Patents by Inventor Karl Mettinger

Karl Mettinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sequential therapy comprising a 20(S)-camptothecian and a pyrimidine base analog
    Publication number: 20060052334
    Abstract: A method is provided for treating a patient having a disease associated with undesirable or uncontrolled cell proliferation, the method comprising: administering to the patient a 20(S)-camptothecin for a period of time during which a pyrimidine base analog is not being administered to the patient; and administering a pyrimidine base analog to the patient.
    Type: Application
    Filed: September 23, 2005
    Publication date: March 9, 2006
    Inventors: Joseph Rubinfeld, Karl Mettinger, John Lyons, Lawrence Romel
  • Methods and compositions for treatment of ovarian cancer
    Patent number: 6334445
    Abstract: Compositions and methods are provided which are effective in treating ovarian cancer. These compositions are easily administered by long term infusion schedules of at least 72 hours, and can be given in dosages that are safe and provide for manageable side effects. These methods and compositions for treating ovarian cancer in patients whose tumors progressed or failed to respond during prior taxane treatment of shorter duration. Surprisingly, it has been shown that longer infusion periods, such as 96 hours, give substantially lower neuropathy and certain other side effects than shorter term infusions.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: January 1, 2002
    Assignee: Baker Norton Pharmaceuticals, Inc.
    Inventor: Karl Mettinger