Patents by Inventor Karl H. Nollstadt

Karl H. Nollstadt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified glucans as anti-caries agent and method of use
    Patent number: 4430322
    Abstract: Certain glucans modify the biosynthetic route of extracellular polysaccharides involved in dental plaque development causing critical loss of adhesiveness. They interfere with the biosynthesis of cell-bound polysaccharides reducing and preventing agglutination of cells. They thus aid in the prevention of dental plaque formation or concomitant dental caries and periodontal disease.
    Type: Grant
    Filed: April 28, 1982
    Date of Patent: February 7, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Thomas H. Stoudt, Karl H. Nollstadt
  • Group B streptococcal capsular polysaccharides
    Patent number: 4413057
    Abstract: Group B Streptococcus type-specific polysaccharides types I.sub.1, I.sub.b, II and III have been obtained from strains grown in a modified soy bean and yeast medium. These polysaccharides are useful as active or passive streptococcal vaccines.
    Type: Grant
    Filed: March 16, 1981
    Date of Patent: November 1, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Dennis J. Carlo, Karl H. Nollstadt, Thomas H. Stoudt, Robert Z. Maigetter
  • Process of producing modified glucans as anti-caries agent
    Patent number: 4340673
    Abstract: Certain glucans modify the biosynthetic route of extracellular polysaccharides involved in dental plaque development causing critical loss of adhesiveness. They interfere with the biosynthesis of cell-bound polysaccharides reducing and preventing agglutination of cells. They thus aid in the prevention of dental plaque formation or concomitant dental caries and periodontal disease.
    Type: Grant
    Filed: November 7, 1980
    Date of Patent: July 20, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Thomas H. Stoudt, Karl H. Nollstadt
  • Oral hygiene enzymes and method for preparation
    Patent number: 4335101
    Abstract: Enzymes called cariogenanases, elaborated by microorganisms are isolated and characterized as polysaccharases capable of degrading cariogenan, a newly discovered glucan of dental plaque composed of .alpha.-(1.fwdarw.3) and .alpha.-(1.fwdarw.2) linkages. The enzymes are isolable from culture broths of various organisms by protein precipitation methods, and have utility as an anti-dental plaque agent, either as the sole enzymatic agent or in combination with dextranases and/or plaque dispersing proteases.
    Type: Grant
    Filed: June 21, 1973
    Date of Patent: June 15, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Thomas H. Stoudt, Karl H. Nollstadt