Patents by Inventor Karl Skold

Karl Skold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREPARING BIOLOGICAL SAMPLES FOR ANALYSIS
    Publication number: 20150198510
    Abstract: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
    Type: Application
    Filed: March 25, 2015
    Publication date: July 16, 2015
    Inventors: Karl Skold, Marcus Svensson, Goran Palmers, Per Andren
  • STABILIZATION METHOD FOR BIOLOGICAL SAMPLES BY COMBINATION OF HEATING AND CHEMICAL FIXATION
    Publication number: 20150192502
    Abstract: The present invention provides methods for stabilizing a biological sample for analysis. The invention more particularly provides methods combining heat treatment and chemical fixation of biological samples in order to maintain protein primary structure and post-translational modifications, such as protein phosphorylations.
    Type: Application
    Filed: February 6, 2015
    Publication date: July 9, 2015
    Inventors: Mats Boren, Karl Skold, Marcus Soderquist
  • Preparing biological samples for analysis
    Patent number: 9017964
    Abstract: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
    Type: Grant
    Filed: August 27, 2006
    Date of Patent: April 28, 2015
    Assignee: Denator Aktiebolag
    Inventors: Karl Sköld, Marcus Svensson, Göran Palmers, Per Andrén
  • Stabilization method for biological samples by combination of heating and chemical fixation
    Patent number: 8986947
    Abstract: The present invention provides methods for stabilizing a biological sample for analysis. The invention more particularly provides methods combining heat treatment and chemical fixation of biological samples in order to maintain protein primary structure and post-translational modifications, such as protein phosphorylations.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: March 24, 2015
    Assignee: Denator Aktiebolag
    Inventors: Mats Boren, Karl Skold, Marcus Soderquist
  • METHOD FOR STABILIZATION OF FLUID BIOLOGICAL SAMPLES
    Publication number: 20140154730
    Abstract: The present invention relates to a method for rapid stabilization of fluid biological samples, such as blood samples. More specifically, the method is based on heat stabilization of the fluid biological sample absorbed in a matrix.
    Type: Application
    Filed: July 9, 2012
    Publication date: June 5, 2014
    Applicant: DENATOR AB
    Inventors: Olof Sköld, David Zee-Berg, Karl Sköld, Mats Borén
  • Preparing biological samples for analysis
    Patent number: 8663959
    Abstract: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: March 4, 2014
    Assignee: Denator Aktiebola
    Inventors: Karl Sköld, Marcus Svensson, Göran Palmers, Per Erik Andrén
  • METHOD FOR DETERMINING THE QUALITY OF A BIOLOGICAL SAMPLE
    Publication number: 20090137063
    Abstract: The present invention relates to a method of determining the quality of a biological sample. A method according to the invention may be used to determine if a biological sample is suitable to use in a further biological assay demanding samples of good quality to render an accurate result. The method comprises detecting the presence of protein fragments in the biological sample by using appropriate means. The invention also relates to a kit for determining the quality of a biological sample.
    Type: Application
    Filed: November 28, 2006
    Publication date: May 28, 2009
    Inventors: Karl Skold, Marcus Svensson, Per Andren, Per Svenningsson
  • Preparing Biological Samples for Analysis
    Publication number: 20080268495
    Abstract: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
    Type: Application
    Filed: August 27, 2006
    Publication date: October 30, 2008
    Inventors: Karl Skold, Marcus Svensson, Goran Palmers, Per E. Andren
  • PREPARING BIOLOGICAL SAMPLES FOR ANALYSIS
    Publication number: 20070048792
    Abstract: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
    Type: Application
    Filed: August 28, 2006
    Publication date: March 1, 2007
    Inventors: Karl Skold, Marcus Svensson, Goran Palmers, Per Andren
  • Method and device for preparing a biological sample for biological analyses
    Publication number: 20070048877
    Abstract: The method and devices are for preparing a biological sample for biological analyses. The biological sample has at least one amino acid sequence from an organism. The amino acid sequence is a subject of degradation. The biological sample is physically prepared to enable altering a secondary structure of the amino acid sequence to a deactivated secondary structure, and altering the secondary structure of the amino acid sequence to a deactivated secondary structure by heating the biological sample.
    Type: Application
    Filed: August 26, 2005
    Publication date: March 1, 2007
    Inventors: Karl Skold, Marcus Svensson, Goran Palmers
  • Medical tool
    Patent number: D1019981
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: March 26, 2024
    Assignee: Q-LINEA AB
    Inventors: Anders Lind, Caroline Johansson, Daniel Dolk Djurberg, Henrik Soderstrom, Jan Grawe, Jonas Jarvius, Jonas Melin, Karl Skold, Magnus Sandow, Markus Lindblom, Richard Kroon, Sara Frolander, Sebastian Carlsson, Simon Uhrberg, Ake Strese, Magnus Forslund