Patents by Inventor Karl-August Reiffen

Karl-August Reiffen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of determination of receptor binding saturation effected by monoclonal antibodies
    Patent number: 8445219
    Abstract: The invention relates to the determination of the degree of membrane receptor binding by specific monoclonal antibodies. This method is notably beneficial for monoclonal antibodies that are used in targeted therapies in order to define a target effective dose (TED). Especially the invention relates to the determination of the saturation degree of receptor binding effected by an anti-EGFR antibody of interest.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: May 21, 2013
    Assignee: Merck Patent GmbH
    Inventors: Karl-August Reiffen, Oliver Rosen
  • Method of Determination of Receptor Binding Saturation Effected by Monoclonal Antibodies
    Publication number: 20110136150
    Abstract: The invention relates to the determination of the degree of membrane receptor binding by specific monoclonal antibodies. This method is notably beneficial for monoclonal antibodies that are used in targeted therapies in order to define a target effective dose (TED). Especially the invention relates to the determination of the saturation degree of receptor binding effected by an anti-EGFR antibody of interest.
    Type: Application
    Filed: June 26, 2009
    Publication date: June 9, 2011
    Applicant: Merck Patent GmbH
    Inventors: Karl-August Reiffen, Oliver Rosen