Patents by Inventor Karlien Kristal BOON-CEELEN

Karlien Kristal BOON-CEELEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prosthetic valve and method of making a prosthetic valve
    Patent number: 11376123
    Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet attached to a supporting element, which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: July 5, 2022
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paul Frederik Gründeman, Jolanda Kluin, Karlien Kristal Boon-Ceelen, Thomas König
  • PROSTHETIC VALVE AND METHOD OF MAKING A PROSTHETIC VALVE
    Publication number: 20200107928
    Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet attached to a supporting element, which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets.
    Type: Application
    Filed: December 3, 2019
    Publication date: April 9, 2020
    Inventors: Paul Frederik GRÜNDEMAN, Jolanda KLUIN, Karlien Kristal BOON-CEELEN, Thomas KÖNIG
  • Prosthetic valve and method of making a prosthetic valve
    Patent number: 10524902
    Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet (3) attached to a supporting element (2), which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface (700) to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets. The invention also relates to a leaflet assembly for use in a prosthetic valve, and to methods of making the prosthetic valve, including making the leaflet assembly.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: January 7, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Paul Frederik Gründeman, Jolanda Kluin, Karlien Kristal Boon-Ceelen, Thomas König
  • PROSTHETIC VALVE AND METHOD OF MAKING A PROSTHETIC VALVE
    Publication number: 20180193137
    Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet (3) attached to a supporting element (2), which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface (700) to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets. The invention also relates to a leaflet assembly for use in a prosthetic valve, and to methods of making the prosthetic valve, including making the leaflet assembly.
    Type: Application
    Filed: December 28, 2017
    Publication date: July 12, 2018
    Inventors: Paul Frederik GRÜNDEMAN, Jolanda KLUIN, Karlien Kristal BOON-CEELEN, Thomas KÖNIG