Abstract: A compartmented hard shell capsule for containing active formulations, and methods and apparatuses for forming, filling and encapsulating the compartmented hard shell capsules. The compartmented hard shell capsule includes a cap portion and a body portion. The cap portion has a hollow cavity defining a cap chamber. The body portion can be removably inserted into the cap portion. The body portion has an open end, a closed end and a sidewall defining a hollow cavity and a serrated edge along the open end. The serrated edge may be folded over to form a barrier to enclose the body portion, thereby creating a body chamber that is separate from the cap chamber when the body portion is inserted into the cap portion. The methods for filling and encapsulating the compartmented hard shell capsules can be completed in one continuous process, which increases cost-effectiveness for use of the compartmented hard shell capsules.

Abstract: A method of filling two piece hard shell capsules from top through opening on the center of domes of fused hard shell—FETH capsules, rather than open the “prelock” capsules and filling liquid into the body part of the hard shell capsules. The novel method will (i) significantly reduce the size of air bubbles, (ii) eliminate need for post filling banding or sealing, (iii) able to use any type of two piece hard shell capsules, eliminate the need for specially designed liquid fill friendly capsule and (iv) streamlined the traditional liquid filling process and make it into one continuous process. The capsules filled by the new methods hold 10-15% more liquid and become more competitive to soft gel capsules in terms of costs and efficiency.

Abstract: A dip molding process for the manufacture of allergen free hard capsule shells includes forming an allergen free solution, increasing the temperature of the allergen free solution, filtering the heated allergen free solution, vacuuming the filtrate to remove from 98 percent to 99 percent of air bubbles forming a reduced bubble filtrate, cooling the reduced bubble filtrate, dipping molding pins into the cooled filtrate, withdrawing the molding pins from the cooled filtrate, drying the molding pins with the cooled filtrate to form hard capsule shells, and coating the hard capsule shells with a vegetarian polishing agent. The formed vegan and allergen free hard capsules are dimensionally stable with a combination of (i) mechanical strength, (ii) resistance to cracking and (iii) resiliency. The created vegan and allergen free hard capsules have a body and cap that easily engage while producing an oxygen barrier for product.

Abstract: A film forming solution usable for the manufacture of an allergen free hard capsule containing pullulan polysaccharide, a neutrally charged hydrophilic amide derived from an amino acid, a rheology modifier, a plasticizer, a chelating agent, and Q.S. amount of water. The film forming solution creates hard capsules that are dimensionally stable with a combination of mechanical strength, resistance to cracking and resiliency. The created hard capsules have a body and a cap that easily engage while producing an oxygen barrier for product contained in the allergen free hard capsules.

Abstract: A method for making a clear hard vegetarian gelatin free two piece capsule by creating a first phase network system using a seaweed extract, a galactomannan extract and a rheology modifier. A filler is created for the first phase network by blending a water, a crystalline alcohol, a polysaccharide, and a sugar alcohol at a temperature less than 80 Fahrenheit. The filler is then mixed into the first phase network system forming a biphasic system. Capsules are then formed by dipping conventional moulding pins into the biphasic solution, blowing hot air on the dipped pins in a chamber with a humidity that is no more than 25 percent, blowing away water on the outer surface of the dipped pins to bond and lock moisture to the polysaccharide and removing the capsule pieces from the pins. The two piece capsule has an outer surface which is mechanically and dimensionally stable.

Abstract: A method for making clear hard vegetarian gelatin free two piece capsules by creating the first phase of the biphasic system using seaweed extract, gellan gum, metallic element, maltol extract, seaweed extract and water. A filler is created for the first phase of the biphasic network by blending water, galactomannan extract, and cellulose. The filler is then mixed into the system forming a biphasic system, a first pin is then dripped into the blend and then a second pin is then dripped into the blend. Blowing hot air on the dipped pins, which then blows away water on the outer surface of the dipped pins to bond and lock moisture to the cellulose. A large diameter capsule piece is removed from the first pin and a small diameter capsule piece is removed from the second pin, wherein each capsule piece has an outer surface which is mechanically and dimensionally stable.

Abstract: A method for making a clear hard vegetarian gelatin free two piece capsule by creating a first phase network system using a seaweed extract, a galactomannan extract and a rheology modifier. A filler is created for the first phase network by blending a water, a crystalline alcohol, a polysaccharide, and a sugar alcohol at a temperature less than 80 Fahrenheit. The filler is then mixed into the first phase network system forming a biphasic system. Capsules are then formed by dipping conventional moulding pins into the biphasic solution, blowing hot air on the dipped pins in a chamber with a humidity that is no more than 25 percent, blowing away water on the outer surface of the dipped pins to bond and lock moisture to the polysaccharide and removing the capsule pieces from the pins. The two piece capsule has an outer surface which is mechanically and dimensionally stable.

Abstract: A method for making clear hard vegetarian gelatin free two piece capsules by creating the first phase of the biphasic system using seaweed extract, gellan gum, metallic element, maltol extract, seaweed extract and water. A filler is created for the first phase of the biphasic network by blending water, galactomannan extract, and cellulose. The filler is then mixed into the system forming a biphasic system, a first pin is then dripped into the blend and then a second pin is then dripped into the blend. Blowing hot air on the dipped pins, which then blows away water on the outer surface of the dipped pins to bond and lock moisture to the cellulose. A large diameter capsule piece is removed from the first pin and a small diameter capsule piece is removed from the second pin, wherein each capsule piece has an outer surface which is mechanically and dimensionally stable.

Abstract: A clear soft vegetarian dosage capsule comprising a first and second biphasic film. The first biphasic film has a plurality of first reservoirs and further comprises a polysaccharide, a seaweed extract, a rheology modifier, a buffer and a plasticizer. The second biphasic film has a plurality of second reservoirs having a formulation identical to the first film to ensure a sealing engagement. A dosage amount is disposed in each of the plurality of the reservoirs forming a plurality of filled reservoirs. The dosage amount is an emulsion, oil, hydrophilic liquid. The first film is extruded or overlaid with the second film allowing each of the plurality of second reservoirs to overlay the filled reservoirs and sealed with pressure and a fusion temperature slightly less than the melting point of the first and second films forming clear soft vegetarian dosage capsules that are blown dry, bonding moisture to the polysaccharide.

Abstract: A hard shell capsule composition and method which is gelatin, BSE, plasticizer and preservative free, which is less sensitive to temperature, humidity and climate changes during manufacture and storage while remaining dimensionally and microbially stable.