Abstract: Methods of assaying a breath sample from a subject for the presence of one or more toxins or toxin associated compounds are provided. In some embodiments, the one or more toxins or toxin associated compounds includes trichloroethylene (TCE) and/or one or more metabolites thereof. Embodiments of the methods further include providing a toxin exposure assessment that can be used to determine if the subject has been exposed to a toxin and to monitor changes in toxin exposure over time in the subject. In certain embodiments, a machine learning model may be used to determine if a subject has been exposed to one or more toxins.

Abstract: A system comprises a mouth piece to receive exhaled air; a breath chamber to receive exhaled air; a valve to direct exhaled air along a desired flow path, direct purge gas along a desired flow path, control the rate of flow of purge gas, control the rate of flow of exhaled air, block the flow of purge gas, and/or block the flow of exhaled air; a source of purge gas; a CO2 cartridge to remove CO2; a water cartridge to remove water; a breath cartridge to capture VOCs from exhaled air; a temperature control system to control the temperature of CO2 cartridge, a water cartridge, and/or a breath cartridge; a cryostat to contain and limit heat flow to a cryogenic liquid; a flow meter designed to measure the flow of exhaled air and/or purge gas; and a pressure transducer to measure a pressure, a flow rate, and/or a flow volume.

Abstract: A system comprises a mouth piece to receive exhaled air; a breath chamber to receive exhaled air; a valve to direct exhaled air along a desired flow path, direct purge gas along a desired flow path, control the rate of flow of purge gas, control the rate of flow of exhaled air, block the flow of purge gas, and/or block the flow of exhaled air; a source of purge gas; a CO2 cartridge to remove CO2; a water cartridge to remove water; a breath cartridge to capture VOCs from exhaled air; a temperature control system to control the temperature of CO2 cartridge, a water cartridge, and/or a breath cartridge; a cryostat to contain and limit heat flow to a cryogenic liquid; a flow meter designed to measure the flow of exhaled air and/or purge gas; and a pressure transducer to measure a pressure, a flow rate, and/or a flow volume.

Abstract: The present disclosure provides methods and devices for early diagnosis of an infection, for example by the COVID-19 virus, and determining a course of action for treatment of the infection.

Abstract: A system comprises a mouth piece to receive exhaled air; a breath chamber to receive exhaled air; a valve to direct exhaled air along a desired flow path, direct purge gas along a desired flow path, control the rate of flow of purge gas, control the rate of flow of exhaled air, block the flow of purge gas, and/or block the flow of exhaled air; a source of purge gas; a CO2 cartridge to remove CO2; a water cartridge to remove water; a breath cartridge to capture VOCs from exhaled air; a temperature control system to control the temperature of CO2 cartridge, a water cartridge, and/or a breath cartridge; a cryostat to contain and limit heat flow to a cryogenic liquid; a flow meter designed to measure the flow of exhaled air and/or purge gas; and a pressure transducer to measure a pressure, a flow rate, and/or a flow volume.