Abstract: The present invention provides anti-angiogenic derived from pigment epithelium-derived factor (PEDF) pharmaceutical compositions comprising the peptides, and methods of preventing angiogenesis. Such methods are useful in treating angiogenesis-associated disorders and diseases.

Abstract: The present invention provides anti-angiogenic derived from pigment epithelium-derived factor (PEDF) pharmaceutical compositions comprising the peptides, and methods of preventing angiogenesis. Such methods are useful in treating angiogenesis-associated disorders and diseases.

Abstract: A calender for surface treatment of material webs, wherein in the event of one sided seizure of an intermediate roller the fixed roller not subject to pressure is adjusted in position at one end such that the asymmetrical linear force profile resulting from the seizure is symmetrically adjusted according to the desired condition in order to optimise processing of the material web.

Abstract: In a calender (1) one or several rollers (2) can be positioned by being raised or lowered jointly with the roller stack disposed therebelow; and vertically displaceable sliding members (3) connected with the roller journals are jointly driven, and are blocked when the roller to be positioned (2) is adjacent the desired working position by way of a separate fixation device (6) supported on the frame (4). In a development of the method the rollers are brought in a desired working position after blocking of the fixation device.

Abstract: An arrangement containing a controlled deflection roll which is supported by means of support or pressure elements against a roll support or beam. There is also provided a regulation arrangement for regulating the position of the roll shell, wherein the position of the roll shell at least at both of its opposed ends is detected by position sensors or feelers and deviations from a set or reference value are processed into two adjustment or positioning magnitudes which act upon the support or pressure elements. Both of the adjustment magnitudes are formed while taking into account a possible difference between both of the reference value-actual value differences and thereafter weighted and grouped together with further adjustment magnitudes and inputted to the support or pressure elements.

Abstract: A controlled deflection roll possesses a roll shell which is radially movable in at least one plane in relation to a roll support. Position feelers or sensors are arranged at the ends of the roll shell. These position feelers control regulators operatively associated with pressure or support elements located between the roll support and the roll shell, as a function of deviations from a predetermined reference or set position, in a manner such that the roll shell is maintained in the reference or set position. It is possible to influence the pressure or support elements by the position feelers either equally or unequally, and specifically, with decreasing intensity in the presence of increasing distance from the related position feeler.