Abstract: To provide a ceramic particle separable composite material having a calcium phosphate sintered body particle with which bioaffinity reduction and solubility change are suppressed as much as possible and which has a smaller particle diameter. A ceramic particle separable composite material comprising a ceramic particle and a substrate, wherein: the ceramic particle and the substrate are chemically bonded to each other, or the ceramic particle physically adheres to or is embedded in the substrate; the ceramic particle has a particle diameter within a range of 10 nm to 700 nm; the ceramic particle is a calcium phosphate sintered body particle; and the ceramic particle contains no calcium carbonate.

Abstract: This invention provides a measure that makes it possible to prevent more effectively, in comparison with the prior art, the invasion of germs from the gap between a dental prosthesis and the gingiva when the dental prosthesis is used in an oral cavity as well as the infection and inflammation associated therewith. There is a dental prosthesis or a component thereof, characterized in that: the dental prosthesis or the component thereof has hydroxyapatite fine particles on a surface of the dental prosthesis or the component thereof; the hydroxyapatite fine particles are sintered bodies; and the hydroxyapatite fine particles have a mean particle size of 10 to 1,000 nm.

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter. There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

Abstract: To provide a technology for sintering calcium phosphate to manufacture a calcium phosphate sintered body and suppressing generation of calcium oxide when calcium phosphate is sintered, there is provided a process for manufacturing a sintered calcium phosphate molded body is characterized by including a step for heating a composition containing at least a composite of calcium phosphate fine particles and polyether and sintering the calcium phosphate fine particles.

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter. There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

Abstract: It is an object of the present invention to provide a ceramic particle carrying medical tube and/or cuff excellent in cell adhesive property and the like. A medical tube and/or cuff carrying a ceramic particle in at least a part thereof, wherein: the ceramic particle has a particle diameter within a range of 10 nm to 700 nm; the ceramic particle is a calcium phosphate sintered body particle; and the ceramic particle contains no calcium carbonate.

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter. There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

Abstract: An inner surface-modified tube includes fine particles that are buried in an inner surface of a tube with part of surfaces of the fine particles exposed, wherein the fine particles are unevenly distributed such that more fine particles are distributed in a region from a center of the tube to the inner surface of the tube than in a region from the center of the tube to an outer surface of the tube based on a thickness direction of the tube, an arithmetic average roughness Ra of the inner surface of the tube is 1 nm or more and 100 ?m or less, a particle diameter of each fine particle is 10 nm or more and 100 ?m or less, and an inner diameter of the tube is 0.01 mm or more and 100 mm or less.

Abstract: To provide a novel stent which is excellent in cell adhesive property and the like. A stent carrying a ceramic particle, wherein: the ceramic particle has a particle diameter within a range of 10 nm to 700 nm; the ceramic particle is a calcium phosphate sintered body particle; and the ceramic particle contains no calcium carbonate.

Abstract: To provide a ceramic particle separable composite material having a calcium phosphate sintered body particle with which bioaffinity reduction and solubility change are suppressed as much as possible and which has a smaller particle diameter. A ceramic particle separable composite material comprising a ceramic particle and a substrate, wherein: the ceramic particle and the substrate are chemically bonded to each other, or the ceramic particle physically adheres to or is embedded in the substrate; the ceramic particle has a particle diameter within a range of 10 nm to 700 nm; the ceramic particle is a calcium phosphate sintered body particle; and the ceramic particle contains no calcium carbonate.

Abstract: To provide a technology for sintering calcium phosphate to manufacture a calcium phosphate sintered body and suppressing generation of calcium oxide when calcium phosphate is sintered, there is provided a process for manufacturing a sintered calcium phosphate molded body is characterized by including a step for heating a composition containing at least a composite of calcium phosphate fine particles and polyether and sintering the calcium phosphate fine particles.

Abstract: This invention provides a measure that makes it possible to prevent more effectively, in comparison with the prior art, the invasion of germs from the gap between a dental prosthesis and the gingiva when the dental prosthesis is used in an oral cavity as well as the infection and inflammation associated therewith. There is a dental prosthesis or a component thereof, characterized in that: the dental prosthesis or the component thereof has hydroxyapatite fine particles on a surface of the dental prosthesis or the component thereof; the hydroxyapatite fine particles are sintered bodies; and the hydroxyapatite fine particles have a mean particle size of 10 to 1,000 nm.

Abstract: Provided is an improved biocompatible immune adjuvant. More specifically, provided are: an immune adjuvant that comprises calcium phosphate, preferably hydroxyapatite, having an average particle size of about 40 nm exclusive to about 1800 nm exclusive; a medicine that comprises this immune adjuvant; and a vaccine that comprises this immune adjuvant. Rod-shaped HAp induced inflammasome-dependent IL-1? production in vitro more strongly than spherical HAp. In WT mice, however, spherical HAp and rod-shaped HAp induced equivalent antigen responses.

Abstract: To provide a method for producing a porous calcium phosphate body having open micro-pores, by the method for producing the porous calcium phosphate body, in which calcium phosphate is subjected to electro-spinning.

Abstract: A method for repairing a tooth surface having scratches and hollow portions formed on a tooth enamel surface includes administering a tooth surface repairing material to a dental disease patient. The tooth surface repairing material contains a highly crystalline sintered fine calcium phosphate particle having an average particle diameter in the range of 20 to 100 nm.

Abstract: An inner surface-modified tube includes fine particles that are buried in an inner surface of a tube with part of surfaces of the fine particles exposed, wherein the fine particles are unevenly distributed such that more fine particles are distributed in a region from a center of the tube to the inner surface of the tube than in a region from the center of the tube to an outer surface of the tube based on a thickness direction of the tube, an arithmetic average roughness Ra of the inner surface of the tube is 1 nm or more and 100 ?m or less, a particle diameter of each fine particle is 10 nm or more and 100 ?m or less, and an inner diameter of the tube is 0.01 mm or more and 100 mm or less.

Abstract: [Object] To provide a biodegradable material that has sufficient mechanical strength, considering in vivo use also, and that can suppress pH changes caused by acidic degradation products. [Solving Means] Provided is a biodegradable material using polyester as a base material, including calcium phosphate particles having an average particle diameter of 10 to 1000 nm.

Abstract: Silver particles are prepared by aggregating silver ions in accordance with a method including steps of (a), in preparing a mixed solution by adding a thiol compound to a solution containing silver ions, adjusting an amount of the thiol compound added to the solution and (b) adding a reducing agent to the mixed solution. This allows a particle size and antibacterial activity of the silver particles to be easily adjusted.

Abstract: Provided is a functional nonwoven fabric that has good feeling upon use, such as hand feeling (softness) or texture, and is capable of stably exhibiting the characteristics of hydroxyapatite (for example, microbe adsorption property). Disclosed is a functional nonwoven fabric in which sintered hydroxyapatite particles are fixed by thermal fusion bonding to a surface of a nonwoven fabric containing fibers, at least surfaces of the fibers being mainly composed of a thermoplastic resin, wherein a shearing rigidity of the functional nonwoven fabric is 8.5 gf/cm/degree or less.

Abstract: To provide a method for producing a porous calcium phosphate body having open micropores. A porous calcium phosphate body having open and uniform micropores can be produced by the method for producing the porous calcium phosphate body, in which calcium phosphate is subjected to electrospinning.