Patents by Inventor Karl Schenker

Karl Schenker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4600719
    Abstract: Compounds of the class of (2-benzofuranyl)-1,2,3,6-tetrahydropyridines and (2-benzofuranyl)-piperidines which at the ring nitrogen atom are unsubstituted or substituted by a substituent of the class of certain aliphatic, cycloaliphatic and araliphatic radicals, and their pharmaceutically acceptable acid addition salts have valuable pharmacological properties. In particular, they inhibit monoamine oxidase and antagonise the action of tetrabenazine. They are useful as active ingredients for therapeutic compositions for the treatment of mental depression. Specific embodiments are 4-(2-benzofuranyl)-piperidine, 2-(5,6-dimethyl-2-benzofuranyl)-piperidine and their hydrochlorides.
    Type: Grant
    Filed: September 13, 1984
    Date of Patent: July 15, 1986
    Assignee: Ciba Geigy Corporation
    Inventors: Karl Schenker, Raymond Bernasconi
  • Patent number: 4210655
    Abstract: Compounds of the class of (2-benzofuranyl)-1,2,3,6-tetrahydropyridines and (2-benzofuranyl)-piperidines which at the ring nitrogen atom are unsubstituted or substituted by a substituent of the class of certain aliphatic, cycloaliphatic and araliphatic radicals, and their pharmaceutically acceptable acid addition salts have valuable pharmacological properties. In particular, they inhibit monoamine oxidase and antagonize the action of tetrabenazine. They are useful as active ingredients for therapeutic compositions for the treatment of mental depression. Specific embodiments are 4-(2-benzofuranyl)-piperidine, 2-(5,6-dimethyl-2-benzofuranyl)-piperidine and their hydrochlorides.
    Type: Grant
    Filed: April 5, 1978
    Date of Patent: July 1, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Karl Schenker, Raymond Bernasconi
  • Patent number: 4045580
    Abstract: 9-(2-A-3-R-propyl)-9,10-dihydro-9,10-ethano-anthracenes containing the nucleus of the formula ##STR1## wherein R denotes a secondary or tertiary amino group and A denotes a free, etherified or acylated hydroxyl group, their pharmaceutically acceptable salts are useful as psychotropics, especially as anti-depressants.
    Type: Grant
    Filed: February 18, 1976
    Date of Patent: August 30, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Max Wilhelm, Raymond Bernasconi, Angelo Storni, Dieter Beck, Karl Schenker
  • Patent number: 4017542
    Abstract: 9-(2-A-3-R-propyl)-9,10-dihydro-9,10-ethanoanthracenes containing the nucleus of the formula ##STR1## wherein R denotes a secondary or tertiary amino group and A denotes a free, etherified or acylated hydroxyl group, their pharmaceutically acceptable salts are useful as psychotropics, especially as anti-depressants.
    Type: Grant
    Filed: April 2, 1975
    Date of Patent: April 12, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Max Wilhelm, Raymond Bernasconi, Angelo Storni, Dieter Beck, Karl Schenker
  • Patent number: 3968142
    Abstract: Compounds of the formula ##EQU1## in which Ph represents an ortho-phenylene radical which contains in position 4 or 5 an unsubstituted or substituted hydrocarbon radical of aliphatic character, R represents a lower alkyl radical or especially a hydrogen atom, Z represents a free, esterified or amidated carboxyl group, A represents an ethylene radical and X stands for two hydrogen atoms or especially for an oxo group, are useful as chemotherapeutic and prophylactic agents against pain and inflammation.
    Type: Grant
    Filed: October 7, 1969
    Date of Patent: July 6, 1976
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Beck, Karl Schenker, Alberto Rossi