Patents by Inventor Karl H. Beyer, Jr.

Karl H. Beyer, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition and method for treating diabetes
    Patent number: 6323203
    Abstract: A pharmaceutical composition for treating diabetes, contains more than 600 mg of a compound of formula (I): where Y is O; R is NHCONR4R5; or N═C(NR4R5)2. Also, another pharmaceutical composition for treating diabetes, contains a compound selected from the group consisting of compounds of formula (I): where Y is O; R is OH.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: November 27, 2001
    Inventor: Karl H. Beyer, Jr.
  • Method for controlling and/or lowering serum glucose and fatty acid concentrations and hypertensive blood pressure in non-insulin-dependent diabetic patients
    Patent number: 5801177
    Abstract: The present invention is a method of treating non-insulin-dependent diabetes mellitus comprising administering to a patient in need thereof a therapeutically effective amount of at least one compound of formula (I) for a period of time of more than 6 days: ##STR1## wherein Y is OR is OH, NHCONR.sup.4 R.sup.5, or N.dbd.C(NR.sup.4 R.sup.5).sub.2 ;R.sup.4 and R.sup.5 are each independently selected from the group consisting of hydrogen; C.sub.1-10 alkyl, straight or branched chain; aryl C.sub.1-14 alkyl; and mono- or disubstituted aryl C.sub.1-4 alkyl where the substituents are fluoro, chloro, bromo, iodo or C.sub.1-10 alkyl, straight or branched chain; R.sup.1 and R.sup.2 are each independent selected from the group consisting of hydrogen, amino, and mono- or di-substituted amino where the substituents are C.sub.1-10 alkyl, straight or branched chain C.sub.3-8, cycloalkyl; provided that R.sup.1 and R.sup.2 may not both be amino or substituted amino; and R.sup.
    Type: Grant
    Filed: December 14, 1995
    Date of Patent: September 1, 1998
    Inventor: Karl H. Beyer, Jr.
  • Method for controlling and/or lowering serum triglyceride and/or cholesterol levels in mammals
    Patent number: 5110817
    Abstract: A method for controlling and/or reducing a patient's serum cholesterol and/or triglyceride level is disclosed.
    Type: Grant
    Filed: January 31, 1990
    Date of Patent: May 5, 1992
    Inventor: Karl H. Beyer, Jr.
  • Pyrazinoylguanidine and derivatives thereof having few polar substituents and being useful as hyperuretic agents
    Patent number: 4952582
    Abstract: Hyperuretic agents of the formula: ##STR1## wherein Y is O or NH;R is OH; NHCONR.sup.4 R.sup.5 ; or N.dbd.C(NR.sup.4 R.sup.5).sub.2 ;R.sup.1 and R.sup.2 are amino, or mono- or disubstituted amino, provided that R.sup.1 and R.sup.2 may not both be amino or substituted amino;and R.sup.3 is hydrogen or halo;enhance renal excretion of urea, thereby lowering plasma urea concentration, and are therefore useful for treating hypertension, eclampsia, uremia, and similar disorders.
    Type: Grant
    Filed: August 23, 1988
    Date of Patent: August 28, 1990
    Inventor: Karl H. Beyer, Jr.
  • Method for controlling and/or lowering serum triglyceride and/or cholesterol levels in mammals
    Patent number: 4920123
    Abstract: A method for controlling and/or reducing a patient's serum cholesterol and/or triglyceride level is disclosed.
    Type: Grant
    Filed: October 21, 1988
    Date of Patent: April 24, 1990
    Inventor: Karl H. Beyer, Jr.
  • Antihypertensive hyperuretic and saluretic agent combinations
    Patent number: 4663322
    Abstract: Hyperuretic agents of the formula: ##STR1## wherein Y is O or NH;R is OH; NHCONR.sup.4 R.sup.5 ; or N.dbd.C(NR.sup.4 R.sup.5).sub.2 ;R.sup.1 and R.sup.2 are hydrogen, amino, or mono- or disubstituted amino, provided that R.sup.1 and R.sup.2 may not both be amino or substituted amino; andR.sup.3 is hydrogen or halo;in combination with saluretic agents such as hydrochlorothiazide; are useful for treating hypertension.
    Type: Grant
    Filed: October 29, 1985
    Date of Patent: May 5, 1987
    Inventor: Karl H. Beyer, Jr.
  • Hyperuretic agents
    Patent number: 4594349
    Abstract: Hyperuretic agents of the formula: ##STR1## wherein Y is O or NH;R is OH; NHCONR.sup.4 R.sup.5 ; or N.dbd.C(NR.sup.4 R.sup.5).sub.2 ;R.sup.1 and R.sup.2 are hydrogen, amino, or mono- or disubstituted amino, provided that R.sup.1 and R.sup.2 may not both be amino or substituted amino; andR.sup.3 is hydrogen or halo; enhance renal excretion of urea, thereby lowering plasma urea concentration, and are therefore useful for treating hypertension, eclampsia, uremia, and similar disorders.
    Type: Grant
    Filed: January 4, 1982
    Date of Patent: June 10, 1986
    Inventor: Karl H. Beyer, Jr.