Patents by Inventor Karl Lederis

Karl Lederis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antihypertensive polypeptides
    Patent number: 4385050
    Abstract: Peptides of the structureR.sub.1 --Ala--Arg--Ile--Glu--Asn--Glu--Glu--Glu--Gln--Ala--Gly--Leu--Asn--Arg--Ly s--Tyr--Leu--Val--R.sub.2whereinR.sub.1 is hydrogen, a peptide residue containing from 1 to 18 amino acid residues, or N-acyl, andR.sub.2 is hydrogen, an alcohol moiety of an ester, an amide, or a peptide residue containing from 1 to 10 amino acid residues,whereinthe acyl group is lower alkanoyl having from 1 to 8 carbon atoms, aroyl, or heterocarbonyl, and the alcohol moiety of the ester is an alkyl group having from 1 to 8 carbon atoms have antihypertensive activity.
    Type: Grant
    Filed: June 26, 1981
    Date of Patent: May 24, 1983
    Assignee: Armour Pharmaceutical Company
    Inventors: Karl Lederis, David Stevenson, Donald B. Olsen, Charles D. Bossinger, Everett Flanigan