Abstract: Repression of CD36 vasculature in stromal tissues surrounding a pre-cancerous lesion provides is indicative of increased risk of subsequent progression to invasive cancer. Methods of assessing progression risk by measuring the abundance of CD36 vasculature in stromal tissues surrounding a precancerous lesion are provided, useful for various cancer types, including for assessing the risk of DCIS progression to breast cancer. Immunohistochemical analysis methods and diagnostic thresholds are provided, as well as associated methods of treatment and diagnostic kits.

Abstract: Embodiments are provided for characterizing a biological sample. In some embodiments, one can estimate the risk that a subject with ductal carcinoma in situ will have a subsequent DCIS event and/or invasive cancers.

Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.

Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.

Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.

Abstract: The present invention provides a radiation device that includes a device for retaining therein the body part in a uniform position. In addition, at least two reference materials that have attenuation characteristics are used and retained in the retaining device. The reference materials are being positioned for the comparative determination during a simultaneous irradiation of the body part and the reference materials. The attenuation characteristics of the reference materials are selected in correspondence to the attenuation characteristics of the body materials in the body part. A radiation device for simultaneously irradiating the body part and the reference materials is used to create attenuated beams. A detector is used to detect the attenuated beams as attenuated values. A calculating device is included for calculating the proportion of the body materials that define a particular body part of interest based on the attenuated values of the materials and the body part.