Patents by Inventor Karl-Heinz Kuck
Karl-Heinz Kuck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230335289Abstract: Provided herein are systems and methods for assessing health risk for a user from a combination of Artificial Intelligence, ECG data available from the user's smart watch or other smart device, and other biometric data and/or medical data provided from the user.Type: ApplicationFiled: February 7, 2023Publication date: October 19, 2023Inventor: Karl-Heinz KUCK
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Publication number: 20230270549Abstract: Coaptation-assist devices (20) are provided for treating a native atrioventricular valve. The coaptation-assist devices (20) include a ventricular anchor (30), which includes one or more wires (35), and which is configured to be positioned in a ventricle; and a neo-leaflet (32), which is supported by the ventricular anchor (30) and is configured to at least partially replace function of a target native leaflet of the native atrioventricular valve by providing a surface of coaptation (34) for one or more opposing native leaflets. In some configurations, the ventricular anchor (30) includes a proximal subannular anchor (54), which includes a digitate anchor (56) that is shaped so as to define a plurality of fingers (60) having a plurality of curved superior peaks (66) that point in a superior direction and engage a subannular surface of the target native leaflet. Other embodiments are also described.Type: ApplicationFiled: July 22, 2020Publication date: August 31, 2023Applicant: MTEX CARDIO AGInventors: Andrea GUIDOTTI, Monica TOCOHI, Karl Heinz KUCK, Michael BUTSCHEID, Yaniv MARMUR, Pietro GOZZOLI
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Publication number: 20220273433Abstract: A leaflet coaptation-assist device (920, 1020, 1120) is provided for promoting valve coaptation of leaflets (22) of an atrioventricular valve, the leaflet coaptation-assist device (920, 1020, 1120) including a coaptation-assist surface (964, 1064, 1164) and one or more tissue anchors, which are configured to anchor the leaflet coaptation-assist device (920, 1020, 1120) in place within the heart, such that the coaptation-assist surface (964, 1064, 1164) is located at or below the leaflet hinge line and contacts an atrial side of the leaflets (22) during ventricular systole, thereby enhancing leaflet coaptation. In some configurations, the one or more tissue anchors include one or more ventricular loops (988, 1088, 1188), which are configured to couple the leaflet coaptation-assist device (920, 1020, 1120) to the ventricular wall by radial force and friction. Other embodiments are also described.Type: ApplicationFiled: August 6, 2020Publication date: September 1, 2022Inventors: Karl-Heinz KUCK, Andrea GUIDOTTI, Pietro GOZZOLI
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Patent number: 11419719Abstract: A prosthetic valve coaptation assist device includes an anchor and a single valve assist leaflet. The anchor may be a supporting ring frame, brace or arc structure and will usually be radially self-expandable so that it can expand against surrounding natural or prosthetic tissue. The valve assist leaflet may be made of pericardium or other biological or artificial material and is shaped like the native target valve leaflet. The valve assist leaflet is typically sized larger than the target natural or prosthetic leaflet so that after implantation a significant overlap of the device body occurs.Type: GrantFiled: August 1, 2019Date of Patent: August 23, 2022Assignee: MTEx Cardio AGInventors: Jury Schewel, Karl-Heinz Kuck, Tom Saul
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Publication number: 20220096236Abstract: A coaptation-assist device (20, 120A, 120B, 120C, 320A, 320B, 420, 720) is provided for treating a native atrioventricular valve, including a loop-shaped ventricular anchor (30, 130, 330, 430, 730) which includes an anchor-loop wire loop (50, 150, 350, 450, 750), which defines at least a portion of a border of the loop-shaped ventricular anchor, and is configured to be positioned in a ventricle, extending between a ventricular apical area and a subannular surface of a target native leaflet, and to remain anchored in position against surrounding anatomy, including the subannular surface, a ventricular wall, and the ventricular apical area. A neo-leaflet (32, 132A, 132B, 132C, 332A, 332B, 332A, 332B, 432, 732) is supported by the loop-shaped ventricular anchor and is configured to at least partially replace function of the target native leaflet by providing a surface of coaptation (34, 434, 734) for one or more opposing native leaflets that oppose the target native leaflet. Other embodiments are also described.Type: ApplicationFiled: January 14, 2020Publication date: March 31, 2022Applicant: MTEX CARDIO AGInventors: Andrea GUIDOTTI, Karl Heinz KUCK, Michael BUTSCHEID, David ZARBATANY, Ricardo ROMAN, Idan TOBIS, Monica TOCCHI, Yaniv MARMUR
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Publication number: 20190350705Abstract: A prosthetic valve coaptation assist device includes an anchor and a single valve assist leaflet. The anchor may be a supporting ring frame, brace or arc structure and will usually be radially self-expandable so that it can expand against surrounding natural or prosthetic tissue. The valve assist leaflet may be made of pericardium or other biological or artificial material and is shaped like the native target valve leaflet. The valve assist leaflet is typically sized larger than the target natural or prosthetic leaflet so that after implantation a significant overlap of the device body occurs.Type: ApplicationFiled: August 1, 2019Publication date: November 21, 2019Inventors: Jury SCHEWEL, Karl-Heinz KUCK, Tom SAUL
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Patent number: 10143553Abstract: A heart valve annulus repair device having a tissue engaging member and a plurality of anchors. The tissue engaging member includes a loop of wire. Each of the anchors has a pointy front end and a back end and a slot that runs in a front-to-back direction. The anchors are distributed about the loop of wire with the front ends of the plurality of anchors facing the heart valve annulus and with the loop of wire passing through the slots. The device further includes means for implanting the anchors into the heart valve annulus tissue so that the tissue engaging member becomes affixed to the heart valve annulus.Type: GrantFiled: December 10, 2012Date of Patent: December 4, 2018Assignee: Cardiac Implants, LLCInventors: David Alon, Karl-Heinz Kuck
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Publication number: 20160331262Abstract: Disclosed are various embodiments of invasive and non-invasive systems for combined electrophysiological mapping and ablation of a patient's heart. An electrophysiological mapping system (EMS) is configured to operate in conjunction with a cardiac ablation system, which in an invasive embodiment may employ an ablation catheter configured for insertion inside the heart of the patient, and in a non-invasive embodiment may comprise a HIFU transducer. The EMS is programmed and configured to process ECG signals acquired from a patient's torso during the combined electrophysiological mapping and cardiac ablation procedure, and to produce on a display or monitor the real-time or near-real-time voxel-model-derived visual representation of one or more locations on the patient's heart where at least one scar has been created by the ablation device during the combined procedure.Type: ApplicationFiled: May 1, 2016Publication date: November 17, 2016Inventors: Karl-Heinz Kuck, Markus Haller, Joerg Stroebel, Michael Maier, Mikhail Tsiklauri, Michael Butscheidt, Walther Schulze
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Patent number: 9149320Abstract: The present invention advantageously provides a method and system for the improved isolation and corresponding treatment of tissue targeted for cryogenic or other thermal therapy to increase the thermal efficacy and thermal efficiency of the treatment. In particular, the present invention provides methods and systems for improved thermal treatment of target tissue, such as a pulmonary vein and/or regions of the left atrium by reducing the resistive forces and/or increased thermal energy experienced from blood flow exiting the pulmonary vein into the left atrium during treatment.Type: GrantFiled: February 2, 2009Date of Patent: October 6, 2015Assignee: Medtronic CryoCath LPInventors: Karl Heinz Kuck, Julian Chun, Feifan Ouyang, Nicolas Coulombe, Jean-Luc Pageard, Randy Jordan
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Patent number: 8987500Abstract: The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.Type: GrantFiled: July 29, 2013Date of Patent: March 24, 2015Assignee: Bayer CropScience AGInventors: Reiner Fischer, Thomas Bretschneider, Ernst Rudolf F. Gesing, Dieter Feucht, Karl-Heinz Kuck, Peter Lösel, Olga Malsam, Christian Arnold, Thomas Auler, Martin Jeffrey Hills, Heinz Kehne
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Publication number: 20140309730Abstract: A heart valve annulus repair device having a tissue engaging member and a plurality of anchors. The tissue engaging member includes a loop of wire. Each of the anchors has a pointy front end and a back end and a slot that runs in a front-to-back direction. The anchors are distributed about the loop of wire with the front ends of the plurality of anchors facing the heart valve annulus and with the loop of wire passing through the slots. The device further includes means for implanting the anchors into the heart valve annulus tissue so that the tissue engaging member becomes affixed to the heart valve annulus.Type: ApplicationFiled: December 10, 2012Publication date: October 16, 2014Inventors: David ALON, Karl-Heinz KUCK
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Patent number: 8748471Abstract: Novel 2-alkylcycloalk(en)ylcarboxamides of the formula (I) in which X, s, R1, L, R2 and A are as defined in the description, a plurality of processes for preparing these compounds and their use for controlling unwanted microorganisms, and also novel intermediates and their preparation.Type: GrantFiled: November 27, 2012Date of Patent: June 10, 2014Assignee: Bayer CropScience AGInventors: Ralf Dunkel, Hans-Ludwig Elbe, Jörg Nico Greul, Benoit Hartmann, Herbert Gayer, Thomas Seitz, Ulrike Wachendorff-Neumann, Peter Dahmen, Karl-Heinz Kuck
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Publication number: 20140039215Abstract: The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.Type: ApplicationFiled: July 29, 2013Publication date: February 6, 2014Applicant: Bayer Intellectual Property GmbHInventors: Reiner FISCHER, Thomas BRETSCHNEIDER, Ernst Rudolf F. GESING, Dieter FEUCHT, Karl-Heinz KUCK, Peter LÖSEL, Olga MALSAM, Christian ARNOLD, Thomas AULER, Martin Jeffrey HILLS, Heinz KEHNE
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Patent number: 8586783Abstract: The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.Type: GrantFiled: January 11, 2012Date of Patent: November 19, 2013Assignee: Bayer CropScience AGInventors: Reiner Fischer, Thomas Bretschneider, Ernst Rudolf F. Gesing, Dieter Feucht, Karl-Heinz Kuck, Peter Lösel, Olga Malsam, Christian Arnold, Thomas Auler, Martin Jeffrey Hills, Heinz Kehne
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Publication number: 20130018202Abstract: The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.Type: ApplicationFiled: January 11, 2012Publication date: January 17, 2013Applicant: Bayer CropScience AGInventors: Reiner Fischer, Thomas Bretschneider, Ernst Rudolf F. Gesing, Dieter Feucht, Karl-Heinz Kuck, Peter Lösel, Olga Malsam, Christian Arnold, Thomas Auler, Martin Jeffrey Hills, Heinz Kehne
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Patent number: 8344015Abstract: Novel 2-alkylcycloalk(en)ylcarboxamides of the formula (I) in which X, s, R1, L, R2 and A are as defined in the description, a plurality of processes for preparing these compounds and their use for controlling unwanted microorganisms, and also novel intermediates and their preparation.Type: GrantFiled: December 8, 2005Date of Patent: January 1, 2013Assignee: Bayer Cropscience AGInventors: Ralf Dunkel, Hans-Ludwig Elbe, Jörg Nico Greul, Benoit Hartmann, Herbert Gayer, Thomas Seitz, Ulrike Wachendorff-Neumann, Peter Dahmen, Karl-Heinz Kuck
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Patent number: 8314254Abstract: The present invention relates to novel intermediates used in the preparation of substituted spirocyclic ketoenols of the formula (I) in which W, X, Y, Z, A, B, D and G are as defined in the disclosure.Type: GrantFiled: May 25, 2010Date of Patent: November 20, 2012Assignee: Bayer CropScience AGInventors: Reiner Fischer, Thomas Bretschneider, Christoph Erdelen, Angelika Lubos-Erdelen, legal representative, Jorg Konze, Peter Losel, Mark Wilhelm Drewes, Dieter Feucht, Karl-Heinz Kuck, Ulrike Wachendorff-Neumann
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Publication number: 20120283545Abstract: Percutaneous endovascular delivery of cardiac prosthetic devices is described through deep vascular access. Specifically, minimally intrusive access is achieved at points in the vascular tree having a size not usually achievable with existing tools. Localizing guide wires having visualization markings enable controlled passage through the vascular system.Type: ApplicationFiled: December 5, 2011Publication date: November 8, 2012Inventors: Karl-Heinz Kuck, Amr Salahieh, Hans Valencia, Claudio Argento, Tom Saul
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Patent number: 8299047Abstract: Novel 2-alkylcycloalk(en)ylcarboxamides of the formula (I) in which X, s, R1, L, R2 and A are as defined in the description, a plurality of processes for preparing these compounds and their use for controlling unwanted microorganisms, and also novel intermediates and their preparation.Type: GrantFiled: June 30, 2011Date of Patent: October 30, 2012Assignee: Bayer Cropscience AGInventors: Ralf Dunkel, Hans-Ludwig Elbe, Jörg Nico Greul, Benoit Hartmann, Herbert Gayer, Thomas Seitz, Ulrike Wachendorff-Neumann, Peter Dahmen, Karl-Heinz Kuck
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Patent number: 8168566Abstract: The present invention relates to novel 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to a plurality of processes for the preparation and to their use as pesticides and/or herbicides and/or microbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted pyrazolidine-3,5-dione derivatives of the formula (I) and a crop plant compatibility-improving compound.Type: GrantFiled: January 31, 2011Date of Patent: May 1, 2012Assignee: Bayer CropScience AGInventors: Reiner Fischer, Thomas Bretschneider, Ernst Rudolf F. Gesing, Dieter Feucht, Karl-Heinz Kuck, Peter Lösel, Olga Malsam, Christian Arnold, Thomas Auler, Martin Jeffrey Hills, Heinz Kehne