Abstract: The current disclosure provides methods and composition for treatment of autoimmune and inflammatory conditions, including systemic lupus erythematosus and antiphospholipid syndrome. Certain aspects of the disclosure are directed to methods for treatment of an autoimmune or inflammatory condition comprising administering a composition comprising a therapeutically effective amount of NAPc2 or NAPc2/proline. Further aspects include pharmaceutical compositions comprising NAPc2 or NAPc2/proline and, in some cases, one or more additional anti-inflammatory agents.

Abstract: A foot brake valve (2?) of a pneumatic brake system in a motor vehicle has an installation plate (4?), on which a brake pedal (14) is pivotably mounted and to which a housing (18?) of a control unit (16, 26) is fastened. A spring-loaded plunger piston (36) in actuating contact with the brake pedal (14) is guided axially movably in an annular collar (50) projecting upward out of the installation plate (4?). For fastening the housing (18?) of the control unit (16, 26) to the installation plate (4?), the housing (18?) has an intermediate flange (48) which is screw-connected to the main part of the housing (18?) and has the annular collar (50). The intermediate flange (48) is coaxially rotatably about a vertical central axis (32), and is connectable in non-positively locking fashion to the installation plate (4?) via a releasable clamping connection (62).

Abstract: The disclosure relates to a method for radially aligning wheelsets of rail vehicles relative to a coordinate system of a wheelset diagnosis tool and/or wheelset machine tool, which method can be implemented quickly with sufficient precision and comprises the following steps: a) positioning the wheelset at a working position of the tool; b) defining a tool-side coordinate system in an assumed wheel centre point of each wheel, where an X-axis adopts a vertical extent, a Y-axis adopts a horizontal extent and a Z-axis describes the resulting depth extent of the wheel; c) measuring the distance of the wheel backs with respect to one another and defining the Z-position=0 on each wheel back; d) defining a unique Z-position for each measuring point; e) positioning each measuring sensor at the specified Z-position; f) measuring the X-position of each measuring point; g) aligning the wheelset by vertically displacing one of the wheels in order to match the X-positions of the measuring points of two wheels.

Abstract: The invention relates to an energy supply circuit of electric components, in particular for a motor vehicle, having an accumulator, wherein a discharge monitoring circuit monitors the energy stored in the accumulator. If the energy stored in the accumulator falls below a threshold value, the discharge monitoring circuit switches off the energy supply at least of individual components, in particular of all components.

Abstract: The present invention relates to a method for solid-state synthesis of ceramic materials, in particular of oxide materials or cuprates, comprising or consisting of the step of providing starting material in amounts effective to produce the ceramic material and, thereafter, applying a treatment to said material by use of a solid-state reaction therein, said reaction being performed by irradiating said material from at least one light source with ultraviolet light. The present invention also relates to methods for producing thin films and to a use of the method for production of high-temperature superconductors.

Abstract: A double roller cage for a double-row cylinder roller bearing, with a central ring part (1) from which webs (2, 3) protrude axially on both sides, wherein the webs (2; 3) of one side in each case form a row of bearings (4; 5) together with the rolling bodies arranged therein, wherein every two adjacent webs (2; 3) of a row of bearings (4; 5) delimit a receiving pocket (6; 7) for a rolling body, and in which, at least in one row of bearings (5), the webs (3) are designed so as to taper in the circumferential direction for a radial filling of the receiving pockets (7) with the rolling bearings. So that the double roller cage has satisfactory running behavior and is relatively simple and cost-effective to produce, recesses (12, 12?, 13, 14, 16) are formed on the other of the two rows of bearings (4; 5) in order to produce a symmetrical mass distribution between the two rows of bearings (4; 5).

Abstract: A reel changer of a printing press has a securing assembly for a safety area. The safety area extends on a receiving end or on a dispensing side of the reel changer at least over the entire width to the end-face side frames. These side frames comprise vertically supported frame parts and optionally also include switch boxes end or side boxes that are arranged directly on the side frames. The safety area is substantially completely enclosed by the reel changer and by one or more connected units and or mechanical blocking devices and by one or more sensor-monitored access assemblies in such a way that operators can enter during operation only by the use of the one or more monitored access assemblies. A control element for controlling functions of the reel changer is physically separate from the reel changer and is arranged at a distance from the side frames at a location that can be reached by an operator positioned outside the safety area.

Abstract: The invention relates to an energy supply circuit of electric components, in particular for a motor vehicle, having an accumulator, wherein a discharge monitoring circuit monitors the energy stored in the accumulator. If the energy stored in the accumulator falls below a threshold value, the discharge monitoring circuit switches off the energy supply at least of individual components, in particular of all components.

Abstract: An anti-friction bearing, including a bearing ring (2), a bearing cage (5) for receiving at least one rolling body (4), a power supply unit (8) which is configured as a claw pole generator, wherein the claw pole generator (8) includes a first claw ring (10) with a sequence of first claws (11) and a second claw ring (12) which is offset in the circumferential direction of the bearing ring (2) and has a sequence of second claws, wherein the two claw rings (10, 12) surround an induction coil (9) encircling in the circumferential direction of the bearing ring (2), wherein the claws (11) of the two claw rings (10, 12) form, with a sequence of magnetic poles (14) encircling in the circumferential direction, magnetic circuits which surround the induction coil (9).

Abstract: A bearing, in particular rolling contact bearing (1), having a first bearing ring (2), a second bearing ring (3) and an energy production unit (8) designed as a claw pole generator, wherein the claw pole generator (8) includes a first claw ring (10) with a sequence of first claws (11) and a second claw ring (12) which is offset in the revolving direction of the axis of rotation (6) and has a sequence of second claws, wherein the two claw rings (10, 12) surround an induction coil (9) encircling the axis of rotation (6), wherein the claws (11) of the two claw rings (10, 12) together with a sequence of magnetic poles (14) encircling the axis of rotation (6) form magnetic circuits surrounding the induction coil (9).

Abstract: A low computation method for operating auto ignition combustion engines, in which outputs, in particular a requested torque set point TQI_SP is directly linked to an injected fuel mass flow distribution, to the EGR rate and the air control by taking into account engine out emissions & drivability constrains by using a multi-objective optimization method. A method to monitor in the embedded controller the indicated torque, TQI is also proposed.

Abstract: A double roller cage for a double-row cylinder roller bearing, with a central ring part (1) from which webs (2, 3) protrude axially on both sides, wherein the webs (2; 3) of one side in each case form a row of bearings (4; 5) together with the rolling bodies arranged therein, wherein every two adjacent webs (2; 3) of a row of bearings (4; 5) delimit a receiving pocket (6; 7) for a rolling body, and in which, at least in one row of bearings (5), the webs (3) are designed so as to taper in the circumferential direction for a radial filling of the receiving pockets (7) with the rolling bearings. So that the double roller cage has satisfactory running behavior and is relatively simple and cost-effective to produce, recesses (12, 12?, 13, 14, 16) are formed on the other of the two rows of bearings (4; 5) in order to produce a symmetrical mass distribution between the two rows of bearings (4; 5).

Abstract: A reel changer of a printing press has a securing assembly for a safety area. The safety area extends on a receiving end or on a dispensing side of the reel changer at least over the entire width to the end-face side frames. These side frames comprise vertically supported frame parts and optionally also include switch boxes end or side boxes that are arranged directly on the side frames. The safety area is substantially completely enclosed by the reel changer and by one or more connected units and or mechanical blocking devices and by one or more sensor-monitored access assemblies in such a way that operators can enter during operation only by the use of the one or more monitored access assemblies. A control element for controlling functions of the reel changer is physically separate from the reel changer and is arranged at a distance from the side frames at a location that can be reached by an operator positioned outside the safety area.

Abstract: A hazardous area in the region surrounding a reel transport of a reel changer is secured. A contactless protective device is located at the access boundaries of the region. This protective device can be deactivated for feeding and/or removing a known object and comprises an evaluation unit. The protective device is configured as a light curtain that is comprised of a plurality of light beams that run in parallel to each other. The evaluation unit includes an assembly for detecting the sequence of the interruption of the light beams during the feeding and/or the removal of an object. Based on the detected sequence of interruption of the light beams, a known object, that is permitted to access the hazardous area, is detected. The protective device is deactivated in this situation. Securing the hazardous area further includes the provision of a second contactless protective device that is permanently active.

Abstract: A hazardous area in the region surrounding a reel transport of a reel changer is secured. A contactless protective device is located at the access boundaries of the region. This protective device can be deactivated for feeding and/or removing a known object and comprises an evaluation unit. The protective device is configured as a light curtain that is comprised of a plurality of light beams that run in parallel to each other. The evaluation unit includes an assembly for detecting the sequence of the interruption of the light beams during the feeding and/or the removal of an object. Based on the detected sequence of interruption of the light beams, a known object, that is permitted to access the hazardous area, is detected. The protective device is deactivated in this situation. Securing the hazardous area further includes the provision of a second contactless protective device that is permanently active.

Abstract: A low computation method for operating auto ignition combustion engines, in which outputs, in particular a requested torque set point TQI_SP is directly linked to an injected fuel mass flow distribution, to the EGR rate and the air control by taking into account engine out emissions & drivability constrains by using a multi-objective optimization method. A method to monitor in the embedded controller the indicated torque, TQI is also proposed.

Abstract: The invention proposes a fitness and therapy mat for standing and walking made of foamed material for sport, gymnastic, and therapeutic purposes. The foamed material used has an open cell structure. Thus the elasticity of the foamed material structure alone determines the spring action of the mat when the mat is under stress. The spring action of the fitness and therapy mat approaches the ideal spring, and the resilience shows minimal damping.

Abstract: The present invention relates to functional footwear of a new concept, which adapts itself to the shape of a foot and gives a soft feeling when walking. The footwear includes: an upper foot fixing section (1) for covering and fixing an upper portion of a foot; and a foot supporting section attached to the upper foot fixing section for supporting a lower portion of the foot. The foot supporting section includes a resilient mat (2) having a soft elastic body, which can be deformed according to the shape of the foot. The footwear has a simple structure and can give a feeling of walking barefoot on a sponge mat or on a lawn like a soft carpet to provide complete comfort to the wearer during walking.