Patents by Inventor Karl Robert Dahnke

Karl Robert Dahnke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5'-SUBSTITUTED NUCLEOSIDE COMPOUNDS
    Publication number: 20160326208
    Abstract: The present invention relates to novel 5?-substituted nucleoside compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer, in particular glioblastomas, melanoma, sarcomas, gastric cancer, pancreatic cancer, cholangiocarcinoma, bladder cancer, breast cancer, non-small cell lung cancer, leukemias including acute myeloid leukemia, and lymphomas.
    Type: Application
    Filed: April 27, 2016
    Publication date: November 10, 2016
    Inventors: Guillermo S CORTEZ, Karl Robert DAHNKE, Michael John GROGAN, Antonio Rodriguez HERGUETA, James Andrew JAMISON, Brian Morgan WATSON, Timothy Andrew WOODS, Zahid Quyoom BONDAY
  • Phenyl-thiophene type vitamin D receptor modulators
    Patent number: 7601850
    Abstract: The present invention relates to novel, non-secosteroidal, phenyl-thiophene compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1?,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: October 13, 2009
    Assignee: Eli Lilly and Company
    Inventors: Karl Robert Dahnke, Robert Peter Gajewski, Charles David Jones, Jared Harris Linebarger, Jianliang Lu, Tianwei Ma, Sunil Nagpal, Todd Parker Simard, Ying Kwong Yee, Emilio Enrique Bunel, Ryan Edward Stites
  • [4-(Benzo[B]thiophen-2-yl) Pyrimidin-2-yl]-amine derivatives as IKK-beta inhibitors for the treatment of cancer and inflammatory diseases
    Patent number: 7547691
    Abstract: The present invention provides compounds of Formula I: useful in the treatment of cancer and inflammatory diseases.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: June 16, 2009
    Assignee: Eli Lilly and Company
    Inventors: Karl Robert Dahnke, Ho-Shen Lin, Michael Enrico Richett, Chuan Shih, Q May Wang, Bo Zhang
  • [4-(Benzo[B]Thiophen-2-Yl) Pyrimidin-2-Yl]-Amine Derivatives As Ikk-Beta Inhibitors For The Treatment Of Cancer And Inflammatory Diseases
    Publication number: 20080306082
    Abstract: The present invention provides compounds of Formula I: useful in the treatment of cancer and inflammatory diseases.
    Type: Application
    Filed: November 15, 2006
    Publication date: December 11, 2008
    Inventors: Karl Robert Dahnke, Ho-Shen Lin, Michael Enrico Richett, Chuan Shih, Q May Wang, Bo Zhang
  • Treatment of mastitis
    Patent number: 6369049
    Abstract: The invention provides new fluorinated cephalosporin antibiotics of Formula I wherein Ra, Rb, Rc, Rd and Re, independently, are H, F or a C1-C6 alkyl-(Z)n— group having at least one fluorine substituent; X is O or S; Y is S, O, or —CH2—; Z is O, S, —SO—, or —SO2—; m and n independently are 0 or 1; and R1 is H, C1-C6-alkyl, phenyl or benzyl, each of which may optionally have up to three substituents selected from halo, C1-C4-alkoxy, phenyl, NO2, C1-C6-alkanoyl, benzoyl, or C1-C6-alkanoyloxy; or a physiologically acceptable salt thereof; and methods of preventing or treating or treating infection, particularly mastitis in ruminants, using these antibiotics.
    Type: Grant
    Filed: April 12, 1999
    Date of Patent: April 9, 2002
    Assignee: Eli Lilly and Company
    Inventor: Karl Robert Dahnke
  • Cephalosporin antibiotics
    Patent number: 6329363
    Abstract: The invention provides new fluorinated cephalosporin antibiotics and methods of preventing or treating infection, particularly mastitis in ruminants, using these antibiotics, and veterinary and pharmaceutical formulations comprising these antibiotics.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: December 11, 2001
    Assignee: Eli Lilly and Company
    Inventor: Karl Robert Dahnke