Abstract: A method and associated optimization system make simple and fast determination of possibilities to optimize a number of medical facility resources comprising machine and personnel components regarding their efficiency. Here, a simulation model is provided numerically representing facility components, within which simulation model a number of component-specific distinguishing parameters are associated with each component and that moreover comprises a number of superordinate distinguishing parameters. An initialization parameter set is created via association of an initial value with each distinguishing parameter. An objective function of the distinguishing parameters is determined and at least one distinguishing parameter selected from the superordinate distinguishing parameters is defined as variable. The/every variable distinguishing parameter is varied according to a predetermined optimization algorithm with regard to a mathematical optimization of an objective function.