Patents by Inventor Karl Kadler

Karl Kadler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified peptides and their uses
    Patent number: 7741279
    Abstract: A modified pro-? chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-? chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecule may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: June 22, 2010
    Inventors: Karl Kadler, Neil Bulleid, Gillian Ashcroft
  • MODIFIED PEPTIDES AND THEIR USES
    Publication number: 20080234176
    Abstract: A modified pro-? chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-? chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecule may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.
    Type: Application
    Filed: November 19, 2007
    Publication date: September 25, 2008
    Inventors: Karl Kadler, Neil Bulleid, Gillian Ashcroft
  • Modified pro-? peptides and their uses
    Patent number: 7351552
    Abstract: A modified pro-? chain comprising a triple helix forming domain linked to a polypeptide from at least part of a laminin glycoprotein. The pro-? chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecules may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.
    Type: Grant
    Filed: April 21, 2004
    Date of Patent: April 1, 2008
    Assignee: The University of Manchester
    Inventors: Karl Kadler, Neil Bulleid, Gillian Ashcroft
  • Modified peptides and their uses
    Publication number: 20070031478
    Abstract: A modified pro-? chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-? chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecules may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.
    Type: Application
    Filed: April 21, 2004
    Publication date: February 8, 2007
    Inventors: Karl Kadler, Neil Bulleid, Gillian Ashcroft
  • Procollagens
    Patent number: 6171827
    Abstract: There is disclosed molecules comprising at least a first moiety having the activity of a procollagen C-propeptide and a second moiety selected from any one of the group of an alien collagen &agr;-chain and non-collagen materials, the first moiety being attached to the second moiety. Also disclosed are collagen molecules, fibrils and fibres comprising a non-natural combination of collagen &agr;-chains, DNA encoding same, expression hosts transformed or transfected with same, transgenic animals and methods of producing a non-natural collagen.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: January 9, 2001
    Assignee: The Victoria University of Manchester
    Inventors: Neil Bulleid, Karl Kadler