Patents by Inventor Karl Philipp

Karl Philipp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12369812
    Abstract: Cardiac MR data sets are acquired over cardiac cycles and based on a trigger event, with each cardiac MR data set having a corresponding time stamp. A series of time differences is determined between acquisitions of the cardiac MR data sets based on the time stamps, and a default time difference representing the time difference between two consecutive cardiac MR data sets is determined, which were acquired using correct trigger events. A pair of incorrect time differences is determined, each incorrect time difference representing a time difference between two consecutive MR data sets in which at least one MR data set was acquired using an incorrect trigger event. Approved MR data sets are determined comprising cardiac MR data sets from the cardiac MR data sets which were acquired using the correct trigger event, based on the pair of incorrect time differences, and the approved MR data sets are further processed.
    Type: Grant
    Filed: August 10, 2023
    Date of Patent: July 29, 2025
    Assignee: Siemens Healthineers AG
    Inventors: Karl-Philipp Kunze, Radhouene Neji
  • Publication number: 20250231264
    Abstract: A computer-implemented method for determining a T1? map, using a magnetic resonance device, wherein magnetic resonance data are acquired from multiple slices of an imaging volume of a patient for different spin lock times provided by a T1? preparation module, which comprises at least one spin lock pulse, and the T1? map is reconstructed from the magnetic resonance data of the different spin lock times, wherein the magnetic resonance data of each slice are acquired during a same breath hold interval, the method including: using a slice selective T1? preparation module as the slice selective T1? preparation module, and acquiring magnetic resonance data of at least two slices in at least one of the breath hold intervals.
    Type: Application
    Filed: January 17, 2025
    Publication date: July 17, 2025
    Applicants: Siemens Healthineers AG, King's College London
    Inventors: Sebastien Roujol, Andrew Tyler, Karl-Philipp Kunze
  • Patent number: 12352838
    Abstract: A Computer-implemented method of reconstructing a dynamic series of motion-compensated magnetic resonance images of a patient is provided. Images of a patient are acquired over time, at least partially in free-breathing, at a first image resolution and on a frame-by-frame basis. Each frame of the k-space data includes a first subset of data points having a first sample density and a second subset of data points having a second sample density. For each frame, a sub-group of the first subset and the second subset of the k-space data is selected, and an image is reconstructed at a second image resolution. The motion between the second image resolution images is estimated in the form of motion fields. The motion information is incorporated into a final reconstruction of a dynamic series of motion-compensated magnetic resonance images of the patient at a third image resolution.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: July 8, 2025
    Assignee: Siemens Healthineers AG
    Inventors: Karl-Philipp Kunze, Radhouene Neji
  • Publication number: 20240219498
    Abstract: Techniques for performing magnetic resonance imaging are provided, which include applying at least two different pulse sequences designed for simultaneous excitation of at least two slices, and measuring k-space lines of the slices with a Parallel Imaging Results in Higher Acceleration (CAIPIRINHA) sampling scheme. Each pulse sequence comprises multiple different phase patterns, each phase pattern is used for exciting one of the slices, and the phase patterns of different pulse sequences are arranged relative to each other according to a Hadamard encoding. Images are reconstructed from the measured k-space lines by forming image slices based on different linear combinations of corresponding slices acquired with different pulse sequences.
    Type: Application
    Filed: November 28, 2023
    Publication date: July 4, 2024
    Applicant: Siemens Healthcare GmbH
    Inventors: Daniel Staeb, Karl-Philipp Kunze, Peter Speier
  • Publication number: 20240049976
    Abstract: Cardiac MR data sets are acquired over cardiac cycles and based on a trigger event, with each cardiac MR data set having a corresponding time stamp. A series of time differences is determined between acquisitions of the cardiac MR data sets based on the time stamps, and a default time difference representing the time difference between two consecutive cardiac MR data sets is determined, which were acquired using correct trigger events. A pair of incorrect time differences is determined, each incorrect time difference representing a time difference between two consecutive MR data sets in which at least one MR data set was acquired using an incorrect trigger event. Approved MR data sets are determined comprising cardiac MR data sets from the cardiac MR data sets which were acquired using the correct trigger event, based on the pair of incorrect time differences, and the approved MR data sets are further processed.
    Type: Application
    Filed: August 10, 2023
    Publication date: February 15, 2024
    Applicant: Siemens Healthcare GmbH
    Inventors: Karl-Philipp Kunze, Radhouene Neji
  • Publication number: 20230401767
    Abstract: One or more example embodiments of the present invention relates to a method for generating MR images of the heart, the method comprising acquiring and reconstructing a first set of 2D reference images of the heart during a reference heartbeat, the first set comprising a first reference image acquired along a first reference plane position thorough the heart and acquiring a second set of 2D images of the heart during a second heartbeat.
    Type: Application
    Filed: June 6, 2023
    Publication date: December 14, 2023
    Applicant: Siemens Healthcare GmbH
    Inventors: Karl-Philipp KUNZE, Radhouene NEJI
  • Publication number: 20230400544
    Abstract: One or more example embodiments discloses a computer-implemented method of reconstructing a dynamic series of magnetic resonance images of a patient, comprising acquiring first and second k-space data of the patient; reconstructing at least one proton density weighted image based on the first k-space data; generating a dynamic series of processing images based on the second k-space data and temporal regularization; applying a motion correction to processing image based on an estimated motion; registering the proton density weighted image to the motion corrected image; and applying a signal intensity correction to the dynamic series of motion corrected images based on the proton density weighted image.
    Type: Application
    Filed: June 6, 2023
    Publication date: December 14, 2023
    Applicant: Siemens Healthcare GMBH
    Inventors: Karl-Philipp KUNZE, Radhouene NEJI
  • Patent number: 11782115
    Abstract: A computer-implemented method of reconstructing a motion-compensated magnetic resonance image uses raw k-space data acquired at a first resolution over successive respiratory and/or cardiac cycles of a patient. After binning data based on corresponding motion states derived from these cycles, the resolution of the binned K-space data in each bin is reduced. This is done by selecting a sub-group of binned k-space data. Bin images are reconstructed from the reduced-resolution data, and histogram-equalised versions of the reconstructed reduced-resolution bin image generated for each bin. Motion fields are estimated and interpolated to the first resolution such that motion data can be incorporated into a final reconstruction of a motion compensated image.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: October 10, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Karl-Philipp Kunze, Radhouene Neji
  • Publication number: 20230047835
    Abstract: A method for producing a nano-porous membrane with one or up to four graphene layers, pores in the membrane having an average pore size in the range of 0.2-50 or 0.3-10 nm, wherein the method involves the following steps: a) generation of a contiguous, essentially non-porous membrane with one or up to four graphene layers; b) distributed point wise defect creation in the non-porous membrane with one or up to four graphene layers by way of irradiation; c) generation and successive growth of the pores at the defects generated in step b) by thermal annealing in the gas phase, e.g. under 02 at a temperature in the range of 250° C. to less than 400° C.
    Type: Application
    Filed: November 17, 2020
    Publication date: February 16, 2023
    Applicant: ETH Zurich
    Inventor: Karl-Philipp SCHLICHTING
  • Publication number: 20230010419
    Abstract: A Computer-implemented method of reconstructing a dynamic series of motion-compensated magnetic resonance images of a patient is provided. Images of a patient are acquired over time, at least partially in free-breathing, at a first image resolution and on a frame-by-frame basis. Each frame of the k-space data includes a first subset of data points having a first sample density and a second subset of data points having a second sample density. For each frame, a sub-group of the first subset and the second subset of the k-space data is selected, and an image is reconstructed at a second image resolution. The motion between the second image resolution images is estimated in the form of motion fields. The motion information is incorporated into a final reconstruction of a dynamic series of motion-compensated magnetic resonance images of the patient at a third image resolution.
    Type: Application
    Filed: June 29, 2022
    Publication date: January 12, 2023
    Inventors: Karl-Philipp Kunze, Radhouene Neji
  • Patent number: 11517198
    Abstract: The present techniques relate to a techniques for performing cardiac perfusion imaging in order to detect perfusion defects in the myocardium. The present techniques relate to methods for performing cardiac perfusion imaging by performing at least two image acquisitions using different, customizable saturation delay times, which improves the ability to detect defects.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: December 6, 2022
    Assignees: Siemens Healthcare Limited, King's College London
    Inventors: Giulio Ferrazzi, Amedeo Chiribiri, Karl-Philipp Kunze, Sarah McElroy, Radhouene Neji, Sebastien Roujol
  • Publication number: 20220349976
    Abstract: A computer-implemented method of reconstructing a motion-compensated magnetic resonance image uses raw k-space data acquired at a first resolution over successive respiratory and/or cardiac cycles of a patient. After binning data based on corresponding motion states derived from these cycles, the resolution of the binned K-space data in each bin is reduced. This is done by selecting a sub-group of binned k-space data. Bin images are reconstructed from the reduced-resolution data, and histogram-equalised versions of the reconstructed reduced-resolution bin image generated for each bin. Motion fields are estimated and interpolated to the first resolution such that motion data can be incorporated into a final reconstruction of a motion compensated image.
    Type: Application
    Filed: April 26, 2022
    Publication date: November 3, 2022
    Applicant: Siemens Healthcare GmbH
    Inventors: Karl-Philipp KUNZE, Radhouene NEJI
  • Publication number: 20220336085
    Abstract: A method for reconstructing a set of one or more MRI images from one or more segmented acquisitions of MRI raw data includes, for each respective shot capturing a part of the MRI raw data of the respective images, capturing and reconstructing a low-resolution navigation image of a region of interest, either from the part of the MRI raw data or from an additional MRI raw data acquired adjacent to the part of the MRI raw data in time. Each segmented acquisition consists of a number of shots.
    Type: Application
    Filed: April 15, 2022
    Publication date: October 20, 2022
    Inventors: Karl-Philipp Kunze, Radhouene Neji
  • Patent number: 11253154
    Abstract: A method and system for imaging a body using a magnetic resonance imaging (MRI) apparatus, including motion tracking of a target object of the body using MRI by generating an MRI image of a region of interest of the body by performing a weighted combination of a signal received by each coil of an MRI apparatus during an MRI scan.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: February 22, 2022
    Assignees: Siemens Healthcare GmbH, King's College, London
    Inventors: Christoph Forman, Radhouene Neji, Karl-Philipp Kunze, Rene Botnar, Claudia Prieto
  • Publication number: 20220003653
    Abstract: An automatic analyzer for analyzing a medical probe includes an analysis cell for the probe, a piezo element, and an analysis device. The piezo element can be operated by applying a voltage and a frequency, and in the process an acoustic wave field is generated. A probe located in the analysis cell is located in the acoustic wave field when the piezo element is being operated.
    Type: Application
    Filed: October 15, 2019
    Publication date: January 6, 2022
    Inventors: Lukas Richter, Ann-Kathrin Reichenwallner, Oliver Schmidt, Gabriele Hornig, Manfred Ruhrig (deceased), Karl-Philipp Matheis, Matthias Ugele
  • Publication number: 20210228080
    Abstract: The present techniques relate to a techniques for performing cardiac perfusion imaging in order to detect perfusion defects in the myocardium. The present techniques relate to methods for performing cardiac perfusion imaging by performing at least two image acquisitions using different, customizable saturation delay times, which improves the ability to detect defects.
    Type: Application
    Filed: January 27, 2021
    Publication date: July 29, 2021
    Applicants: Siemens Healthcare Limited, King's College London
    Inventors: Giulio Ferrazzi, Amedeo Chiribiri, Karl-Philipp Kunze, Sarah McElroy, Radhouene Neji, Sebastien Roujol
  • Publication number: 20210059529
    Abstract: A method and system for imaging a body using a magnetic resonance imaging (MRI) apparatus, including motion tracking of a target object of the body using MRI by generating an MRI image of a region of interest of the body by performing a weighted combination of a signal received by each coil of an MRI apparatus during an MRI scan.
    Type: Application
    Filed: August 26, 2020
    Publication date: March 4, 2021
    Applicants: Siemens Healthcare GmbH, King's College London
    Inventors: Christoph Forman, Radhouene Neji, Karl-Philipp Kunze, Rene Botnar, Claudia Prieto
  • Patent number: 8544831
    Abstract: A clamp is provided, having a slide rail, a fixed arm fastened to the slide rail and on which a first abutment surface for a workpiece is arranged, a sliding arm displaceable on the slide rail, and a housing arrangement, on which are held a first bearing device and a second bearing device, by means of which the housing arrangement is guided on the slide rail. The sliding arm is positioned between the first and second bearing devices. A second abutment surface for a workpiece is arranged on the housing arrangement and faces the first abutment surface. A force application device is held on the sliding arm and acts on a pressure piece held on the housing arrangement. The housing arrangement has a first housing part with a housing interior having an opening. The sliding arm is brought into the housing interior through the opening during production of the clamp.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: October 1, 2013
    Assignee: BESSEY Tool GmbH & Co. KG
    Inventors: Thomas Klein, Hans Roesch, Gerhard Kloepfer, Karl Philipp
  • Patent number: 8313095
    Abstract: A device for a clamping tool for applying pressure to a workpiece is provided, comprising a contacting area for a workpiece, a holding head locating space for a holding head of the clamping tool, and at least one locking element for fixing the holding head in the holding head locating space, which said locking element is arranged in a locking element locating space and must be passed through by the holding head, wherein the at least one locking element and the locking element locating space are formed in such a manner that the amount of force required to pass through the at least one locking element in the direction of insertion of the holding head into the holding head locating space is smaller than the amount of force required to pass therethrough in the direction of extraction of the holding head from the holding head locating space.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: November 20, 2012
    Assignee: BESSEY Tool GmbH & Co. KG
    Inventors: Gerhard Kloepfer, Karl Philipp, Hans Roesch
  • Publication number: 20100187739
    Abstract: A clamp is provided, comprising a slide rail, a fixed arm, which is fastened to the slide rail and on which a first abutment surface for a workpiece is arranged, a sliding arm, which is displaceable on the slide rail, a housing arrangement, on which are held a first bearing device and a second bearing device spaced from the first bearing device, by means of which the housing arrangement is displaceably guided on the slide rail, wherein the sliding arm is positioned between the first bearing device and the second bearing device, wherein there is arranged on the housing arrangement a second abutment surface for a workpiece, the second abutment surface facing the first abutment surface, wherein a force application device is provided, which is held on the sliding arm and which acts on a pressure piece which is held on the housing arrangement, wherein the housing arrangement has a first housing part with a housing interior having an opening, which faces the first abutment surface and by means of which the sliding
    Type: Application
    Filed: January 20, 2010
    Publication date: July 29, 2010
    Applicant: BESSEY Tool GmbH & Co. KG
    Inventors: Thomas Klein, Hans Roesch, Gerhard Kloepfer, Karl Philipp