Patents by Inventor Karl F. Schmidt

Karl F. Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11147524
    Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: October 19, 2021
    Assignee: Biogen MA Inc.
    Inventors: Ajay Verma, Marisa J. Bober, Victoria Cabot, Courtney D. Hilliard, Ara N. Knaian, Seth O. Newburg, John William Hoppin, Karl F. Schmidt
  • Publication number: 20190200943
    Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 4, 2019
    Applicant: Biogen MA Inc.
    Inventors: Ajay Verma, Marisa J. Bober, Victoria Cabot, Courtney D. Hilliard, Ara N. Knaian, Seth O. Newburg, John William Hoppin, Karl F. Schmidt
  • Patent number: 10206639
    Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: February 19, 2019
    Assignee: Biogen MA Inc.
    Inventors: Ajay Verma, Marisa J. Bober, Victoria Cabot, Courtney D. Hilliard, Ara N. Knaian, Seth O. Newburg, John William Hoppin, Karl F. Schmidt
  • Publication number: 20170086763
    Abstract: Various embodiments of medical detector systems as well as their methods of operation are disclosed. In one embodiment, one or more detectors are coupled to wearable structures for detecting at least a first tracer within a body portion. In another embodiment, one or more detectors are coupled to a wearable structure, where the detector corresponds to a CMOS chip that directly detects a first radioactive tracer.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 30, 2017
    Applicant: Biogen MA Inc.
    Inventors: Ajay Verma, Marisa J. Bober, Victoria Cabot, Courtney D. Hilliard, Ara N. Knaian, Seth O. Newburg, John William Hoppin, Karl F. Schmidt
  • Publication number: 20140249413
    Abstract: Macrophages sequester and aggregate ultrasmall superparamagnetic iron oxide nanoparticles (USPIO) in their lysosomes. The amount of USPIO loading of macrophages depends upon the route and dose of administration, and the pharmacokinetics of accumulation and removal. Both fixed macrophages and activated macrophages associated with inflammatory diseases and cancer phagocytize USPIOs, and the loaded macrophages can serve to identify the extent of a macrophage-dependent disease as well as to direct treatment options. Furthermore, the absorption of energy from incident electromagnetic waves by the aggregated nanoparticles can be used for conformal thermotherapy. The USPIOs can further be used to carry drugs to the same activated macrophages. The co-administered drugs can be bound to the USPIO by condition-dependent releasing links that are responsive to local pH or heating.
    Type: Application
    Filed: March 10, 2014
    Publication date: September 4, 2014
    Inventors: Gerald L. Wolf, Karl F. Schmidt
  • Publication number: 20130336897
    Abstract: Macrophages sequester and aggregate ultrasmall superparamagnetic iron oxide nanoparticles (USPIO) in their lysosomes. The amount of USPIO loading of macrophages depends upon the route and dose of administration, and the pharmacokinetics of accumulation and removal. Both fixed macrophages and activated macrophages associated with inflammatory diseases and cancer phagocytize USPIOs, and the loaded macrophages can serve to identify the extent of a macrophage-dependent disease as well as to direct treatment options. Furthermore, the absorption of energy from incident electromagnetic waves by the aggregated nanoparticles can be used for conformal thermotherapy. The USPIOs can further be used to carry drugs to the same activated macrophages. The co-administered drugs can be bound to the USPIO by condition-dependent releasing links that are responsive to local pH or heating.
    Type: Application
    Filed: June 18, 2013
    Publication date: December 19, 2013
    Inventors: Gerald L. Wolf, Karl F. Schmidt
  • Patent number: 6104970
    Abstract: A crawler vehicle for inspection of the floor of a tank partially filled with a liquid includes telemetry carried by a tether between the vehicle and the remote station for communication of data and control signals between the vehicle and personnel within the station. The vehicle carries a Hall-effect sensor to sense anomalies in a magnetic flux outside the plate resulting from pitting within the plate. An array of ultrasonic transducer probes provides a detailed picture of the defect. A proximity sensor determines the presence of a step abutment between contiguous plates to command for a retraction of the magnet to prevent collision with the step abutment. A pressure sensor measures the depth between the vehicle and a planar surface of the liquid, used as a reference plane, to determine a degree of flatness of the floor and the presence of any settling of the floor.
    Type: Grant
    Filed: February 17, 1998
    Date of Patent: August 15, 2000
    Assignee: Raytheon Company
    Inventors: Karl F. Schmidt, Jr., Tagore Somers
  • Patent number: D795890
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: August 29, 2017
    Assignee: Biogen MA Inc.
    Inventors: Ajay Verma, John W. Hoppin, Karl F. Schmidt