Patents by Inventor Karl M. Schumacher

Karl M. Schumacher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DIFFERENTIATING EMBRYONIC STEM CELLS INTO CELLS EXPRESSING AQP-1
    Publication number: 20130268060
    Abstract: The present invention relates to methods of differentiating a human embryonic stem (ES) cell into a cell, specifically a renal epithelial cell, expressing AQP-I. The methods disclosed comprise culturing human ES cells in a renal specific medium in the presence of an extracellular matrix molecule. The cells produced according to said method can be used to treat renal related disorders such as renal failure, nephrosis, Bright's disease and glomerulitis.
    Type: Application
    Filed: June 13, 2013
    Publication date: October 10, 2013
    Inventors: Karl M. Schumacher, Jackie Y. Ying, Annegret Schumacher, Karthikeyan Narayanan, Gunter Maubach
  • Method for differentiating embryonic stem cells into cells expressing AQP-1
    Patent number: 8481316
    Abstract: The present invention relates to methods of differentiating a human embryonic stem (ES) cell into a cell, specifically a renal epithelial cell, expressing AQP-I. The methods disclosed comprise culturing human ES cells in a renal specific medium in the presence of an extracellular matrix molecule. The cells produced according to said method can be used to treat renal related disorders such as renal failure, nephrosis, Bright's disease and glomerulitis.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: July 9, 2013
    Assignee: Agency for Science, Technology and Research
    Inventors: Karl M. Schumacher, Jackie Y. Ying, Annegret Schumacher, Karthikeyan Narayanan, Gunter Maubach
  • Method for extracellular matrix mediated differentiation and proliferation of stem cells
    Patent number: 8372643
    Abstract: There is provided a method of culturing a stem cell on extracellular matrix extracted from support cells and in a stem cell culture medium comprising medium conditioned by the support cells.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: February 12, 2013
    Assignee: Agency for Science, Technology and Research
    Inventors: Jackie Y. Ying, Andrew Chwee Aun Wan, Karthikeyan Narayanan, Karl M. Schumacher
  • METHOD FOR DIFFERENTIATING EMBRYONIC STEM CELLS INTO CELLS EXPRESSING AQP-1
    Publication number: 20110070280
    Abstract: The present invention relates to methods of differentiating a human embryonic stem (ES) cell into a cell, specifically a renal epithelial cell, expressing AQP-I. The methods disclosed comprise culturing human ES cells in a renal specific medium in the presence of an extracellular matrix molecule. The cells produced according to said method can be used to treat renal related disorders such as renal failure, nephrosis, Bright's disease and glomerulitis.
    Type: Application
    Filed: July 21, 2008
    Publication date: March 24, 2011
    Inventors: Karl M. Schumacher, Jackie Y. Ying, Annegret Schumacher, Karthikeyan Narayanan, Gunter Maubach
  • METHOD FOR EXTRACELLULAR MATRIX MEDIATED DIFFERENTIATION AND PROLIFERATION OF STEM CELLS
    Publication number: 20100285585
    Abstract: There is provided a method of culturing a stem cell on extracellular matrix extracted from support cells and in a stem cell culture medium comprising medium conditioned by the support cells
    Type: Application
    Filed: December 5, 2008
    Publication date: November 11, 2010
    Inventors: Jackie Y. Ying, Andrew Chwee Aun Wan, Karthikeyan Narayanan, Karl M. Schumacher
  • CELL-ADHESIVE POLYELECTROLYTE MATERIAL FOR USE AS MEMBRANE AND COATING
    Publication number: 20100111917
    Abstract: A multilayer polyelectrolyte support material is provided that includes a polyelectrolyte layer and a polyelectrolyte-polyethylene glycol layer adjacent to the polyelectrolyte layer. The support material also includes a ligand conjugated to the polyelectrolyte-polyethylene glycol layer, allowing for attachment of a protein or a cell to the support material with controlled orientation.
    Type: Application
    Filed: October 17, 2006
    Publication date: May 6, 2010
    Inventors: Jackie Y. Ying, Andrew C.A. Wan, Karl M. Schumacher