  • Patent number: 4073943
    Abstract: According to the method of the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.
    Type: Grant
    Filed: March 12, 1976
    Date of Patent: February 14, 1978
    Assignee: Apoteksvarucentralen Vitrum AB
    Inventors: Karl A. J. Wretlind, Stellan Ljungberg, Ivan Hakansson, Bengt M. Ajaxon
  • Patent number: RE32393
    Abstract: According to the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.
    Type: Grant
    Filed: August 14, 1984
    Date of Patent: April 7, 1987
    Assignee: KabiVitrum AB
    Inventors: Karl A. J. Wretlind, Stellan Ljungberg, Ivan Hakansson, Bengt M. Ajaxon