Patents by Inventor Karl Erik Hellström

Karl Erik Hellström has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of tumor cell growth by administration of B7-transfected cells
    Patent number: 6183734
    Abstract: The present invention is directed to a method of inhibiting tumor cell growth. Tumor cells from a pateint are recombinantly engineered to express the B7 surface protein and these cells are then readminsistered to the pateint. The presence of the B7 molecule on the tumor cell surface stimulates a broad immunologic response against both the B7-transfected and non-transfected tumor cells and results in the immunologic killing of localized and metastatic tumor cells. B7 transfection of the tumor cells, or cell membranes, serves as a stimulant to engender a potent immunologic response against the surface antigens present on the tumor cells.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: February 6, 2001
    Assignee: Bristol-Myers Squibb Company
    Inventors: Lieping Chen, Ingegerd Hellström, Karl Erik Hellström, Jeffrey A. Ledbetter, Peter S. Linsley