Abstract: An autotransfuser includes, in a single receptacle, a pair of chambers separated by a common wall. Each receptacle can alternately perform a blood infusion or blood collection function. Each chamber includes at least three inlets/outlets, a blood inlet, a blood outlet and an air inlet. In some embodiments of the invention the air inlet serves alternately to couple either an air or a pressure source on the one hand or a vacuum source on the other hand to the corresponding chamber. In other embodiments of the invention, the air inlet comprises a vacuum inlet and a separate air or pressure inlet. A disk like device or valve manifold is arranged for rotatable movement adjacent the inlets/outlets. The disk like device includes four channels, one for each of air or pressure, vacuum, blood inlet and blood infusion. Each channel includes a port for coupling to external tubing and at least one channel end.