Abstract: This disclosure relates to the field of therapeutic RNAs for treatment of subjects that have failed, or become intolerant, resistant, or refractory to an anti-programmed cell death 1 (PD-1) or anti-programmed cell death 1 ligand 1 (PD-L1) therapy, including innate and acquired PD-1 and/or PD-L1 therapy, as well as in subjects with advanced-stage, unresectable, or metastatic solid tumor cancers with or without failure, intolerance, resistance, or refraction to an anti-programmed cell death 1 (PD-1) or anti-programmed cell death 1 ligand 1 (PD-L1) therapy.

Abstract: This disclosure relates to the field of therapeutic RNAs for treatment of subjects that have failed, or become intolerant, resistant, or refractory to an anti-programmed cell death 1 (PD-1) or anti-programmed cell death 1 ligand 1 (PD-L1) therapy, including innate and acquired PD-1 and/or PD-L1 therapy, as well as in subjects with advanced-stage, unresectable, or metastatic solid tumor cancers with or without failure, intolerance, resistance, or refraction to an anti-programmed cell death 1 (PD-1) or anti-programmed cell death 1 ligand 1 (PD-L1) therapy.

Abstract: Systems and methods for improving automatic selection of keeper images from a commonly captured set of images are described. A combination of image type identification and image quality metrics may be used to identify one or more images in the set as keeper images. Image type identification may be used to categorize the captured images into, for example, three or more categories. The categories may include portrait, action, or “other.” Depending on the category identified, the images may be analyzed differently to identify keeper images. For portrait images, an operation may be used to identify the best set of faces. For action images, the set may be divided into sections such that keeper images selected from each section tell the story of the action. For the “other” category, the images may be analyzed such that those having higher quality metrics for an identified region of interest are selected.

Abstract: Exemplary methods, apparatuses, and systems determine that an indication that a received message was sent in response to another message is present in the received message, parse a stored message, in response to the indication being present, for at least a partial match between a subject of the received message and contents of a subject of the stored message, and for at least a partial match between sender and recipient participants of the received message and sender and recipient participants of the stored message, and display the received message as grouped with the stored message. A further exemplary feature includes parsing text of the received message for text that is redundant of text of the stored message, determining that a minimum threshold of consecutive matching characters has been reached, and displaying the received message with the consecutive matching characters at least partially hidden from view.

Abstract: Systems and methods for improving automatic selection of keeper images from a commonly captured set of images are described. A combination of image type identification and image quality metrics may be used to identify one or more images in the set as keeper images. Image type identification may be used to categorize the captured images into, for example, three or more categories. The categories may include portrait, action, or “other.” Depending on the category identified, the images may be analyzed differently to identify keeper images. For portrait images, an operation may be used to identify the best set of faces. For action images, the set may be divided into sections such that keeper images selected from each section tell the story of the action. For the “other” category, the images may be analyzed such that those having higher quality metrics for an identified region of interest are selected.

Abstract: Systems and methods for improving automatic selection of keeper images from a commonly captured set of images are described. A combination of image type identification and image quality metrics may be used to identify one or more images in the set as keeper images. Image type identification may be used to categorize the captured images into, for example, three or more categories. The categories may include portrait, action, or “other.” Depending on the category identified, the images may be analyzed differently to identify keeper images. For portrait images, an operation may be used to identify the best set of faces. For action images, the set may be divided into sections such that keeper images selected from each section tell the story of the action. For the “other” category, the images may be analyzed such that those having higher quality metrics for an identified region of interest are selected.

Abstract: Methods of treating patients with cancer are provided, wherein the methods comprise administering to the patient an effective amount of a MEK inhibitor and an effective amount of a PI3K inhibitor. Compositions in which the MEK and PI3K inhibitors are combined also are described.

Abstract: The present invention provides, in part, compositions including an anti-IGF1R antibody or antigen-binding fragment thereof and any one or more of cisplatin, pemetrexed, gemcitabine and/or irinotecan; optionally including or excluding a further chemotherapeutic agent, as well as methods of treating diseases, such as cancer, using such compositions.

Abstract: An embodiment of the invention is directed to a method and apparatus for automatically providing network services in a way that improves upon the prior art. Systems implementing aspects of the invention can, for instance, provide developers with a mechanism for creating Web Services without having to write low-level SOAP, XML, or WSDL code. The system utilizes a rule-based approach to provide a mechanism for dynamically reconfiguring the system with requiring redeployment of the entire system.

Abstract: Exemplary methods, apparatuses, and systems determine that an indication that a received message was sent in response to another message is present in the received message, parse a stored message, in response to the indication being present, for at least a partial match between a subject of the received message and contents of a subject of the stored message, and for at least a partial match between sender and recipient participants of the received message and sender and recipient participants of the stored message, and display the received message as grouped with the stored message. A further exemplary feature includes parsing text of the received message for text that is redundant of text of the stored message, determining that a minimum threshold of consecutive matching characters has been reached, and displaying the received message with the consecutive matching characters at least partially hidden from view.

Abstract: An embodiment of the invention is directed to a method and apparatus for automatically providing network services in a way that improves upon the prior art. Systems implementing aspects of the invention can, for instance, provide developers with a mechanism for creating Web Services without having to write low-level SOAP, XML, or WSDL code. The system utilizes a rule-based approach to provide a mechanism for dynamically reconfiguring the system with requiring redeployment of the entire system.

Abstract: An embodiment of the invention is directed to a method and apparatus for automatically providing network services in a way that improves upon the prior art. Systems implementing aspects of the invention can, for instance, provide developers with a mechanism for creating Web Services without having to write low-level SOAP, XML, or WSDL code. The system utilizes a rule-based approach to provide a mechanism for dynamically reconfiguring the system with requiring redeployment of the entire system.

Abstract: An embodiment of the invention is directed to a method and apparatus for automatically providing network services in a way that improves upon the prior art. Systems implementing aspects of the invention can, for instance, provide developers with a mechanism for creating Web Services without having to write low-level SOAP, XML, or WSDL code. The system utilizes a rule-based approach to provide a mechanism for dynamically reconfiguring the system with requiring redeployment of the entire system.