Patents by Inventor Karlheinz Zick

Karlheinz Zick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASSAY AND METHOD FOR DETERMINING CDC ELICITING ANTIBODIES
    Publication number: 20180017572
    Abstract: Herein is reported a method for determining complement dependent cytotoxicity of a composition comprising i) a first binding site that specifically binds to a first epitope on a first antigen, which is conjugated to a first Fc-region polypeptide of human origin, and ii) a second binding site that specifically binds to a second epitope on a second antigen, which is conjugated to a second Fc-region polypeptide of human origin, wherein the method comprises the steps of incubating a cell expressing the first antigen and the second antigen with the composition; adding rabbit complement to the mixture; and determining cell lysis and thereby determining complement dependent cytotoxicity of the composition.
    Type: Application
    Filed: June 16, 2017
    Publication date: January 18, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Sonja Offner, Karlheinz Zick