Patents by Inventor Karl Gerhardt

Karl Gerhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR INCREASED NUCLEIC ACID-GUIDED CELL EDITING
    Publication number: 20240076697
    Abstract: The present disclosure provides compositions of matter, methods, systems, and instruments for improved nucleic acid-guided nuclease editing in live cells, wherein the live cells are shifted into a growth-arrested state for editing.
    Type: Application
    Filed: August 31, 2023
    Publication date: March 7, 2024
    Applicant: Inscripta, Inc.
    Inventors: Karl GERHARDT, Charles JOHNSON, Martha BRAUN
  • LIGHT-CONTROLLED GENE DELIVERY WITH VIRUS VECTORS THROUGH INCORPORATION OF OPTOGENETIC PROTEINS AND GENETIC INSERTION OF NON-CONFORMATIONALLY CONSTRAINED PEPTIDES
    Publication number: 20190203227
    Abstract: This invention describes light-controlled delivery to the nucleus of target cells via viral vectors modified using optogenetic tools. This invention also describes tools for the display of proteins on the surface of adeno-associated virus using enzymatic tools to display the proteins in a more favorable thermodynamic configuration to enhance activity of the proteins or their targets.
    Type: Application
    Filed: March 21, 2018
    Publication date: July 4, 2019
    Inventors: Michelle Ho, Junghae Suh, Eric Gomez, Justin Judd, Jeffrey Tabor, Karl Gerhardt