Abstract: The invention discloses a method of treating an individual having a disorder responsive to PAF-antagonist activity by treating the individual with a compound of formula I or II ##STR1## wherein A is an anellated and optionally substituted benzene or 5- or 6-membered heterocyclic ring; R.sub.5 and Z are each independently hydrogen or an optionally substituted C.sub.1 -C.sub.8 alkyl, alkenyl or alkynyl; R.sub.6 is an optionally substituted phenyl, or is thienyl or is .alpha.-pyridyl; Y is CO, CS or CH.sub.2 ; and nontoxic, pharmaceutically acceptable acid addition salts thereof.

Abstract: The invention discloses a method of treating an individual having a disorder responsive to PAF-antagonist activity by treating the individual with a compound of formula I or II: ##STR1## wherein A is an annealed and optionally substituted benzene or 5- or 6-membered heterocyclic ring; B is an optionally substituted 5-membered heterocyclic ring; R.sub.5 and R.sub.7 are each independently hydrogen or an optionally substituted C.sub.1 -C.sub.8 alkyl, alkenyl or alkynyl; R.sub.6 is an optionally substituted phenyl, or is thienyl or .alpha.-pyridyl; and non-toxic, pharmaceutically acceptable acid addition salts thereof.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms; andR.sub.2 is pyridyl, phenyl or mono-, di- or tri-substituted phenyl, where the substituents are alkyl of 1 to 2 carbon atoms, alkoxy of 1 to 2 carbon atoms, fluorine, chlorine, bromine, trifluoromethyl, nitro, benzyloxy or hydroxyl.The compounds are useful as nootropics.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is amino, acetylamino, hydroxymethyl, methoxymethyl or ##STR2## R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, methoxy, methyl or ethyl;R.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.5 and R.sub.6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocyclic ring where, in the case of a 6-membered ring, a --CH.sub.2 -group in the ring may be replaced by an oxygen atom,and non-toxic, pharmacologically acceptable salts thereof. The compounds as well as their salts are useful as antidepressants.

Abstract: A control system for longwall mining roof supports which are controlled in dependence on the position of the mining machine at any time. All of the roof supports are connected to a central computer via common conductors. Each of the roof supports includes a control unit having a code corresponding to the number of that support. This code serves as an address and enables the central computer to transmit its control command signals positively, in response to the mining machine position signals, through an appropriate address control unit for a particular roof support. In order to enable roof supports to be actuated manually also, the control units of all of the roof supports are connected to the central computer by two common conductors, one of which carries an automatic enable signal and the other of which carries a manual enable signal.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms;R.sub.5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkenyl of 3 to 6 carbon atoms;R.sub.6 is alkyl of 1 to 6 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl, halo-phenyl, lower alkyl-phenyl, or lower alkoxy-phenyl or ##STR2## R.sub.7 and R.sub.8 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy or 1 to 6 carbon atoms;n is an integer from 0 to 4, inclusive;x is --O--, --S--, or --CH.sub.2 --; and the broken line between the 10 and 13b-positions indicates a single or double bond;and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as antiallergics and antithrombotics.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is amino, acetylamino, hydroxymethyl, methoxymethyl or ##STR2## R.sub.2 and R.sub.3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, methoxy, methyl or ethyl;R.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.5 and R.sub.6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, form a 5-, 6- or 7-membered heterocyclic ring where, in the case of a 6-membered ring, a --CH.sub.2 -group in the ring may be replaced by an oxygen atom, and non-toxic, pharmacologically acceptable salts thereof. The compounds as well as their salts are useful as antidepressants.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is chlorine, bromine or iodine,R.sub.2 is hydrogen or halogen, andR.sub.3 is hydrogen, lower alkyl or hydroxy-lower alkyl, or when R.sub.3 is hydrogen, an alkali metal salt thereof; the compounds and their salts are useful as anxiolytics, anticonvulsives and sedatives.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is chlorine, bromine or alkyl of 1 to 3 carbon atoms;R.sub.2 is hydrogen or, when R.sub.1 is alkyl, chlorine or bromine;R.sub.1 and R.sub.2, together with each other, are straight alkylene of 3 to 4 carbon atoms;R.sub.3 is hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 2 carbon atoms; hydroxyl or trifluoromethyl; andR.sub.4 is hydrogen, straight or branched alkyl of 1 to 4 carbon atoms or phenyl lower alkyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.

Abstract: Compounds of the formula ##STR1## wherein R.sub.2 is hydrogen, chlorine, bromine, formyl, acetyl, alkyl of 1 to 4 carbon atoms, nitro, cyano or --CH.sub.2 --A;whereA is (alkyl of 1 to 2 carbon atoms)-amino; di(alkyl of 1 to 2 carbon atoms)-amino, where one of the alkyl moieties may have a terminal hydroxyl substituent attached thereto; or a 5-, 6- or 7-membered saturated, nitrogen-containing heterocycle which is attached to the methylene group through the nitrogen atom and may have a hydroxyl or hydroxymethyl substituent attached to a ring carbon atom, and the 6-membered heterocycle may contain oxygen as an additional ring heteroatom in the p-position;R.sub.3 is hydrogen, fluorine, chlorine, bromine, methyl or methoxy; andR.sub.4 is hydrogen or alkyl of 1 to 3 carbon atoms;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.

Abstract: This invention relates to a compound of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, and R.sub.4, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl or alkoxy group of from 1 to 6 carbon atoms;R.sub.5 and R.sub.6, which may be the same or different, each represent a hydrogen atom, an alkyl group of from 1 to 6 carbon atoms, or an alkenyl group of from 3 to 6 carbon atoms, or R.sub.5 and R.sub.6 together with the nitrogen atom to which they are attached represent a pyrrolidino, piperidino, or morpholino group; andX represents oxygen, sulfur, or a methylene group,or a non-toxic, pharmacologically acceptable acid addition salt thereof, or a racemate, enantiomer, or mixture of enantiomers thereof. The compounds of Formula I are useful in pharmaceutical compositions for treating bronchial asthma and allergic bronchitis.

Abstract: Compounds of the steroisomeric formulas ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each phenyl, substituted phenyl, thienyl or furyl;R.sub.3 is hydrogen or straight or branched alkyl of 1 to 3 carbon atoms; andR.sub.4 is straight or branched alkyl of 1 to 3 carbon atoms; orR.sub.3 and R.sub.4, together with each other and the nitrogen atom to which they are attached, form a piperidino, 4-amino-piperidino, 4-(lower alkylamino)-piperidino, piperazino, 4-(alkyl of 1 to 2 carbon atoms)-piperazino or morpholino radical; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as antidepressants.

Abstract: A cable extending onto a drum-cutter loader mining machine has divided branch cable sections to supply electrical current to the individual drive motors for each of two cutting drums. A branch switch coupled in each divided branch cable section and a thyristor controller is coupled in one branch cable section before the switch therein. Crossover lines bridge the branch switches in each divided branch cable section. Bridge switches in each of the bridging crossover lines are used together with the branch switches to deliver electrical current from the controller to either or, if desired, both of the separate drive motors.

Abstract: A signal is generated which varies with the distance between a mining machine and a cable trolley coupled by a rope to a winch disposed toward the lower drift of an inclined mine seam. The cable trolley moves along the face of the mine seam to guide and loop a trailing cable and/or water hose extending onto the mining machine. The winch is controlled in response to the signal for exerting tension inversely proportional to the distance between the cable trolley and the mining machine. The winch is driven by an electric torque motor or a hydraulic motor. In a further embodiment, the signal which is generated to control the winch varies the pull by the trailing cable and/or water hose upon the mining machine. This signal is used for controlling the winch in the same manner, namely, inversely proportional to the distance between the cable trolley and the mining machine.

Abstract: Mining equipment of the type operably dependent on the voltage and/or the phase of electric current is isolated from electric supply mains by an OFF switch in a control circuit before a current supply relay drops out. The OFF switch and an ON switch are coupled in a monitoring conductor which supplies current to a photo-electronic coupler. An output signal from the coupler is delivered to a battery fed integrator to provide a control signal to an output relay for a switch in the current supply line on mining equipment. The ON switch is bridged by a normally closed switch coupled to a relay which is responsive to operating current fed to the machine. In a second embodiment, thermal sensing elements for motor windings on the machine provide a signal to battery fed relays to open a normally closed switch in a circuit bridging the photo-electronic coupler.

Abstract: A multiple-step process for the preparation of 6-aryl-4H-s-triazolo-[3,4-c]-thieno-[2,3-e]-1,4-diazepines of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen or lower alkyl of 1 to 2 carbon atoms;R.sub.2 is hydrogen, chlorine, bromine, straight or branched alkyl of 1 to 3 carbon atoms, .omega.-hydroxyalkyl of 1 to 3 carbon atoms, cycloalkyl of 3 to 6 carbon atoms or a 5- or 6-membered heterocycle comprising an oxygen sulfur or nitrogen atom, where the nitrogen atom may optionally be substituted by lower alkyl; andR.sub.3 is hydrogen, fluorine, chlorine, or bromine;and optionally acid addition salts thereof, starting from compounds of the formula ##STR2## wherein R.sub.1 and R.sub.3 have the meanings defined above, andX is halogen, amino or acyloxy.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, chlorine, bromine or alkyl of 1 to 4 carbon atoms;R.sub.2 is hydrogen, fluorine, chlorine, bromine, nitro or trifluoromethyl; andR.sub.3 is chlorine, bromine, alkoxy of 1 to 3 carbon atoms, alkylmercapto of 1 to 3 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, cycloalkenyl of 3 to 6 carbon atoms, or a saturated or unsaturated 5- to 6-membered heterocycle comprising an oxygen, sulfur or nitrogen heteroatom, where a substitutable nitrogen heteroatom may optionally have a lower akyl substituent attached thereto;and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as tranquilizers, muscle-relaxants and anticonvulsants.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkyl, halo-lower alkyl, hydroxy-lower alkyl, di(lower alkyl)amino-lower alkyl, phenyl, tolyl, methoxy-phenyl, nitro-phenyl, halo-phenyl, pyridyl, pyrimidinyl or --CO--R.sub.4, where R.sub.4 is hydrogen, alkyl or 1 to 17 carbon atoms, alkoxy of 1 to 2 carbon atoms, phenyl, tolyl, methoxy-phenyl, halo-phenyl, nitro-phenyl or pyridyl;R.sub.2 is hydrogen, fluorine, chlorine, or bromine; andR.sub.3 is chlorine, bromine or lower alkyl,and non-toxic, pharmacologically acceptable acid addition salts of certain of these compounds. The compounds as well as the salts are useful as anxiolytics, tranquilizers, sedatives or neuroleptics.

Abstract: A feeler for measuring lengths operable in a controlled measuring direction provided as an additional device for two-coordinates measuring heads. The feeler includes a feeler lever which has one end designed as a circular feeler tip for feeling engagement with the workpiece to be measured. The feeler is mounted in a bi-valent joint on a base plate carried by the measuring head which joint permits a displacement of the feeler tip in the measuring plane in any desired direction. The other end of the feeler lever is linked to a straight line guide which is mounted on a disc arranged on the base plate so as to be rotatable by any desired angle about an axis extending in a direction perpendicular to the measuring plane. At the above mentioned other end the feeler lever is subjected to a measuring force which acts in the direction of the straight line guide. The disc has connected thereto an indicator for measuring the displacement of the above mentioned other end.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is alkyl of 1 to 6 carbon atoms, phenyl, substituted phenyl or heteroaryl;R.sub.2 is hydrogen or alkyl; andR.sub.3 is hydrogen, methyl, methoxy or halogen;And non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds are useful as neuroleptics.