Patents by Inventor Karl H. Buchel
Karl H. Buchel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5371065Abstract: Fungicidal and plant growth-regulating substituted azolylmethyloxiranes of the formula ##STR1## in which R.sup.1 stands for alkyl,R.sup.2 stands for alkyl,X stands for a nitrogen atom or the CH group,Y stands (or halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl and/or optionally substituted phenylalkoxy andm stands for the numbers 0, 1, 2 or 3,and addition products thereof with acids and metal salts.Type: GrantFiled: February 2, 1989Date of Patent: December 6, 1994Assignee: Bayer AktiengesellschaftInventors: Hans-Ludwig Elbe, Karl H. Buchel, Wilhelm Brandes, Stefan Dutzmann, Klaus Lurssen
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Patent number: 5141553Abstract: Compounds which are ether derivatives of substituted 1-hydroxyalkyl-azoles, of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R.sup.1 represents a substituted alkyl, optionally substituted cycloalkyl or optionally substituted phenyl radical or, if either A represents a nitrogen atom, or if A represents the CH group and at the same B represents oxygen or sulphur, R.sup.1 also represents an unsubstituted alkyl radical,R.sup.Type: GrantFiled: January 14, 1983Date of Patent: August 25, 1992Assignee: Bayer AktiengesellschaftInventors: Graham Holmwood, Erik Regel, Gerhard Jager, Karl H. Buchel, Paul-Ernst Frohberger, Wilhelm Brandes, Klaus Lurssen
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Patent number: 5097050Abstract: An oxirane of the formula ##STR1## in which Ar represents phenyl optionally substituted with from one to three halogen atoms,R represents alkyl having from 1 to 4 carbon atoms,X.sup.1 represents halogen,X.sup.2 represents hydrogen or halogen,X.sup.3 represents hydrogen or halogen,X.sup.4 represents hydrogen or halogen andn represents 0 to 1,useful as intermediates for the synthesis of fungicidal hydroxyalkinyl-azoles.Type: GrantFiled: February 14, 1991Date of Patent: March 17, 1992Assignee: Bayer AktiengesellschaftInventors: Reinhard Lantzcsh, Ernst Kysela, Karl H. Buchel, Stefan Dutzmann, Wilheim Brandes, Gerd Hanssler
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Patent number: 5089640Abstract: Plant growth-regulating and fungicidal compounds of the formula ##STR1## in which Ar represents optionally substituted aryl or optionally substituted heteroaryl,R.sup.1 represents hydrogen, alkyl, alkenyl, alkinyl, trialkylsilyl, optionally substituted phenylalkyl or an acyl radical,R.sup.2 represents halogen, cyano, thiocyano, alkylcarbonyloxy, alkylcarbonylthio or the groupings --X--R.sup.3 and --NR.sup.4 R.sup.5,R.sup.3 represents alkyl, cycloalkyl, alkenyl, alkinyl, hydroxyalkyl, alkylthioalkyl, carboxyalkyl, alkoxycarbonylalkyl, optionally substituted aryl, optionally substituted aralkyl or the radical of the formula ##STR2## R.sup.4 and R.sup.3 independently of one another represent hydrogen or alkyl, orR.sup.4 and R.sup.5, together with the nitrogen atom to which they are bonded, represent an optionally substituted cycloaliphatic ring which can contain further heteroatoms,X represents oxygen, sulphur, an SO group or an SO.sub.2 group, orR.sup.Type: GrantFiled: September 28, 1988Date of Patent: February 18, 1992Assignee: Bayer AktiengesellschaftInventors: Klaus Bockmann, Erik Regel, Karl H. Buchel, Klaus Lurssen, Jorg Konze, Wilhelm Brandes
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Patent number: 5059615Abstract: Antimycotically active 1-cyano- and 1-carboxamidocyclopropylazolylmethylcarbinols have now been found of the formula ##STR1## in which R.sup.1 represents hydrogen or represents alkyl or represents alkylcarbonyl,R.sup.2 represents cyano or represents a group of the formula ##STR2## R.sup.3 represents phenyl which is optionally substituted by halogen, straight-chain or branched alkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy or halogenoalkylthio, or by phenyl or phenoxy which, in turn, may be substituted by halogen or alkyl having up to 6 carbon atoms,X represents a nitrogen atom or the CH group,Y represents a bond or represents a group of the formula ##STR3## in which R.sup.4 and R.sup.5 are identical or different and denote hydrogen or alkyl and their pharmaceutically tolerated acid addition salts.Type: GrantFiled: November 1, 1989Date of Patent: October 22, 1991Assignee: Bayer AktiengesellschaftInventors: Burkhard Fugmann, Manfred Plempel, Klaus Stroech, Karl H. Buchel
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Patent number: 5025030Abstract: Novel hydroxyalkinyl-azolyl derivatives of the formula ##STR1## in which Ar represents optionally substituted aryl,R represents alkyl, optionally substituted aryl or optionally substituted aralkyl,X.sup.1 represents halogen,X.sup.2 represents hydrogen or halogen,X.sup.3 represents hydrogen or halogen,X.sup.4 represents hydrogen or halogen andn represents 0 or 1,and acid addition salts and metal salt complexes thereof, are outstandingly effective as fungicides.Type: GrantFiled: July 7, 1989Date of Patent: June 18, 1991Assignee: Bayer AktiengesellschaftInventors: Reinhard Lantzsch, Ernst Kysela, Karl H. Buchel, Stefan Dutzmann, Wilhelm Brandes, Gerd Hanssler
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Patent number: 5011850Abstract: The invention relates to compounds and their derivatives, said compounds being described herein as those of Formula (I). The compounds and compositions containing them are effective antimycotic agents and the invention includes methods for the use of said compounds and compositions.Type: GrantFiled: October 6, 1986Date of Patent: April 30, 1991Assignee: Bayer AktiengesellschaftInventors: Hans-Ludwig Elbe, Erik Regel, Karl H. Buchel, Klaus Schaller, Manfred Plempel
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Patent number: 4999440Abstract: Fungicidal hydroxyalkyl-triazdyl derivatives of the formula ##STR1## in which R represents a radical of the formula --CH.sub.2 --CH(CH.sub.3).sub.2, --(CH.sub.2).sub.4 --CH.sub.3, --(CH.sub.2).sub.5 --CH.sub.3, --(CH.sub.2).sub.6 --CH.sub.3, ##STR2## Z represents halogen, alkyl with 1 to 4 carbon atoms, halogenoalkyl with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkylthio with 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl or alkoximinimethyl with 1 to 4 carbon atoms in the alkoxy group andm represents the numbers 0, 1, 2 or 3,and addition products thereof with acids and metal salts. Intermediates of the formulas ##STR3## are also new.Type: GrantFiled: August 17, 1989Date of Patent: March 12, 1991Assignee: Bayer AktiengesellschaftInventors: Graham Holmwood, Udo Kraatz, Karl H. Buchel, Wilhelm Brandes, Stefan Dutzmann, Paul Reinecke
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Patent number: 4994480Abstract: Fungicidal substituted triazolylmethylcarbinols of the formula ##STR1## in which n stands for the numbers 0 or 1,Ar stands for optionally substituted phenyl or for optionally substituted naphthyl,R.sup.1 stands for hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkinyl, optionally substituted aralkyl, cycloalkyl or optionally substituted heteroarylalkyl,R.sup.2 stands for alkyl, cycloalkyl, cycloalkylalkyl or alkenyl,R.sup.3 stands for methyl andR.sup.4 stands for methyl orR.sup.3 and R.sup.4 together stand for ethane-1,2-diyl, and addition products thereof with acids and metal salts. Intermediates of the formulas ##STR2## in which R.sup.6 stands for alkyl having more than one carbon atom, cycloalkyl, cycloalkylalkyl or alkenyl, are also new.Type: GrantFiled: April 12, 1989Date of Patent: February 19, 1991Assignee: Bayer AktiengesellschaftInventors: Karl H. Buchel, Graham Holmwood, Gerd Hannsler, Wilhelm Brandes, Stefan Dutzmann
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Patent number: 4988382Abstract: Plant growth-regulating and fungicidal compounds of the formula ##STR1## in which Ar represents optionally substituted aryl or optionally substituted heteroaryl,R.sup.1 represents hydrogen, alkyl, alkenyl, alkinyl, trialkylsilyl, optionally substituted phenylalkyl or an acyl radical,R.sup.2 represents halogen, cyano, thiocyano, alkylcarbonyloxy, alkylcarbonylthio or the groupings --X--R.sup.3 and --NR.sup.4 R.sup.5,R.sup.3 represents alkyl, cycloalkyl, alkenyl, alkinyl, hydroxyalkyl, alkylthioalkyl, carboxyalkyl, alkoxycarbonylalkyl, optionally substituted aryl, optionally substituted aralkyl or the radical of the formula ##STR2## R.sup.4 and R.sup.5 independently of one another represent hydrogen or alkyl, orR.sup.4 and R.sup.5, together with the nitrogen atom to which they are bonded, represent an optionally substituted cycloaliphatic ring which can contain further heteroatoms,X represents oxygen, sulphur, an SO group or an SO.sub.2 group, orR.sup.Type: GrantFiled: December 28, 1989Date of Patent: January 29, 1991Assignee: Bayer AktiengesellschaftInventors: Klaus Bockmann, Erik Regel, Karl H. Buchel, Klaus Lurssen, Jorg Konze, Wilhelm Brandes
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Patent number: 4968712Abstract: Fungicidal 1,4-disubstituted 1-azolyl-3,3-dimethylbutane derivatives of the formula ##STR1## in which R.sup.1 represents hydrogen or halogen,R.sup.2 represents hydrogen or halogen,R.sup.3 represents hydrogen, halogen or trifluoromethoxy,R.sup.4 represents halogen, trifluoromethoxy, trifluoromethylthio, trifluoromethylsulphinyl, trifluoromethylsulphonyl, difluoromethoxy, difluorochloromethoxy, trifluorochloroethoxy, tetrafluoroethoxy, trifluoroethoxy, difluoromethylthio, trifluorochloroethylthio, tetrafuoroethylthio, difluoromethylsulphinyl, difluorochloromethylsulphinyl, trifluorochloroethylsulphinyl, tetrafluoroethylsulphinyl, difluoromethylsulphonyl, difluorochloromethylsulphonyl, trifluorochloroethylsulphonyl, tetrafluoroethylsulphonyl, difluorobromomethylthio, difluorobromomethylsulphinyl, difluorobromomethylsulphonyl or difluorochloromethylthio orR.sup.3 and R.sup.4 together represent alkylenedioxy substituted by halogen,R.sup.Type: GrantFiled: July 29, 1988Date of Patent: November 6, 1990Assignee: Bayer AktiengesellschaftInventors: Hans-Ludwig Elbe, Albrecht Marhold, Karl H. Buchel, Stefan Dutzmann, Paul Reinecke, Wilhelm Brandes, Gerhard Hanssler
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Patent number: 4960453Abstract: Fungicidal and plant growth-regulating hydroxyalkylazolyl derivatives of the formula ##STR1## in which Z represents halogen, alkyl with 1 to 4 carbon atoms, halogenoalkyl with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy with 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkylthio with 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl or alkoximinomethyl with 1 to 4 carbon atoms in the alkoxy group,X represents oxygen, sulphur or a CH.sub.2 group andm represents the number 0, 1, 2 or 3,and addition products thereof with acids and metal salts. Intermediates of the formulas ##STR2## are also new.Type: GrantFiled: May 5, 1988Date of Patent: October 2, 1990Assignee: Bayer AktiengesellschaftInventors: Graham Holmwood, Gerhard Jager, Karl H. Buchel, Wilhelm Brandes, Stefan Dutzmann, Gerd Hanssler
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Patent number: 4960456Abstract: Compounds which are substituted 1-hydroxyalkyl-azolyl derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents oxygen, sulphur or a CH.sub.2 group,R represents a substituted alkyl, and, in the case in which B represents sulphur, also represents an unsubstituted alkyl, optionally substituted cyclo-alkyl or optionally substituted phenyl group,Z represents a halogen atom or an alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy group, andm is 0, 1, 2 or 3,and the acid addition salts and metal salt complexes thereof, are new, are prepared as described and find use as fungicides and plant growth regulators.Type: GrantFiled: May 19, 1989Date of Patent: October 2, 1990Assignee: Bayer AktiengesellschaftInventors: Graham Holmwood, Erik Regel, Gerhard Jager, Karl H. Buchel, Klaus Lurssen, Paul-Ernst Frohberger, Wilhelm Brandes, Volker Paul
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Patent number: 4960781Abstract: Fungicidal bisazolyl-hydroxyalkyl derivatives of the formula ##STR1## in which Ar stands for optionally substituted aryl,X stands for a grouping --CH.sub.2 CH.sub.2 --, --OCH.sub.2 --, --SCH.sub.2 -- or --SH.dbd.CH--,Y stands for a nitrogen atom or the grouping CR.sup.3,R.sup.1, R.sup.2 and R.sup.3 stand for hydrogen, halogen or methyl, andn stands for the numbers 0, 1 or 2,and acid addition salts and metal salt complexes thereof. Intermediates of the formulas ##STR2## are also new.Type: GrantFiled: February 16, 1990Date of Patent: October 2, 1990Assignee: Bayer AktiengesellschaftInventors: Graham Holmwood, Wolfgang Kramer, Erik Regel, Hans L. Elbe, Karl H. Buchel, Stefan Dutzmann, Wilhelm Brandes, Paul Reinecke
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Patent number: 4945101Abstract: Hydroxyalkinyl-azolyl derivatives of the formula ##STR1## in which A is a nitrogen atom or the CH group,R is optionally substituted alkyl, cycloalkyl or phenyl,R.sup.1 is hydrogen, alkyl, alkenyl, alkinyl, or optionally substituted benzyl,R.sup.2 is hydrogen or methyl, andX is hydrogen, bromine or iodine,or addition products thereof with acids or metal salts exhibit fungicidal activity. Some intermediates therefor are also new.Type: GrantFiled: October 4, 1985Date of Patent: July 31, 1990Assignee: Bayer AktiengesellschaftInventors: Gerhard Jager, Klaus Bockmann, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger, Hans Scheinpflug
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Patent number: 4940798Abstract: A substituted azolylvinyl ketone or carbinol of the formula ##STR1## in which R.sup.1 represents optionally substituted cycloalkyl with 3 to 5 carbon atoms, substituted cyclohexyl or the grouping ##STR2## wherein R.sup.3 represents optionally substituted phenyl, alkenyl, alkinyl, cyano or the grouping --Z--R.sup.4,whereinR.sup.4 represents alkyl, halogenoalkyl, optionally substituted phenyl or optionally substituted phenylalkyl andZ represents O, S, SO or SO.sub.2,n represents a number from 0 to 2,R.sup.2 represents alkyl, alkenyl, alkinyl, in each case optionally substituted phenyl or phenylalkyl, or in each case optionally substituted cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, bicycloalkyl or bicycloalkenyl, but R.sup.2 does not represent optionally substituted phenyl at the same time as R.sup.1 represents optionally substituted cycloalkyl with 3 to 5 carbon atoms or substituted cyclohexyl or R.sup.Type: GrantFiled: September 24, 1987Date of Patent: July 10, 1990Assignee: Bayer AktiengesellschaftInventors: Hans-Ludwig Elbe, Wolf Reiser, Erik Regel, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes, Klaus Lurssen, Paul-Ernst Frohberger
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Patent number: 4935049Abstract: New substituted azolylmethylcarbinols of the formula ##STR1## in which Ar stands for optionally substituted aryl,Z stands for nitrogen or an CH group andR stands for alkyl, dialkylaminoalkyl, alkenyl, alkinyl, alkoxyalkyl, optionally substituted aralkyl, optionally substituted aryloxyalkyl, optionally substituted aryl or a radical of the formula ##STR2##whereinR.sup.1 stands for hydrogen, alkyl, alkenyl, alkinyl or cycloalkyl andR.sup.2 stands for hydrogen, alkyl, alkoxyalkyl, alkenyl, alkinyl, cycloalkyl, cycloalkylalkyl, for optionally substituted aryl or for optionally substituted aralkyl, orR.sup.1 and R.sup.2 together with the nitrogen atom to which they are bonded stand for an optionally substituted heterocyclic ring which cna optionally contain further heteroatoms,and acid addition salts and metal salt complexes thereof, and the use of the novel compounds as fungicides and plant growth regulators.Type: GrantFiled: October 7, 1988Date of Patent: June 19, 1990Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kramer, Erik Regel, Karl H. Buchel, Stefan Dutzmann, Wilhelm Brandes, Klaus Lurssen
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Patent number: 4921528Abstract: Plant growth-regulating and fungicidal compounds of the formula ##STR1## in which Ar represents optionally substituted aryl or optionally substituted heteroaryl,R.sup.1 represents hydrogen, alkyl, alkenyl, alkynyl, trialkylsilyl, optionally substituted phenylalkyl or an acyl radical,R.sup.2 represents halogen, cyano, thiocyano, alkylcarbonyloxy, alkylcarbonylthio or the groupings --X--R.sup.3 and --NR.sup.4 R.sup.5,R.sup.3 represents alkyl, cycloalkyl, alkenyl, alkynyl, hydroxyalkyl, alkylthioalkyl, carboxyalkyl, alkoxycarbonylalkyl, optionally substituted aryl, optionally substituted aralkyl or the radical of the formula ##STR2## R.sup.4 and R.sup.3 independently of one another represent hydrogen or alkyl, orR.sup.4 and R.sup.5, together with the nitrogen atom to which they are bonded, represent an optionally substituted cycloaliphatic ring which can contain further heteroatoms,X represents oxygen, sulphur, an SO group or an SO.sub.2 group, orR.sup.Type: GrantFiled: October 19, 1988Date of Patent: May 1, 1990Assignee: Bayer AktiengesellschaftInventors: Klaus Bockmann, Erik Regel, Karl H. Buchel, Klaus Lurssen, Jorg Konze, Wilhelm Brandes
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Patent number: 4921870Abstract: A fungicidally active substituted phenethyl-triazolyl derivative of the formula ##STR1## in which X.sup.1 and X.sup.2 each independently is halogen or halogenoalkyl, and one of them may also be hydrogen,Y is >C.dbd.N--O--R or >CH--O--R,R is phenoxyethyl which is optionally substituted in the phenyl part,or an addition product thereof with an acid or salt.Type: GrantFiled: May 5, 1988Date of Patent: May 1, 1990Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kramer, Hans-Joachim Knops, Karl H. Buchel, Paul Reinecke
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Patent number: 4917720Abstract: Azolyl ether ketones and alcohols of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently represents alkyl with more than one carbon atom, orR.sup.1 represents dichloromethyl, trichloromethyl, chlorovinyl or dichlorovinyl, andR.sup.2 represents alkyl,R.sup.3 represents alkyl,A represents the keto group or a CH(OH) grouping,Z represents a nitrogen atom or the CH group,X represents oxygen or sulfur andAr represents optionally substituted phenyl,or addition products thereof with acids and metal salts, are active against fungi and in regulating the growth of plants. New intermediates therefor are also shown.Type: GrantFiled: October 12, 1988Date of Patent: April 17, 1990Assignee: Bayer AktiengesellschaftInventors: Gerhard Jager, Manfred Jautelat, Wolfgang Kramer, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes, Gerd Hanssler, Klaus Lurssen