Patents by Inventor Karl Heusler

Karl Heusler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene compounds
    Patent number: 4735937
    Abstract: The invention concerns 7-amino-ceph-3-em-4-carboxylic acid compounds of the formula ##STR1## wherein R.sub.1.sup.a represents hydrogen or an amino protective group R.sub.1.sup.A and R.sub.1.sup.b represent hydrogen or an acyl group AC, or R.sub.1.sup.A and R.sub.1.sup.b together denote a bivalent amino protective group, and R.sub.2 represents hydrogen or an organic radical R.sub.2.sup.A which together with the --C(.dbd.O)--O-- grouping forms a protected carboxyl group, or salts such compounds which possess salt-forming groups; these compounds have antibiotic properties.
    Type: Grant
    Filed: March 28, 1986
    Date of Patent: April 5, 1988
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Karl Heusler, Hans Bickel, Bruno Fechtig, Heinrich Peter, Riccardo Scartazzini
  • 8-Oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene compounds
    Patent number: 4430498
    Abstract: The invention concerns 7-amino-ceph-3-em-4-carboxylic acid compounds of the formula ##STR1## wherein R.sub.1.sup.a represents hydrogen or an amino protective group R.sub.1.sup.A and R.sub.1.sup.b represent hydrogen or an acyl group Ac, or R.sub.1.sup.A and R.sub.1.sup.b together denote a bivalent amino protective group, and R.sub.2 represents hydrogen or an organic radical R.sub.2.sup.A which together with the --C(.dbd.O)--O-- grouping forms a protected carboxyl group, or salts such compounds which possess salt-forming groups; these compounds have antibiotic properties.
    Type: Grant
    Filed: January 23, 1981
    Date of Patent: February 7, 1984
    Assignee: Ciba-Geigy Corporation
    Inventors: Karl Heusler, Hans Bickel, Bruno Fechtig, Heinrich Peter, Riccardo Scartazzini
  • Mercaptoalcohols and process for their manufacture
    Patent number: 4172832
    Abstract: The invention concerns 3-amino-4-(2-hydroxyethylthio)-2-oxo-azetidine compounds of the formula ##STR1## wherein R.sub.1.sup.a represents hydrogen or an amino protective group R.sub.1.sup.A, R.sub.1.sup.b represents hydrogen or an acyl group Ac.sub.1, or R.sub.1.sup.a and R.sub.1.sup.b together denote a bivalent amino protective group, R.sub.2 represents hydrogen or an acyl radical Ac.sub.2, and each of the radicals R.sub.3 and R.sub.4 represents hydrogen or an organic radical bonded via a carbon atom, or salts of such compounds having salt-forming groups.
    Type: Grant
    Filed: December 11, 1973
    Date of Patent: October 30, 1979
    Assignee: Ciba-Geigy Corporation
    Inventors: Riccardo Scartazzini, Hans Bickel, Karl Heusler
  • .alpha.-Halo-2-oxo-1-azetidinemethane-carboxylic acid compounds
    Patent number: 4161476
    Abstract: .alpha.-Hydroxy-2-oxo-1-azetidinemethane-carboxylic acid compounds of formula ##STR1## wherein R.sub.1 represents a hydrogen atom or the organic residue of an alcohol, R.sub.2 represents a hydrogen atom or an acyl residue, R.sub.3 represents an organic residue and R.sub.4 represents a hydrogen atom, when R.sub.2 stands for an acyl residue, or the two groups R.sub.3 and R.sub.4 together represent a disubstituted carbon atom, when R.sub.2 stands for a hydrogen atom or an acyl group, are useful as intermediates for the manufacture of pharmacologically active compounds.
    Type: Grant
    Filed: July 11, 1977
    Date of Patent: July 17, 1979
    Assignee: Ciba-Geigy Corporation
    Inventors: Karl Heusler, Robert B. Woodward
  • Oxyacetic acid compounds and process for their manufacture
    Patent number: 4052408
    Abstract: .alpha.-Hydroxy-2-oxo-1-azetidinemethane-carboxylic acid compounds of formula ##STR1## wherein R.sub.1 represents a hydrogen atom or the organic residue of an alcohol, R.sub.2 represents a hydrogen atom or an acyl residue, R.sub.3 represents an organic residue and R.sub.4 represents a hydrogen atom, when R.sub.2 stands for an acyl residue, or the two groups R.sub.3 and R.sub.4 together represent a disubstituted carbon atom, when R.sub.2 stands for a hydrogen atom or an acyl group, are useful as intermediates for the manufacture of pharmacologically active compounds.
    Type: Grant
    Filed: November 18, 1974
    Date of Patent: October 4, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Karl Heusler, Robert Burns Woodward