Patent number: 6200935
Abstract: The invention relates to novel arylalkyl compounds of the general formula (I)
in which
m represents the numbers 0 to 5,
n represents the numbers 0 to 4,
Q represents O, S, SO or SO2,
R1 represents hydrogen or optionally substituted alkyl,
R2 represents hydrogen or optionally substituted alkyl,
X represents hydroxyl, mercapto, amino, hydroxyamino, nitro, formyl, carboxyl, cyano, carbamoyl, thiocarbamoyl, halogen, or represents an in each case optionally cyano-, halogen- or alkoxy-substituted radical from the series alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkylamino, dialkylamino, alkylcarbonyl or alkoxycarbonyl,
Y represents nitro, carboxyl, cyano, carbamoyl, thiocarbamoyl, halogen, or represents an in each case optionally cyano-, halogen- or alkoxy-substituted radical from the series alkyl, alkoxy, alkylthio, alkylsulphinyl or alkylsulphonyl, and
Z represents one of the groupings below
in which
R3, R4, R5, R6 and R7 are each as defined in the desc
Type:
Grant
Filed:
July 16, 1999
Date of Patent:
March 13, 2001
Assignee:
Bayer Aktiengesellschaft
Inventors:
Roland Andree, Mark-Wilhelm Drewes, Andreas Lender, Karl-Heinz Linker, Otto Schallner, Markus Dollinger
Patent number: 6172225
Abstract: The invention relates to a novel process for producing thereof hydroxyarenes of the general formula (I)
in which
n represents the numbers 1, 2, 3 or 4,
R represents cyano, carboxyl, formyl, nitro, halogen or represents alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkylcarbonyl or alkoxycarbonyl, each of which is optionally substituted, and
Z represents hydrogen, cyano, nitro, halogen, alkyl, halogenoalkyl, or represents monocyclic or bicyclic, saturated or unsaturated heterocyclyl, heterocyclylamino or heterocyclylimino, each of which is optionally substituted,
characterized in that halogenoarenes of the general formula (II)
in which
n, R and Z are each as defined above and
X represents halogen
are reacted with 3-hydroxy-propionitrile of the formula (III),
HO—CH2CH2—CN (III),
if appropriate in the presence of a reaction auxiliary and if appropriate in the presence of a diluent, at temperatures between 0° C. and 100° C.
Type:
Grant
Filed:
November 12, 1998
Date of Patent:
January 9, 2001
Assignee:
Bayer Aktiengesellschaft
Inventors:
Karl-Heinz Linker, Wilhelm Haas, Otto Schallner, Kurt Findeisen, Roland Andree, Mark Wilhelm Drewes
