Patents by Inventor Karl STAMM

Karl STAMM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL LYSIS ASSAY FOR CELL-FREE DNA ANALYSIS
    Publication number: 20240132957
    Abstract: Provided herein are methods for determining levels of cell lysis in samples, particularly sampled in which amounts of non-self cell-free DNA may be determined.
    Type: Application
    Filed: October 2, 2023
    Publication date: April 25, 2024
    Applicant: Natera, Inc.
    Inventors: Aoy Tomita MITCHELL, Karl STAMM
  • MULTIPLEXED OPTIMIZED MISMATCH AMPLIFICATION (MOMA)-CANCER RISK ASSESSMENT WITH NON-CANCER ASSOCIATED TARGETS
    Publication number: 20210301320
    Abstract: This invention relates to methods and compositions for assessing an amount of non-native nucleic acids in a sample, such as from a subject, and/or noise, background or discordance quality check (QC). The methods and compositions provided herein can be used to determine risk of a condition, such as cancer, in a subject.
    Type: Application
    Filed: November 9, 2020
    Publication date: September 30, 2021
    Applicant: The Medical College of Wisconsin, Inc.
    Inventors: Aoy Tomita Mitchell, Karl Stamm
  • METHODS OF DETERMINING DONOR CELL-FREE DNA WITHOUT DONOR GENOTYPE
    Publication number: 20210032692
    Abstract: This invention relates to methods and systems for assessing an amount of non-subject nucleic acids, such as donor-specific cell-free DNA, in a sample from a subject. The methods and systems can include the simulation of non-subject genotype when unknown. The methods and systems provided herein can be used to determine risk of a condition, such as transplant rejection.
    Type: Application
    Filed: August 17, 2018
    Publication date: February 4, 2021
    Applicant: TAI Diagnostics, Inc.
    Inventors: Aoy Tomita Mitchell, Karl Stamm
  • MULTIPLEXED OPTIMIZED MISMATCH AMPLIFICATION (MOMA)-REAL TIME PCR FOR ASSESSING CANCER
    Publication number: 20200181681
    Abstract: This invention relates to methods and compositions for assessing an amount of cancer-specific nucleic acids in a sample, such as from a subject. The methods and compositions provided herein can be used to determine risk of a condition, such as cancer, in a subject.
    Type: Application
    Filed: April 29, 2017
    Publication date: June 11, 2020
    Applicant: The Medical College of Wisconsin, Inc.
    Inventors: Aoy Tomita Mitchell, Karl Stamm
  • CELL LYSIS ASSAY FOR CELL-FREE DNA ANALYSIS
    Publication number: 20200109449
    Abstract: Provided herein are methods for determining levels of cell lysis in samples, particularly sampled in which amounts of non-self cell-free DNA may be determined.
    Type: Application
    Filed: October 9, 2019
    Publication date: April 9, 2020
    Inventors: Karl Stamm, Aoy Tomita Mitchell
  • METHODS FOR ASSESSING RISK USING TOTAL AND SPECIFIC CELL-FREE DNA
    Publication number: 20190367972
    Abstract: This invention relates to methods and compositions for assessing risk by measuring total and specific cell-free nucleic acids (such as DNA) in a subject. The methods and compositions provided herein can be used to determine risk of a condition, such as transplant rejection.
    Type: Application
    Filed: November 2, 2017
    Publication date: December 5, 2019
    Applicant: The Medical College of Wisconsin, Inc.
    Inventors: Aoy Tomita Mitchell, Michael Mitchell, Karl Stamm
  • METHODS FOR ASSESSING RISK USING MISMATCH AMPLIFICATION AND STATISTICAL METHODS
    Publication number: 20190360033
    Abstract: This invention relates to methods and compositions for assessing an amount of non-native nucleic acids in a sample, such as from a subject. The methods and compositions provided herein can be used to determine risk of a condition, such as transplant rejection, in subject.
    Type: Application
    Filed: November 2, 2017
    Publication date: November 28, 2019
    Applicant: The Medical College of Wisconsin, Inc.
    Inventors: Karl Stamm, Aoy Tomita Mitchell, Michael Mitchell
  • MULTIPLEXED OPTIMIZED MISMATCH AMPLIFICATION (MOMA)-TARGET NUMBER
    Publication number: 20190153521
    Abstract: This invention relates to methods and compositions for assessing an amount of non-native nucleic acids in a sample, such as from a subject. The methods and compositions provided herein can be used to determine risk of a condition in a subject.
    Type: Application
    Filed: April 29, 2017
    Publication date: May 23, 2019
    Applicant: The Medical College of Wisconsin, Inc.
    Inventors: Aoy Tomita Mitchell, Karl Stamm
  • MULTIPLEXED OPTIMIZED MISMATCH AMPLIFICATION (MOMA)-REAL TIME PCR FOR ASSESSING FETAL WELL BEING
    Publication number: 20190153525
    Abstract: This invention relates to methods and compositions for assessing an amount of non-native nucleic acids in a sample, such as from a pregnant subject with the non-native nucleic acids being fetal specific. The methods and compositions provided herein can be used to determine risk of a condition, such as a fetal condition, in a pregnant subject.
    Type: Application
    Filed: April 29, 2017
    Publication date: May 23, 2019
    Applicant: The Medical College of Wisconsin, Inc.
    Inventors: Aoy Tomita Mitchell, Karl Stamm
  • MULTIPLEXED OPTIMIZED MISMATCH AMPLIFICATION (MOMA)-REAL TIME PCR FOR ASSESSING CELL-FREE DNA
    Publication number: 20180142296
    Abstract: This invention relates to methods and compositions for assessing an amount of non-native nucleic acids in a sample, such as from a subject. The methods and compositions provided herein can be used to determine risk of a condition, such as transplant rejection, in subject.
    Type: Application
    Filed: April 29, 2016
    Publication date: May 24, 2018
    Applicant: Medical College of Wisconsin, Inc.
    Inventors: Aoy Tomita MITCHELL, Michael MITCHELL, Karl STAMM