Patents by Inventor Karol K. Mikula

Karol K. Mikula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Eugenol enhancement of transdermal drug delivery
    Patent number: 4888362
    Abstract: Disclosed herein are compositions and methods for enhancing the transdermal delivery of physiologically active agents across mammalian skin or membranes and which comprise a percutaneous transfer enhancing amount of eugenol and a drug.
    Type: Grant
    Filed: January 16, 1987
    Date of Patent: December 19, 1989
    Assignee: American Home Products Corp.
    Inventors: Thomas W. Leonard, Karol K. Mikula, Marcia S. Schlesinger
  • Carvone enhancement of transdermal drug delivery
    Patent number: 4888360
    Abstract: Disclosed herein are compositions and methods for enhancing the transdermal delivery of physiologically active agents across mammalian skin or membranes and which comprise a percutaneous transfer enhancing amount of 1-carvone and a drug.
    Type: Grant
    Filed: January 16, 1987
    Date of Patent: December 19, 1989
    Assignee: American Home Products Corporation
    Inventors: Thomas W. Leonard, Karol K. Mikula, Marcia S. Schlesinger
  • Transdermal drug delivery system
    Patent number: 4820525
    Abstract: The invention provides a transdermal/transmucosal pharmaceutical delivery system having an improved drug reservoir comprising a thin layer of foamed material made from high molecular weight polyethylene, the foamed material having a void volume of at lesat 20% per unit of surface area and a narrow pore size variation per unit of surface area.
    Type: Grant
    Filed: September 17, 1987
    Date of Patent: April 11, 1989
    Assignee: American Home Products Corporation (Del.)
    Inventors: Thomas W. Leonard, Robin P. Enever, Karol K. Mikula
  • Insulin administration using methyl and propyl paraben
    Patent number: 4789660
    Abstract: A therapeutic composition for trans-mucosal administration in the treatment of diabetes including insulin, as an adjuvant a water-soluble fusidic acid salt and as a co-adjuvant methylparaben and/or propylparaben.
    Type: Grant
    Filed: September 10, 1987
    Date of Patent: December 6, 1988
    Assignee: American Home Products Corporation
    Inventors: Robin P. Enever, Thomas W. Leonard, Karol K. Mikula