Patents by Inventor Karl N. Johansson

Karl N. Johansson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4798833
    Abstract: Antivirally active compounds of the formula ##STR1## wherein A is ##STR2## wherein m is 1 or 2,n is 1 or 2, whereby m is 1 when n is 2 and m is 2 when n is 1,R.sub.a ' is (CH.sub.2).sub.p OH, NHCONH.sub.2 or COR.sub.a ",R.sub.a " is hydrogen, hydroxy or amino,p is 1 to 4,R.sub.b ' and R.sub.b " are independently selected from hydrogen or (CH.sub.2).sub.p OH,with the proviso that at least one of R.sub.b ' or R.sub.b " is hydrogen; orR.sub.b ' and R.sub.b " together constitute an additional carbon-carbon bond to form an alkyne; or a physiologically acceptable salt, geometric or optical isomer thereof; pharmaceutical preparations containing the compounds and methods for treatment of virus infections.
    Type: Grant
    Filed: February 6, 1987
    Date of Patent: January 17, 1989
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Karl N. Johansson, Bjorn G. Lindborg, Jan-Olof Noren
  • Patent number: 4591583
    Abstract: A pharmaceutical preparation containing as active ingredient a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different, and each is selected from the group consisting of hydrogen, alkyl groups containing 1-6 carbon atoms; cycloalkyl groups containing 3-6 carbon atoms; cycloalkyl-alkyl groups containing 4-6 carbon atoms; 1-adamantyl; 2-adamantyl, benzyl; and phenyl groups of the formula ##STR2## wherein R.sub.4 and R.sub.5 are the same or different and each is selected from the group consisting of hydrogen, halogen, alkyl having 1, 2, or 3 carbon atoms, alkoxy having 1, 2, or 3 carbon atoms, alkoxycarbonyl having 2-7 carbon atoms and alkylcarbonyl groups having 2-7 carbon atoms; or R.sub.4 and R.sub.5 together form a straight saturated alkylene chain having 3 or 4 carbon atoms and being bound to adjacent positions, i.e. 2,3- or 3,4- in the phenyl ring; and R.sub.
    Type: Grant
    Filed: December 17, 1982
    Date of Patent: May 27, 1986
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Ake J. E. Helgstrand, Karl N. Johansson, Alfons Misiorny, Jan O. Noren, Goran B. Stening
  • Patent number: 4495190
    Abstract: Novel antiviral compounds of the formula ##STR1## wherein each of R.sub.1 and R.sub.2, which are the same or different is hydrogen, hydroxy or fluoro; provided that R.sub.1 or R.sub.2 is hydrogen when R.sub.1 and R.sub.2 are different, and provided that R.sub.1 and R.sub.2 are hydroxy or fluoro when R.sub.1 and R.sub.2 are the same; or a physiologically acceptable salt or an optical isomer thereof, methods for their preparation, pharmaceutical preparations containing the compounds, and methods for the treatment of virus infections and other diseases caused by viruses.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: January 22, 1985
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Curt-Erik Hagberg, Karl N. Johansson, Zsuzsanna M. I. Kovacs, Goran B. Stening
  • Patent number: 4386081
    Abstract: A pharmaceutical preparation containing as active ingredient a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different, and each is selected from the group consisting of hydrogen, alkyl groups containing 1-6 carbon atoms; cycloalkyl groups containing 3-6 carbon atoms; cycloalkyl-alkyl groups containing 4-6 carbon atoms; 1-adamantyl; 2-adamantyl, benzyl; and phenyl groups of the formula ##STR2## wherein R.sub.4 and R.sub.5 are the same or different and each is selected from the group consisting of hydrogen, halogen, alkyl having 1, 2, or 3 carbon atoms, alkoxy having 1, 2, or 3 carbon atoms, alkoxycarbonyl having 2-7 carbon atoms and alkylcarbonyl groups having 2-7 carbon atoms; or R.sub.4 and R.sub.5 together form a straight saturated alkylene chain having 3 or 4 carbon atoms and being bound to adjacent positions, i.e. 2,3- or 3,4- in the phenyl ring;and R.sub.
    Type: Grant
    Filed: November 13, 1979
    Date of Patent: May 31, 1983
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Ake J. E. Helgstrand, Karl N. Johansson, Alfons Misiorny, Jan O. Noren, Goran B. Stening