Abstract: The invention relates to a bioreactor including a housing having a lower housing half and an upper housing half that are respectively connected to one another on one side by a film joint. At least one of the upper or lower housing halves includes a device to exchange fluids. The bioreactor further includes at least one support element to support at least one cell culture substrate. The invention furthermore relates to an arrangement of such bioreactors, processes for production thereof and use thereof for culturing cells or as an implant.

Abstract: In a process for rapidly and inexpensively diagnosing malignant diseases or their precursor stages, samples of arterial and/or capillary blood and of venous blood are withdrawn from a patient and the percentage shares of three groups of blood cells in the blood samples are determined wherein a first group includes blood cells of a size ≦8 &mgr;m, a second group includes blood cells of a 9 &mgr;m and 10 &mgr;m and the third group includes blood cells of a size ≧11 &mgr;m. The percentage shares are multiplied by weighting factors &agr;1 and &bgr;1, and the values y=&Sgr;&agr;i[(Ni)A]−&Sgr;&agr;i[(Ni)V] and x=&Sgr;&bgr;i[(Ni)A]−&Sgr;&bgr;i[(Ni)V], are calculated and from the locations of x and y in an x/y coordinate system, the presence of Ca. corp. uteri or its precursor stages is determined.

Abstract: In a method of diagnosing a malignant disorder or its precursor stage, the percentage parts N.sub.i of blood cells in a size range of i=6 .mu.m to i=16 .mu.m in two blood samples of a patient, an arterial or capillary blood sample (A) and a venous blood sample (V) are determined based on the total number of blood cells in the arterial or capillary blood sample and the venous blood sample, the values obtained thereby a multiplied by a weighting factor .alpha..sub.1 and are then summed up and from the sums A and V, respectively the values x=A+V and y=A-V are calculated and the deviation of the values x and y from the values x and y of a healthy person are determined for diagnosing the disorder.

Abstract: In an apparatus for culturing cells which comprises a plate-like body with a lattice structure having openings separated from one another by sidewalls and a bottom disposed on one side of the lattice structure and having passages permeable for liquids but not for cells so as to form, with the lattice structure, cavities for receiving cells to be grown therein, the cavities have a clear width of between 50 .mu.m and 1000 .mu.m and the bottom consists of a material to which cells placed into the cavities will not easily attach so that the cells grow from the side walls of the cavities causing them to form a three-dimensional cell structure.