Patents by Inventor Karl-Dieter Voelger

Karl-Dieter Voelger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pteridine compounds
    Patent number: 4910203
    Abstract: Pteridine compounds, useful as diuretics, of the formula ##STR1## wherein R.sub.1 and R.sub.2 taken alone are, independently of each other, hydrogen, alkyl having from 1 to 6 carbon atoms, or benzyl, or wherein R.sub.1 and R.sub.2, taken together with the nitrogen atom to which they are bound, form a five- or six-membered heterocyclic ring system or such a ring containing one or two further hetero atoms, or wherein R.sub.1 and R.sub.
    Type: Grant
    Filed: April 20, 1988
    Date of Patent: March 20, 1990
    Inventors: Christian Rietzel, Heinrich Knauf, Ernst Mutschler, Karl-Dieter Voelger
  • 2,4,7-triamino-6-phenylpteridine
    Patent number: 4621085
    Abstract: The present invention relates to pharmaceutical preparations with cardiac, particularly anti-arrhythmic activity. These preparations comprise, as an active principle, at least one compound of formula I: ##STR1## where R represents a lipophilic radical. The pharmaceutical compositions may comprise this compound in the presence of other pharmaceutical excipients and adjuvants.
    Type: Grant
    Filed: April 3, 1985
    Date of Patent: November 4, 1986
    Assignee: Rohm GmbH Chemische Fabrik
    Inventors: Ulrich Borchard, Ernst Mutschler, Werner Moehrke, Karl-Dieter Voelger, Erwin Wolf
  • Treatment of Parkinson's disease
    Patent number: 4331687
    Abstract: What is disclosed is a method for the treatment of Parkinsonism or of psychic disturbances in a patient suffering therefrom, which method comprises orally or parenterally administering to said patient an effective amount of an active agent selected from the group consisting of (+)-trans-2-phenylcyclopropyl amine and physiologically acceptable acid addition salts thereof, said agent being essentially free of the corresponding (-)-enantiomer and its salts.
    Type: Grant
    Filed: March 3, 1981
    Date of Patent: May 25, 1982
    Assignee: Rohm Pharma GmbH
    Inventors: Karl-Dieter Voelger, Ilse Treudler
  • Substituted pteridine compounds and pharmaceutical compositions containing the same
    Patent number: 4252809
    Abstract: Pharmaceutical compositions having a diuretic effect and containing as the active ingredient a compound of the formula ##STR1## wherein R is hydrogen, a pharmaceutically acceptable cation, methyl, or a hydrophilic group R', are disclosed, as are novel compounds wherein R is R'.This application is a continuation-in-part of application Ser. No. 860,824 filed Dec. 15, 1977, now abandoned.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: February 24, 1981
    Assignee: Rohm Pharma GmbH
    Inventors: Heinrich Knauf, Ernst Mutschler, Karl-Dieter Voelger
  • Cardio-protective pharmaceutical composition
    Patent number: 4157394
    Abstract: A cardio-protective pharmaceutical composition is disclosed, which composition comprises an inert carrier and a pharmaceutically-effective amount of a combination of 2,4,7-triamino-6-phenyl-pteridine (triamterene) and a calcium antagonist, such as .alpha.-isopropyl-.alpha.-[(N-methyl-N-homoveratryl)-.gamma.-aminopropyl]- 3,4-dimethoxyphenyl-acetonitrile-hydrochloride (verapamil).
    Type: Grant
    Filed: December 19, 1977
    Date of Patent: June 5, 1979
    Assignee: Rohm Pharma GmbH
    Inventors: Albrecht Fleckenstein, Johanna Janke, Klaus Lossnitzer, Karl-Dieter Voelger
  • Diuretic pharmaceutical compositions and method of use containing the sulfuric acid half-ester of 2,4,7-triamino-6p-hydroxyphenyl pteridine
    Patent number: 4118492
    Abstract: A pharmaceutical composition for inducing diuresis, which composition comprises a diuretically-effective amount of the sulfuric acid half ester of 2,4,7-triamino-6-p-hydroxyphenyl pteridine or of a physiologically tolerable salt thereof in combination with a pharmaceutical carrier.
    Type: Grant
    Filed: March 31, 1977
    Date of Patent: October 3, 1978
    Assignee: Rohm GmbH
    Inventors: Karl-Dieter Voelger, Christian Rietzel, Klaus Lehmann