Patents by Inventor Karl Georg Metzger

Karl Georg Metzger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-(Substituted-cycloalkylcarboxamide) penicillanic acids
    Patent number: 3954730
    Abstract: Penicillins of the formula ##SPC1##Or a pharmaceutically-acceptable, nontoxic salt thereof,WhereinR.sub.1 and R.sub.2 are the same or different and each is hydrogen, fluorine, chlorine or bromine; or when R.sub.2 is hydrogen, R.sub.1 can also be cyano, hydroxyl, azido, amino or nitro; orR.sub.1 and R.sub.2 are bonded to a ring carbon atom and constitute a single oxygen atom;R.sub.3 is hydrogen, methyl, chlorine, bromine, cyano, methoxy or carboxyl; andn is 2 to 7;Are useful for their antibacterial activity.
    Type: Grant
    Filed: October 21, 1974
    Date of Patent: May 4, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl Georg Metzger, Gunther Schmidt
  • Ureidoacetamido-penicillins
    Patent number: 3939149
    Abstract: 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
    Type: Grant
    Filed: December 19, 1973
    Date of Patent: February 17, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Bodo Konig, Wilfried Schrock, Hans Disselnkotter, Karl Georg Metzger
  • Ureidoacetamido-penicillins
    Patent number: 3933795
    Abstract: 6-(.alpha.-3-Acyl-unreidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.
    Type: Grant
    Filed: December 19, 1973
    Date of Patent: January 20, 1976
    Assignees: Hans-Bodo Konig, Wilfried Schrock, Bayer Aktiengesellschaft
    Inventors: Hans Disselnkotter, Karl Georg Metzger
  • Penicillins
    Patent number: 3931153
    Abstract: Penicillins of the formula: ##SPC1##And their pharmaceutically acceptable nontoxic salts whereinR.sub.1 is hydrogen, halogen, lower alkyl, hydroxy, nitro or A--NH;A is ##EQU1## wherein R.sub.3 is hydrogen; lower alkyl; halo-(lower alkyl); cycloalkyl of 3 to 11 carbon atoms, unsubstituted or substituted by hydroxy or alkyl of 1 or 2 carbon atoms; cycloalkenyl of 3 to 11 carbon atoms; bicycloalkyl of up to 8 carbon atoms; bicycloalkenyl of up to 8 carbon atoms; aryl of 6 to 10 carbon atoms, unsubstituted or substituted by 1 to 3 substituents selected from the group consisting of alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, halogen, trifluoromethyl, nitro, amino, alkylsulphonyl of 1 to 4 carbon atoms, and methylenedioxy; azidoaryl of 6 to 10 carbon atoms, azido-(lower alkyl); amino; or thienyl;R.sub.4 is lower alkylamino or arylamino of 6 to 10 carbon atoms;B is a direct bond; CH.sub.2 ; S--CH.sub.2 ; CH=CH; or CO--NH--CH.sub.
    Type: Grant
    Filed: November 29, 1973
    Date of Patent: January 6, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gunter Schmidt, Karl Georg Metzger