Patents by Inventor Karl A. Kelsey
Karl A. Kelsey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230193400Abstract: Ratio of neutrophils to lymphocytes (NLR) is here associated with immune suppression and decreased survival times in multiple solid tumors. Based on immune cell-specific DMRs and validated cell deconvolution algorithms, the NLR in blood from glioma patients was estimated and glioma patients had elevated mdNLR scores compared to controls. The patient mdNLR scores were increased in patients with grade IV tumors compared to grade II/III. High mdNLR scores were associated with shorter survival. Candidate single (myeloid-associated) gene loci that were highly correlated with the mdNLR were identified. Single myeloid differentiation loci provide a simpler and cheaper alternative to the mdNLR, which requires complex array data. Immunomethylomics are useful and more convenient than conventional cell analysis in profiling glioma risk and survival.Type: ApplicationFiled: September 30, 2022Publication date: June 22, 2023Inventors: Karl Kelsey, John Wiencke, Devin Koestler, Brock Christensen
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Publication number: 20220415165Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is described. An exemplary system has a first RFID interrogator and first and second antennas. The first and second antennas direct signals to and receive signals from respective first and second interrogation zones. A first interrogation signal is transmitted to the first antenna. A first acquire window for receiving a signal from a first RFID transponder is opened after the first interrogation signal. A second interrogation signal is transmitted to the second antenna after the first interrogation signal, and a second acquire window for receiving a signal from a second RFID transponder is opened after the second interrogation signal.Type: ApplicationFiled: August 26, 2022Publication date: December 29, 2022Applicant: AMTECH SYSTEMS, LLCInventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Patent number: 11450203Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is described. An exemplary system has a first RFID interrogator and first and second antennas. The first and second antennas direct signals to and receive signals from respective first and second interrogation zones. A first interrogation signal is transmitted to the first antenna. A first acquire window for receiving a signal from a first RFID transponder is opened after the first interrogation signal. A second interrogation signal is transmitted to the second antenna after the first interrogation signal, and a second acquire window for receiving a signal from a second RFID transponder is opened after the second interrogation signal.Type: GrantFiled: February 15, 2019Date of Patent: September 20, 2022Assignee: Amtech Systems, LLCInventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Patent number: 10619211Abstract: Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for diagnosing, prognosing and treating disease conditions, particularly cancer. The methods use fresh and archival samples.Type: GrantFiled: September 21, 2016Date of Patent: April 14, 2020Inventors: Karl Kelsey, Eugene Andres Houseman, John Wiencke, William P. Accomando, Jr., Carmen Marsit
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Publication number: 20190284636Abstract: Ratio of neutrophils to lymphocytes (NLR) is here associated with immune suppression and decreased survival times in multiple solid tumors. Based on immune cell-specific DMRs and validated cell deconvolution algorithms, the NLR in blood from glioma patients was estimated and glioma patients had elevated mdNLR scores compared to controls. The patient mdNLR scores were increased in patients with grade IV tumors compared to grade II/III. High mdNLR scores were associated with shorter survival. Candidate single (myeloid-associated) gene loci that were highly correlated with the mdNLR were identified. Single myeloid differentiation loci provide a simpler and cheaper alternative to the mdNLR, which requires complex array data. Immunomethylomics are useful and more convenient than conventional cell analysis in profiling glioma risk and survival.Type: ApplicationFiled: October 26, 2017Publication date: September 19, 2019Applicants: BROWN UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITY OF KANSAS, THE TRUSTEES OF DARTMOUTH COLLEGEInventors: Karl Kelsey, John Wiencke, Devin Koestler, Brock Christensen
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Publication number: 20190180611Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is described. An exemplary system has a first RFID interrogator and first and second antennas. The first and second antennas direct signals to and receive signals from respective first and second interrogation zones. A first interrogation signal is transmitted to the first antenna. A first acquire window for receiving a signal from a first RFID transponder is opened after the first interrogation signal. A second interrogation signal is transmitted to the second antenna after the first interrogation signal, and a second acquire window for receiving a signal from a second RFID transponder is opened after the second interrogation signal.Type: ApplicationFiled: February 15, 2019Publication date: June 13, 2019Inventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Patent number: 10210752Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is disclosed. An example is shown for an eight antenna system. A first four antennas arranged side-by-side are sequentially energized to interrogate RFID transponders. A second set of four antennas arranged side-by-side, the first of which is adjacent to the last of the first set of antennas. A four-antenna sequence is performed for the first four antennas and a second four antenna sequence is performed for the second set of antennas. The first and second four antenna sequences are offset by only a marginal amount, sufficient to ensure that a transponder signal received four antennas away from an active antenna is not acknowledged because the receive window for the non-active antenna is delayed.Type: GrantFiled: March 16, 2017Date of Patent: February 19, 2019Assignee: AMTECH SYSTEMS, LLCInventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Publication number: 20170186312Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is disclosed. An example is shown for an eight antenna system. A first four antennas arranged side-by-side are sequentially energized to interrogate RFID transponders. A second set of four antennas arranged side-by-side, the first of which is adjacent to the last of the first set of antennas. A four-antenna sequence is performed for the first four antennas and a second four antenna sequence is performed for the second set of antennas. The first and second four antenna sequences are offset by only a marginal amount, sufficient to ensure that a transponder signal received four antennas away from an active antenna is not acknowledged because the receive window for the non-active antenna is delayed.Type: ApplicationFiled: March 16, 2017Publication date: June 29, 2017Inventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Patent number: 9633238Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is disclosed. An example is shown for an eight antenna system. A first four antennas arranged side-by-side are sequentially energized to interrogate RFID transponders. A second set of four antennas arranged side-by-side, the first of which is adjacent to the last of the first set of antennas. A four-antenna sequence is performed for the first four antennas and a second four antenna sequence is performed for the second set of antennas. The first and second four antenna sequences are offset by only a marginal amount, sufficient to ensure that a transponder signal received four antennas away from an active antenna is not acknowledged because the receive window for the non-active antenna is delayed.Type: GrantFiled: December 3, 2014Date of Patent: April 25, 2017Assignee: AMTECH SYSTEMS, LLCInventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Publication number: 20170067121Abstract: Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for diagnosing, prognosing and treating disease conditions, particularly cancer. The methods use fresh and archival samples.Type: ApplicationFiled: September 21, 2016Publication date: March 9, 2017Inventors: Karl Kelsey, Eugene Andres Houseman, John Wiencke, William P. Accomando, JR., Carmen Marsit
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Publication number: 20150109108Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is disclosed. An example is shown for an eight antenna system. A first four antennas arranged side-by-side are sequentially energized to interrogate RFID transponders. A second set of four antennas arranged side-by-side, the first of which is adjacent to the last of the first set of antennas. A four-antenna sequence is performed for the first four antennas and a second four antenna sequence is performed for the second set of antennas. The first and second four antenna sequences are offset by only a marginal amount, sufficient to ensure that a transponder signal received four antennas away from an active antenna is not acknowledged because the receive window for the non-active antenna is delayed.Type: ApplicationFiled: December 3, 2014Publication date: April 23, 2015Inventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Patent number: 8928462Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is disclosed. An example is shown for an eight antenna system. A first four antennas arranged side-by-side are sequentially energized to interrogate RFID transponders. A second set of four antennas arranged side-by-side, the first of which is adjacent to the last of the first set of antennas. A four-antenna sequence is performed for the first four antennas and a second four antenna sequence is performed for the second set of antennas. The first and second four antenna sequences are offset by only a marginal amount, sufficient to ensure that a transponder signal received four antennas away from an active antenna is not acknowledged because the receive window for the non-active antenna is delayed.Type: GrantFiled: May 4, 2012Date of Patent: January 6, 2015Assignee: Amtech Systems, LLCInventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Publication number: 20140178348Abstract: Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for diagnosing, prognosing and treating disease conditions, particularly cancer. The methods use fresh and archival samples.Type: ApplicationFiled: November 25, 2013Publication date: June 26, 2014Applicants: The Regents of the University of California, Brown UniversityInventors: Karl Kelsey, Eugene Andres Houseman, John Wiencke, William P. Accomando, JR., Carmen Marsit
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Publication number: 20120280796Abstract: A method for interleaving time slots in a multi-antenna system for communication with RFID tags is disclosed. An example is shown for an eight antenna system. A first four antennas arranged side-by-side are sequentially energized to interrogate RFID transponders. A second set of four antennas arranged side-by-side, the first of which is adjacent to the last of the first set of antennas. A four-antenna sequence is performed for the first four antennas and a second four antenna sequence is performed for the second set of antennas. The first and second four antenna sequences are offset by only a marginal amount, sufficient to ensure that a transponder signal received four antennas away from an active antenna is not acknowledged because the receive window for the non-active antenna is delayed.Type: ApplicationFiled: May 4, 2012Publication date: November 8, 2012Applicant: AMTECH SYSTEMS, LLCInventors: Kelly Gravelle, Michael Melville, Karl Kelsey
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Patent number: 5726993Abstract: A loopback enabled by an instruction and address code pair transmitted with the regular data stream affords a simplified fault location scheme for a T1 repeater span. By selecting unique addresses for each repeater using a predetermined frame sequence and by testing for logic error density, erroneous enablement is avoided.Type: GrantFiled: August 19, 1996Date of Patent: March 10, 1998Assignee: Siemens Telecom NetworksInventors: Karl A. Kelsey, Romuald Bailey
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Patent number: 5600656Abstract: A loopback enabled by an instruction and address code pair transmitted with the regular data stream affords a simplified fault location scheme for a T1 repeater span. By selecting unique addresses for each repeater using a predetermined frame sequence and by testing for logic error density, erroneous enablement is avoided.Type: GrantFiled: October 25, 1995Date of Patent: February 4, 1997Assignee: Siemens Stromberg-CarlsonInventors: Karl A. Kelsey, Romuald Bailey