Patents by Inventor Karl PLÖSSL

Karl PLÖSSL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HBED-bisphosphonates, radiometal conjugates and their use as theranostic agents
    Patent number: 10253052
    Abstract: The present invention relates to compounds according to Formula I or Formula II, which are potential bone imaging agents. Certain compounds labeled with 68Ga displayed excellent bone uptake and retention. The present invention also relates to pharmaceutical compositions comprising a pharmaceutical acceptable carrier and a compound of Formula I or Formula II or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: April 9, 2019
    Assignee: Five Eleven Pharma Inc.
    Inventors: Hank F. Kung, Zehui Wu, Seok Rye Choi, Karl Plössl, Zhihao Zha
  • HBED-Bisphosphonates, Radiometal Conjugates and Their Use as Theranostic Agents
    Publication number: 20170022224
    Abstract: The present invention relates to compounds according to Formula I or Formula II, which are potential bone imaging agents. Certain compounds labeled with 68Ga displayed excellent bone uptake and retention. The present invention also relates to pharmaceutical compositions comprising a pharmaceutical acceptable carrier and a compound of Formula I or Formula II or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 6, 2016
    Publication date: January 26, 2017
    Applicant: Five Eleven Pharma Inc.
    Inventors: Hank F. KUNG, Zehui Wu, Seok Rye Choi, Karl PLÖSSL, Zhihao Zha
  • Dopamine and serotonin transporter ligands and imaging agents
    Patent number: 6241963
    Abstract: This invention presents a series novel tropane-based derivatives complexed with either technetium or rhenium that are specific for central nervous system receptors, in particular, dopamine or serotonin receptors. The compounds of the invention have utility, inter alia, as imaging agents for CNS receptors. Methods of using these novel compounds as imaging agents are presented, as are intermediates and methods for making these novel compounds.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: June 5, 2001
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Hank Kung, Sanath Meegalla, Mei-Ping Kung, Karl Plossl