Patents by Inventor Karl Riabowol

Karl Riabowol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies against the tumor suppressor gene ING1
    Patent number: 6747133
    Abstract: The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related tumor suppressor proteins and peptides.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: June 8, 2004
    Assignee: University Technologies International Inc.
    Inventors: Igor Garkavtsev, Karl Riabowol
  • ING-encoded p33ING1 protein as a mediator of p53 signaling pathway in mammalian cells
    Publication number: 20030073084
    Abstract: The invention relates to a novel tumor suppressor gene, termed ING, genetic suppressor elements derived from this gene, and the protein produced by expression of this gene, known as p33ING1. The invention provides methods for characterizing mammalian cells on the basis of whether such cells express the ING gene, and embodiments of such methods directed at malignant or pre-malignant tissues in an animal for assaying the risk of developing malignant disease by the animal.
    Type: Application
    Filed: October 1, 2001
    Publication date: April 17, 2003
    Applicant: Board of Trustees for University of Illinois
    Inventors: Andrei Gudkov, Igor Garkavstev, Karl Riabowol
  • ING-encoded p33ING1 protein as a mediator of p53 signaling pathway in mammalian cells
    Patent number: 6297366
    Abstract: The invention relates to a novel tumor suppressor gene, termed ING, genetic suppressor elements derived from this gene, and the protein produced by expression of this gene, known as p33ING1. The invention provides methods for characterizing mammalian cells on the basis of whether such cells express the ING gene, and embodiments of such methods directed at malignant or pre-malignant tissues in an animal for assaying the risk of developing malignant disease by the animal.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: October 2, 2001
    Assignee: Board of Trustees of the University of Illinois
    Inventors: Andrei Gudkov, Igor Garkavstev, Karl Riabowol
  • DNA sequence encoding the tumor suppressor gene ING1
    Patent number: 6238918
    Abstract: The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related tumor suppressor proteins and peptides.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: May 29, 2001
    Assignee: University Technologies International, Inc.
    Inventors: Igor Garkavtsev, Karl Riabowol
  • Methods of modulating apoptosis
    Patent number: 6143522
    Abstract: The invention provides novel methods for modulating apoptosis in eukaryotic cells using peptides and proteins derived from p33.sup.ING1 or oligonucleotides derived from the ING1 gene. The invention also provides method of determining the apoptotic characteristic of a eukaryotic cell.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: November 7, 2000
    Assignee: University Technologies International, Inc.
    Inventors: Caren C. Helbing, Karl Riabowol, Randall N. Johnston, Igor Garkavtsev
  • DNA sequence encoding the tumor suppressor gene ING1
    Patent number: 6117633
    Abstract: The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related tumor suppressor proteins and peptides.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: September 12, 2000
    Assignees: University Technologies International Inc., University of Illinois
    Inventors: Igor Garkavtsev, Karl Riabowol, Andrei Gudkov
  • DNA sequence encoding a tumor suppressor gene
    Patent number: 6037121
    Abstract: The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related tumor suppressor proteins and peptides.
    Type: Grant
    Filed: December 8, 1995
    Date of Patent: March 14, 2000
    Assignees: University Technologies International Inc., University of Illinois
    Inventors: Igor Garkavtsev, Karl Riabowol, Andrei Gudkov
  • DNA sequence encoding the tumor suppressor gene ING1
    Patent number: 5986078
    Abstract: The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related tumor suppressor proteins and peptides.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: November 16, 1999
    Assignee: University Technologies International Inc.
    Inventors: Igor Garkavtsev, Karl Riabowol
  • DNA sequence encoding a tumor suppressor gene
    Patent number: 5965398
    Abstract: The invention provides novel tumor suppressor genes, methods for making and using these and related tumor suppressor genes and proteins and peptides, and nucleic acids encoding these and related tumor suppressor proteins and peptides.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: October 12, 1999
    Assignee: University Technologies International Inc.
    Inventors: Igor Garkavtsev, Karl Riabowol