Patents by Inventor Karl-Heinz Schlemmer

Karl-Heinz Schlemmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dicarboxylic Acid Derivatives and their Use
    Publication number: 20100029772
    Abstract: The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 17, 2006
    Publication date: February 4, 2010
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr, Dieter Lang
  • PYRAZOLOPYRIDINE, INDAZOLE, IMIDAZOPYRIDINE, IMIDAZOPYRIMIDINE, PYRAZOLOPYRAZINE AND PYRAZOLOPYRIDINE DERIVATIVES AS STIMULATORS OF GUANYLATE CYCLASE FOR CARDIOVASCULAR DISORDERS
    Publication number: 20100029653
    Abstract: The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: September 1, 2007
    Publication date: February 4, 2010
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Hartmut Schirok, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Friederike Stoll, Karl-Heinz Schlemmer
  • I-PHENY 1-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVES AND THEIR USE
    Publication number: 20100022537
    Abstract: This invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Application
    Filed: July 27, 2009
    Publication date: January 28, 2010
    Applicant: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenieh, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • 4-Chromenonyl-1,4-dihydropyridines and their use
    Publication number: 20100022484
    Abstract: The present application relates to novel 4-chromenonyl-1,4-dihydropyridines, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
    Type: Application
    Filed: July 12, 2006
    Publication date: January 28, 2010
    Inventors: Alexander Kuhl, Peter Kolkhof, Heike Heckroth, Karl-Heinz Schlemmer, Ingo Flamme, Santiago Gigueroa Perez, Heike Gielen-Haertwig, Rolf Grosser, Jens-Kerim Ergüden, Dieter Lang
  • 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS
    Publication number: 20100016323
    Abstract: The application claims a compound of the formula or a salt, a hydrate, or a hydrate of a salt thereof. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of erectile dysfunction.
    Type: Application
    Filed: September 29, 2009
    Publication date: January 21, 2010
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Ulrich Niewöhner, Maria Niewöhner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski
  • Iminooxazolidine Derivatives and Their Use
    Publication number: 20100004292
    Abstract: The present application relates to novel iminooxazolidine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular thromboembolic disorders.
    Type: Application
    Filed: August 26, 2006
    Publication date: January 7, 2010
    Applicant: Bayer HealthCare AG
    Inventors: Susanne Rohrig, Mario Jeske, Metin Akbaba, Elisabeth Perzborn, Christoph Gerdes, Karl-Heinz Schlemmer
  • Heterocyclic Substituted, Anellated Pyrazole Derivative and its uses
    Publication number: 20100004235
    Abstract: The present application relates to novel heterocyclyl-substituted fused pyrazole derivatives, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: April 17, 2007
    Publication date: January 7, 2010
    Applicant: BAYER HEALTHCARE AG
    Inventors: Hartmut Schirok, Nils Griebenow, Chantal Fürstner, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Karl-Heinz Schlemmer, Stefan Heitmeier, Friederike Stoll
  • Novel, Acyclically Substituted Furopyrimidine Derivatives and Use Thereof
    Publication number: 20090318475
    Abstract: The present application relates to novel, acyclically substituted furopyrimidine derivatives, methods for their production, their use for the treatment and/or prophylaxis of diseases and their use for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.
    Type: Application
    Filed: December 8, 2006
    Publication date: December 24, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Thomas Lampe, Eva-Maria Becker, Raimund Kast, Hartmut Beck, Mario Jeske, Joachim Schuhmacher, Friederike Stoll, Martina Klein, Metin Akbaba, Andreas Knorr, Johannes-Peter Stasch, Lars Bärfacker, Alexander Hillisch, Gunter Karig, Mark Meininghaus, Karl-Heinz Schlemmer, Rudolf Schohe-Loop
  • Difluorophenol Derivatives and Their Use
    Publication number: 20090291993
    Abstract: The present application relates to novel difluorophenol derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 9, 2006
    Publication date: November 26, 2009
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr
  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7592339
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: September 22, 2009
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Heterocyclic compounds with carboxyl isostere groups and their use for the treatment of cardiovascular diseases
    Publication number: 20090227640
    Abstract: The present application relates to novel heterocyclic compounds, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 9, 2006
    Publication date: September 10, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Klaus Münter, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder
  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7585860
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: September 8, 2009
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Substituted 2-oxo-3-phenyl-5-carbonylaminomethyl-1,3-oxazolines and their use as anticoagulant and antithrombotics
    Patent number: 7582666
    Abstract: The invention relates to the field of blood coagulation, more particularly, to novel compounds of general formula (I), to a method for producing the compounds and to their use as active ingredients in medicaments for the prevention and/or the treatment of diseases.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: September 1, 2009
    Assignee: Bayer Schering Pharma AG
    Inventors: Alexander Straub, Thomas Lampe, Josef Pernerstorfer, Elisabeth Perzborn, Jens Pohlmann, Susanne Rohrig, Karl-Heinz Schlemmer
  • Tetrazole Derivatives and Their Use for the Treatment of Cardiovascular Diseases
    Publication number: 20090215843
    Abstract: The present application relates to novel tetrazole derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 9, 2006
    Publication date: August 27, 2009
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr
  • 4-Chromenonyl-1,4-dihydropyridinecarbonitriles and the use thereof
    Publication number: 20090214675
    Abstract: The present application relates to novel 4-chromenonyl-1,4-dihydropyridinecarbonitriles, processes for their preparation, pharmaceutical compositions containing them, and their use for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.
    Type: Application
    Filed: July 14, 2006
    Publication date: August 27, 2009
    Applicant: Bayer HealthCare AG
    Inventors: Alexander Kuhl, Peter Kolkhof, Heike Heckroth, Karl-Heinz Schlemmer, Ingo Flamme, Santiago Figueroa Perez, Heike Gielen-Haertwig, Rolf Grosser, Jens-Kerim Ergüden, Dieter Lang
  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7576111
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: August 18, 2009
    Assignee: Bayer Schering Pharma AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • 1-phenyl1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use
    Patent number: 7566723
    Abstract: The invention relates to novel 1-Phenyl-3,4-dihydropyrimidin-2(1H)-one derivatives having the formula processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: July 28, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Heike Gielen-Haertwig, Volkhart Min-Jian Li, Ulrich Rosentreter, Karl-Heinz Schlemmer, Swen Allerheiligen, Leila Telan, Lars Bärfacker, Jörg Keldenich, Mary F. Fitzgerald, Kevin Nash, Barbara Albrecht, Dirk Meurer
  • 3,5-Difluoropyridines
    Patent number: 7514565
    Abstract: The invention relates to compounds of the formule
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: April 7, 2009
    Assignee: Bayer AG
    Inventors: Jürgen Stoltefuβ, Siegfried Goldmann, Thomas Krämer, Karl-Heinz Schlemmer, Ulrich Niewöhner, Maria Niewöhner, Arnold Paeβens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jörn Stölting
  • Isophthalic acid derivatives
    Patent number: 7498460
    Abstract: The present invention relates to isophthalic acid derivatives, to a process for their preparation and to their use for producing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular of cardiovascular disorders.
    Type: Grant
    Filed: November 28, 2003
    Date of Patent: March 3, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Michael Härter, Jens Ergüden, Frank Wunder, Hanna Tinel, Johannes Köbberling, Eva-Maria Becker, Klaus Münter, Karl-Heinz Schlemmer, Raimund Kast, Peter Kolkhof, Gunter Karig, Lars Bärfacker, Walter Hübsch, Joachim Schuhmacher, Susanne Zuleger, Arnel Concepcion, Haruka Shimizu
  • Substituted isoindoles and their use
    Patent number: 7482472
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: January 27, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer